Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTU5A6Q)

• DTT Name: Adenine nucleotide translocator 1 (SLC25A4) DTT Info
• Gene Name: SLC25A4

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[1]

4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
bongkrek acid	DMWALXQ	Discovery agent	N.A.	Investigative	[2]
Carboxyatractyloside	DMEORTQ	Discovery agent	N.A.	Investigative	[3]
Cardiolipin	DMCSMX4	Discovery agent	N.A.	Investigative	[4]
Di-Stearoyl-3-Sn-Phosphatidylcholine	DM0GQJ2	Discovery agent	N.A.	Investigative	[3]

References

• [1] Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite. Mol Pharmacol. 2002 May;61(5):1255-62.
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1062).
• [3] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [4] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.