Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTI1PRE)

• DTT Name: G-protein coupled receptor GPCR33 (GPRC6A) DTT Info
• UniProt ID: GPC6A_HUMAN
• Gene Name: GPRC6A

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-citrulline	DMT4K0Z	Acute lung injury	NB32.3	Phase 3	[1]

4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
calindol	DMY9P6E	Discovery agent	N.A.	Investigative	[2]
L-lysine	DMOD5CK	Discovery agent	N.A.	Investigative	[1]
L-Ornithine	DMHKGCM	Discovery agent	N.A.	Investigative	[1]
L-Serine	DM6WPIS	Discovery agent	N.A.	Investigative	[1]

References

• [1] Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids. Mol Pharmacol. 2005 Mar;67(3):589-97.
• [2] Molecular determinants of non-competitive antagonist binding to the mouse GPRC6A receptor. Cell Calcium. 2009 Nov-Dec;46(5-6):323-32.