Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE21PLI)

DME Name	NADPH-dependent nitroreductase (nfrA1) DME Info
Gene Name	nfrA1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

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3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Nitrofurantoin	DM7PQIK	Urinary tract infection	GC08	Approved	[1], [2]
Nitrofurazone	DMSM2KE	Skin burns	ME65.0	Approved	[1], [2]
Riboflavin	DM8YMWE	Acne vulgaris	ED80	Approved	[1]
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Molecule Interaction Atlas

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References

1	Conversion of NfsA, the major Escherichia coli nitroreductase, to a flavin reductase with an activity similar to that of Frp, a flavin reductase in Vibrio harveyi, by a single amino acid substitution. J Bacteriol. 1998 Jan;180(2):422-5.
2	Bacillus subtilis isolated from the human gastrointestinal tract. Res Microbiol. 2009 Mar;160(2):134-43.