Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT4LXBC)

• DTT Name: Hedgehog signaling pathway (HS pathway) DTT Info
• Gene Name: HS pathway

Molecule-Related Drug & Molecule List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Itraconazole	DMCR1MV	Aspergillosis	1F20	Approved	[1]
PF-04449913	DMSB068	Chronic myelomonocytic leukaemia	2A40	Approved	[2]

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ENV-101	DMFOI3T	Idiopathic pulmonary fibrosis	CB03.4	Phase 2	[3]
Patidegib	DM2NJYC	Basal cell carcinoma	2C32	Phase 2	[4]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
• [3] Development of taladegib as a sonic hedgehog signaling pathway inhibitor. Arch Pharm Res. 2017 Dec;40(12):1390-1393.
• [4] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)