Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTJDUNO)

• DTT Name: T-cell surface antigen CD2 (CD2) DTT Info
• Gene Name: CD2

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Siplizumab	DM75RFJ	Lymphoma	2A80-2A86	Phase 2	[1]

6 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alpha-D-Mannose	DMF5DLW	Discovery agent	N.A.	Investigative	[2]
Cyclo(1,10)EIYDPGDDIK	DMFUG05	Discovery agent	N.A.	Investigative	[3]
Cyclo(1,10)H-EIYDPGDDIK-OH	DM5CBQ9	Discovery agent	N.A.	Investigative	[3]
Cyclo(1,11)H-ESIYDPGDDIK-OH	DM4A1TF	Discovery agent	N.A.	Investigative	[3]
Cyclo(1,12)PenIYDTKGKNVLC-OH	DMVDS8B	Discovery agent	N.A.	Investigative	[4]
Pen(Acm)AQFRKEKETFC(Acm)-OH	DM81AWU	Discovery agent	N.A.	Investigative	[4]

References

• [1] Emerging drugs for moderate-to-severe psoriasis. Expert Opin Emerg Drugs. 2005 Feb;10(1):35-52.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [3] Design of beta-hairpin peptides for modulation of cell adhesion by beta-turn constraint. J Med Chem. 2009 Feb 12;52(3):726-36.
• [4] Structure-activity studies of peptides from the "hot-spot" region of human CD2 protein: development of peptides for immunomodulation. J Med Chem. 2005 Oct 6;48(20):6236-49.