Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTB9CIL)

• DTT Name: Prokineticin receptor-1 (PROKR1) DTT Info
• Gene Name: PROKR1

Molecule-Related Drug & Molecule List

4 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9475795, 19	DMGPDEF	N. A.	N. A.	Patented	[1]
US9475795, 80	DM0ZDL3	N. A.	N. A.	Patented	[1]
US9475795, 89	DMR6ODL	N. A.	N. A.	Patented	[1]
ZINC19658740	DMLZDAK	N. A.	N. A.	Patented	[2]

3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
IS1	DMNF70P	Discovery agent	N.A.	Investigative	[3]
IS20	DMQ5GA9	Discovery agent	N.A.	Investigative	[3]
triazine compound PC10	DMCLA2D	Discovery agent	N.A.	Investigative	[4]

References

• [1] Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases. US9475795.
• [2] Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases. US10167273.
• [3] Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1. PLoS One. 2015 Apr 1;10(4):e0121027.
• [4] Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain. J Nucl Med. 2011 Apr;52(4):600-7.