Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTI84H7)

• DTT Name: Cytochrome P450 1B1 (CYP1B1) DTT Info
• Gene Name: CYP1B1

Molecule-Related Drug & Molecule List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PINOCEMBRIN	DM96VWD	N. A.	N. A.	Phase 2	[1]
NARINGENIN	DMHAZLM	N. A.	N. A.	Phase 1	[1]

18 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-[2-(3,5-Dimethoxy-phenyl)-vinyl]-thiophene	DMX1TIU	Discovery agent	N.A.	Investigative	[2]
3-[2-(3,5-Dimethoxy-phenyl)-vinyl]-furan	DMXE1LC	Discovery agent	N.A.	Investigative	[2]
4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-pyridine	DM4ENGI	Discovery agent	N.A.	Investigative	[2]
ACACETIN	DMQOB0X	Discovery agent	N.A.	Investigative	[1]
APIGENIN	DMI3491	Discovery agent	N.A.	Investigative	[1]
Chrysin	DM7V2LG	Discovery agent	N.A.	Investigative	[1]
CHRYSOERIOL	DM96ECL	Discovery agent	N.A.	Investigative	[1]
DIOSMETIN	DM4KXIM	Discovery agent	N.A.	Investigative	[1]
ERIODICTYOL	DMD3BEQ	Discovery agent	N.A.	Investigative	[1]
Galangin	DM5TQ2O	Discovery agent	N.A.	Investigative	[1]
HOMOERIODICTYOL	DM1SDN8	Discovery agent	N.A.	Investigative	[1]
ISORHAMNETIN	DMQ4Z6E	Discovery agent	N.A.	Investigative	[1]
ISOSAKUTANETIN	DMJS7MV	Discovery agent	N.A.	Investigative	[1]
KAEMPFERIDE	DMUWA2G	Discovery agent	N.A.	Investigative	[1]
KAEMPFEROL	DMHEMUB	Discovery agent	N.A.	Investigative	[1]
N-(2,4-Dimethoxy-phenyl)-3,5-dimethoxy-benzamide	DME0YBF	Discovery agent	N.A.	Investigative	[2]
TAMARIXETIN	DM0EP51	Discovery agent	N.A.	Investigative	[1]
TRISMETHOXYRESVERATROL	DM6USPC	Discovery agent	N.A.	Investigative	[2]

References

• [1] Selective inhibition of methoxyflavonoids on human CYP1B1 activity. Bioorg Med Chem. 2010 Sep 1;18(17):6310-5.
• [2] Design, synthesis, and discovery of novel trans-stilbene analogues as potent and selective human cytochrome P450 1B1 inhibitors. J Med Chem. 2002 Jan 3;45(1):160-4.