General Information of DTT (ID: TTYRO4F)

DTT Name Sclerostin (SOST) DTT Info
Gene Name SOST

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
1 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Romosozumab DMFJZN0 Postmenopausal osteoporosis FB83.11 Approved [1]
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4 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
UX143 DM89NIB Osteogenesis imperfecta LD24.K0 Phase 3 [2]
BPS-804 DMDYZRS Metabolic bone disease FB8Y Phase 2 [3]
LY2541546 DMTVU2Q Osteoporosis FB83.0 Phase 2 [4]
AMG 167 DMUETI2 Osteoporosis FB83.0 Phase 1 [5]
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Molecule Interaction Atlas

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
2 Clinical pipeline report, company report or official report of Ultragenyx Pharmaceutical
3 WO patent application no. 2010,1001,79, Self-forming gel system for sustained drug delivery.
4 Rat-specific decreases in platelet count caused by a humanized monoclonal antibody against sclerostin. Toxicol Sci. 2012 Feb;125(2):586-94.
5 Osteoporosis - a current view of pharmacological prevention and treatment. Drug Des Devel Ther. 2013; 7: 435-448.