Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT96HUR)

DTT Name	Cell surface A33 antigen (GPA33) DTT Info
Gene Name	GPA33

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
KRN-330	DMA5B1S	Colorectal cancer	2B91.Z	Phase 1/2	[1]
MGD007	DMAHWLR	Colorectal cancer	2B91.Z	Phase 1/2	[2]
HuA33	DMB3LQU	Colorectal cancer	2B91.Z	Phase 1	[3]
Radiolabelled-huA33	DMIEJ0W	Colorectal cancer	2B91.Z	Phase 1	[3]
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Molecule Interaction Atlas

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References

1	Phase 1/2 study of KRN330, a fully human anti-A33 monoclonal antibody, plus irinotecan as second-line treatment for patients with metastatic colorectal cancer. Invest New Drugs. 2014 Aug;32(4):682-90.
2	Bispecific antibodies rise again. Nat Rev Drug Discov. 2014 Nov;13(11):799-801.
3	(124)I-huA33 antibody PET of colorectal cancer. J Nucl Med. 2011 Aug;52(8):1173-80.