Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTM42UJ)

• DTT Name: Hepatitis B virus Capsid protein (HBV C) DTT Info
• Gene Name: HBV C

Molecule-Related Drug & Molecule List

8 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABI-H0731	DMX1KDM	Hepatitis B	1E51	Phase 2	[1]
ABI-H2158	DM6X70G	Hepatitis B	1E51	Phase 2	[2]
JNJ-56136379	DM9RW6H	Hepatitis B	1E51	Phase 2	[3]
A204	DMF1LYP	Hepatitis B virus infection	1E51.0	Phase 1	[4]
ABI-H3733	DM4TN6W	Hepatitis B	1E51	Phase 1	[2]
EDP-514	DM8KRA3	Chronic HBV infection	1E51.0Z	Phase 1	[5]
RG7907	DMKVIS5	Hepatitis B	1E51	Phase 1	[6]
ZM-H1505R	DMX6AJ8	Hepatitis B	1E51	Phase 1	[7]

References

• [1] Safety, pharmacokinetics, and antiviral effects of ABI-H0731, a hepatitis B virus core inhibitor: a randomised, placebo-controlled phase 1 trial. Lancet Gastroenterol Hepatol. 2020 Feb;5(2):152-166.
• [2] Clinical pipeline report, company report or official report of Assembly Biosciences.
• [3] JNJ-56136379, an HBV Capsid Assembly Modulator, Is Well-Tolerated and Has Antiviral Activity in a Phase 1 Study of Patients With Chronic Infection. Gastroenterology. 2020 Aug;159(2):521-533.e9.
• [4] Clinical pipeline report, company report or official report of Klus Pharma
• [5] Clinical pipeline report, company report or official report of Enanta Pharmaceuticals.
• [6] Clinical pipeline report, company report or official report of Roche.
• [7] Clinical pipeline report, company report or official report of Shanghai Zhimeng Biopharma.