Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEX2KIA)

DME Name	Steroid 17-alpha-monooxygenase (CYP17A1) DME Info
Gene Name	CYP17A1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aminophenazone	DMY2AH1	N. A.	N. A.	Phase 4	[1]
Dihydrotestosterone	DM3S8XC	Prostate hyperplasia	GA90	Phase 4	[2]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dexniguldipine	DMLZIT2	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 2	[3]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS	DM1G4S9	Discovery agent	N.A.	Investigative	[4]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Contribution of human hepatic cytochrome P450s and steroidogenic CYP17 to the N-demethylation of aminopyrine. Xenobiotica. 1999 Feb;29(2):187-93.
2	Identifying susceptibility genes for prostate cancer--a family-based association study of polymorphisms in CYP17, CYP19, CYP11A1, and LH-beta. Cancer Epidemiol Biomarkers Prev. 2005 Aug;14(8):2035-9.
3	In vitro metabolism of dexamethasone (DEX) in human liver and kidney: the involvement of CYP3A4 and CYP17 (17,20 LYASE) and molecular modelling studies. Biochem Pharmacol. 1997 Sep 1;54(5):605-11.
4	Transcriptional complexes at the CYP17 CRS. Endocr Res. 2002 Nov;28(4):551-8.