Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT7KNZQ)

• DTT Name: Thymidine kinase 2 (Mt-TK2) DTT Info
• Gene Name: dnk

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MT-1621	DMUNBMA	Thymidine kinase 2 deficiency	5C55.1	Phase 3	[1]

3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine	DMU3VWA	Discovery agent	N.A.	Investigative	[2]
1-[5-(triphenylmethoxy)pentyl]thymine	DMFHBJM	Discovery agent	N.A.	Investigative	[2]
1-[6-(triphenylmethoxy)hexyl]thymine	DM5NVHO	Discovery agent	N.A.	Investigative	[2]

References

• [1] Clinical pipeline report, company report or official report of Modis Therapeutics.
• [2] N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors. J Med Chem. 2006 Dec 28;49(26):7766-73.