Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTFOUV4)

DTT Name	BCL-2 messenger RNA (BCL2 mRNA) DTT Info
Gene Name	BCL2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PNT-2258	DMUVON0	Diffuse large B-cell lymphoma	2A81	Phase 2	[1]
Beclanorsen	DMXVRI0	leukaemia	2A60-2B33	Phase 1/2	[2]
BP1002	DMI826O	Haematopoietic/lymphoid cancer	2B33.5	Phase 1	[3]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BP-100-1.02	DMGEYFB	Lymphoma	2A80-2A86	Investigative	[4]
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Molecule Interaction Atlas

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References

1	Clinical pipeline report, company report or official report of ProNAi.
2	Combination of novel imidazopyridazine mps-1 kinase inhibitors and bcl-2 family protein inhibitors. ACS Med Chem Lett. 2014 Jul 30;6(1):7-8.
3	Clinical pipeline report, company report or official report of Bio-Path Holdings.
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2844).