Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZFDBT)

DTT Name	Follicle-stimulating hormone receptor (FSHR) DTT Info
UniProt ID	FSHR_HUMAN
Gene Name	FSHR

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Approved Drug(s)

Download the Complete Related Drug List

3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Follitropin beta	DM2JTS5	Female infertility	GA31.Z	Approved	[1]
Menotropins	DM4CF18	Female infertility	GA31.Z	Approved	[2]
Urofollitropin	DMG9HIA	Female infertility	GA31.Z	Approved	[3]
------------------------------------------------------------------------------------

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Suramin	DMTOUY9	African trypanosomiasis	1F51	Phase 1	[4], [5]
------------------------------------------------------------------------------------

4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
FSHR NAM	DMPRMOD	Contraception	QA21	Investigative	[6]
Long-acting FSH conjugate	DMD32IN	Female infertility	GA31.Z	Investigative	[6]
PRX-111	DMSPH30	Female infertility	GA31.Z	Investigative	[7]
Recombinant follicle stimulating hormone	DMNHOI3	Female infertility	GA31.Z	Investigative	[6]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Follitropin-alpha (Gonal-F) versus follitropin-beta (Puregon) in controlled ovarian hyperstimulation for in vitro fertilization: is there any diffe... Fertil Steril. 2009 Apr;91(4 Suppl):1522-5.
2	The role of gonadotropins in ovulation induction. Am J Obstet Gynecol. 1995 Feb;172(2 Pt 2):759-65.
3	Follicle-stimulating hormone in clinical practice: an update. Treat Endocrinol. 2004;3(3):161-71.
4	Suramin: clinical uses and structure-activity relationships. Mini Rev Med Chem. 2008 Nov;8(13):1384-94.
5	Follicle stimulating hormone receptor (FSHR) antagonist and epithelial ovarian cancer (EOC). J Exp Ther Oncol. 2007;6(3):201-4.
6	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 253).
7	A naturally occurring basically charged human follicle-stimulating hormone (FSH) variant inhibits FSH-induced androgen aromatization and tissue-type plasminogen activator enzyme activity in vitro. Neuroendocrinology. 1998 Mar;67(3):153-63.