Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTQY2EJ)

• DTT Name: TERT messenger RNA (TERT mRNA) DTT Info
• Gene Name: TERT

Molecule-Related Drug & Molecule List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[1]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[1]

52 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1,3-bis(3,4-dihydroxyphenyl)prop-2-en-1-one	DMELSV1	Discovery agent	N.A.	Investigative	[2]
2,3-Dimethylnaphtho[2,3-f]quinoxaline-7,12-dione	DMKV9EZ	Discovery agent	N.A.	Investigative	[3]
2,7-Bis(3-chloropropionamido)anthraquinone	DMT9JHV	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(4-chlorobutyramido)anthraquinone	DM8VWQ2	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(acetamido)anthraquinone	DM2EPM4	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(benzoamido)anthraquinone	DMEQC4X	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(butyramido)anthraquinone	DM9S8LY	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(chloroacetamido)anthraquinone	DM4MYAR	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(cyclohexanecarbonamido)anthraquinone	DMTPZ8D	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(cyclopentanecarbonamido)anthraquinone	DMP3EZ8	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(cyclopropanecarbonamido)anthraquinone	DMY3V2B	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(phenylacetamido)anthraquinone	DMEVIBT	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(phenylpropionamido)anthraquinone	DMDKXEY	Discovery agent	N.A.	Investigative	[4]
2,7-Bis(propionamido)anthraquinone	DM2D1EJ	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(butylamino)acetamido]anthraquinone	DM3GTV0	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(diethylamino)acetamido]anthraquinone	DMKDSGE	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(dimethylamino)acetamido]anthraquinone	DMNW5PL	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(ethylamino)acetamido]anthraquinone	DMZ7EAC	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(isobutylamino)acetamido]anthraquinone	DMM4T1Q	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(isopropylamino)acetamido]anthraquinone	DMRQGWX	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(piperazino)acetamido]anthraquinone	DMPE8GX	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(piperidino)acetamido]anthraquinone	DMITF0P	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(propylamino)acetamido]anthraquinone	DMH89TO	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[2-(pyrrolidino)acetamido]anthraquinone	DMHVKIJ	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[3-(butylamino)propionamido]anthraquinone	DM4V63W	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[3-(ethylamino)propionamido]anthraquinone	DMC537F	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[3-(piperazino)propionamido]anthraquinone	DMOZEKQ	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[3-(piperidino)propionamido]anthraquinone	DMET693	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[3-(propylamino)propionamido]anthraquinone	DM6I90F	Discovery agent	N.A.	Investigative	[4]
2,7-Bis[3-(pyrrolidino)propionamido]anthraquinone	DMD6ZV5	Discovery agent	N.A.	Investigative	[4]
2,7-diaminoanthraquinone	DME0TZU	Discovery agent	N.A.	Investigative	[4]
2,7-Dinitroantraquinone	DMN56VM	Discovery agent	N.A.	Investigative	[4]
2-Butyl-1(3)H-anthra[1,2-d]imidazole-6,11-dione	DMY7RM8	Discovery agent	N.A.	Investigative	[3]
2-Heptyl-1(3)H-anthra[1,2-d]imidazole-6,11-dione	DMX45WE	Discovery agent	N.A.	Investigative	[3]
2-Methyl-1(3)H-anthrasimidazole-6,11-dione	DMKTQB2	Discovery agent	N.A.	Investigative	[3]
7,8,3',4'-tetrahydroxyflavone	DMOBEL9	Discovery agent	N.A.	Investigative	[2]
AURASPERONE A	DMDKH8N	Discovery agent	N.A.	Investigative	[5]
Cantide + Cisplatin	DM9IG2P	Tumour	2A00-2F9Z	Investigative	[1]
HOE-33258	DMKOMP2	Discovery agent	N.A.	Investigative	[6]
LIVIDOMYCIN A	DM6J1BY	Discovery agent	N.A.	Investigative	[6]
NSC-745794	DM1ETX5	Discovery agent	N.A.	Investigative	[3]
NSC-745795	DMI2GFM	Discovery agent	N.A.	Investigative	[3]
NSC-745796	DM8JMBI	Discovery agent	N.A.	Investigative	[3]
NSC-745797	DM9YAPX	Discovery agent	N.A.	Investigative	[3]
NSC-745798	DMSPQYV	Discovery agent	N.A.	Investigative	[3]
NSC-745799	DML6OMH	Discovery agent	N.A.	Investigative	[3]
NSC-745883	DMVA6R0	Discovery agent	N.A.	Investigative	[3]
NSC-745884	DM8W0J3	Discovery agent	N.A.	Investigative	[3]
NSC-745885	DMZQ803	Discovery agent	N.A.	Investigative	[3]
NSC-745886	DMHBYN5	Discovery agent	N.A.	Investigative	[3]
NSC-745887	DMG9BWY	Discovery agent	N.A.	Investigative	[3]
NSC-745888	DMWHYND	Discovery agent	N.A.	Investigative	[3]

References

• [1] Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.
• [2] Catecholic flavonoids acting as telomerase inhibitors. J Med Chem. 2004 Dec 16;47(26):6466-75.
• [3] Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28.
• [4] Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86.
• [5] New dimeric naphthopyrones from Aspergillus niger. J Nat Prod. 2003 Jan;66(1):136-9.
• [6] Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3467-71.