Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTLOHU4)

DTT Name	Mycobacterium Decaprenylphosphoryl-beta-D-ribose oxidase (McyB dprE1) DTT Info
Gene Name	McyB dprE1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BTZ-043	DMVXBSW	Tuberculosis	1B10-1B14	Phase 2	[1]
TBA-7371	DMZTOJ6	Tuberculosis	1B10-1B14	Phase 2	[2]
OPC-167832	DMZB6LO	Tuberculosis	1B10-1B14	Phase 1/2	[3]
Macozinone	DM0HKU7	Mycobacterium infection	1B10-1B21	Phase 1	[4]
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Molecule Interaction Atlas

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References

1	Clinical pipeline report, company report or official report of TB
2	Clinical pipeline report, company report or official report of TB Alliance.
3	OPC-167832, a Novel Carbostyril Derivative with Potent Antituberculosis Activity as a DprE1 Inhibitor. Antimicrob Agents Chemother. 2020 May 21;64(6):e02020-19.
4	Spirocyclic and Bicyclic 8-Nitrobenzothiazinones for Tuberculosis with Improved Physicochemical and Pharmacokinetic Properties. ACS Med Chem Lett. 2019 Feb 23;10(3):348-351.