Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTBW580)

DTT Name	TAX transcriptionally-activated glycoprotein 1 (OX40) DTT Info
UniProt ID	TNFL4_HUMAN
Gene Name	TNFSF4

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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5 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AMG 386	DMQJXL4	Breast cancer	2C60-2C65	Phase 3	[1]
RG7888	DM2SWI8	Solid tumour/cancer	2A00-2F9Z	Phase 2	[2]
MEDI6383	DM1YSMD	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
mRNA-2416	DMFTAWU	Lymphoma	2A80-2A86	Phase 1	[4]
mRNA-2752	DMUKBI2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[5]
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Molecule Interaction Atlas

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References

1	Clinical targeting of the TNF and TNFR superfamilies.Nat Rev Drug Discov.2013 Feb;12(2):147-68.
2	Anti-tumor efficacy and biomarker evaluation of agonistic anti-OX40 antibodies in preclinical models. J Immunother Cancer. 2014; 2(Suppl 3): P105.
3	J Clin Oncol 33, 2015 (suppl; abstr 3056).
4	Clinical pipeline report, company report or official report of Moderna Therapeutics.
5	Clinical pipeline report, company report or official report of Moderna Therapeutics.