General Information of DTT (ID: TTWNL74)

DTT Name V-set and immunoglobulin domain-containing protein 9 (TIGIT) DTT Info
Gene Name TIGIT

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
8 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
AB154 DMUES7Y Non-small-cell lung cancer 2C25 Phase 3 [1]
Ociperlimab DMEDSVJ Non-small-cell lung cancer 2C25.Y Phase 3 [2]
GSK4428859 DMIOIU8 Aggressive cancer 2A00-2F9Z Phase 2 [3]
Rilvegostomig DMDWCM2 Non-small-cell lung cancer 2C25 Phase 1/2 [4]
ASP8374 DMA71OL Solid tumour/cancer 2A00-2F9Z Phase 1 [5]
COM902 DMR6T8L Solid tumour/cancer 2A00-2F9Z Phase 1 [6]
M6223 DM6J085 Solid tumour/cancer 2A00-2F9Z Phase 1 [7]
SEA-TGT DM7GUH3 Solid tumour/cancer 2A00-2F9Z Phase 1 [8]
------------------------------------------------------------------------------------
⏷ Show the Full List of 8 Clinical Trial Drug(s)
Molecule Interaction Atlas

References

1 Clinical pipeline report, company report or official report of Arcus Biosciences.
2 Clinical pipeline report, company report or official report of BeiGene.
3 Clinical pipeline report, company report or official report of GlaxoSmithKline
4 ClinicalTrials.gov (NCT04995523) Phase I/II, Open-label, Dose Escalation and Dose Expansion Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC. U.S.National Institutes of Health.
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6 COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade. Cancer Immunol Immunother. 2021 Apr 26.
7 ClinicalTrials.gov (NCT04457778) First in Human Study of M6223. U.S. National Institutes of Health.
8 Clinical pipeline report, company report or official report of Seagen.