Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE95LJC)

DME Name	Thimet oligopeptidase (THOP1) DME Info
UniProt ID	THOP1_HUMAN
Gene Name	THOP1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Gonadorelin	DMAQ469	Hypothalamic hypogonadism	5A61.2	Approved	[1]
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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Bradykinin	DM4R6UV	N. A.	N. A.	Phase 1	[2]
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Molecule Interaction Atlas

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References

1	Sleep deprivation changes thimet oligopeptidase (THOP1) expression and activity in rat brain. Heliyon. 2019 Nov 26;5(11):e02896.
2	Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE). Epilepsia. 2014 May;55(5):754-62.