Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZVSJ2)

• DTT Name: Sarcoplasmic/endoplasmic reticulum calcium ATPase (ATP2A) DTT Info
• Gene Name: ATP2A

Molecule-Related Drug & Molecule List

7 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Artemisinin	DMOY7W3	Malaria	1F40-1F45	Approved	[1]
Artemisinin SP	DMFETDK	Malaria	1F40-1F45	Approved	[1]
Artesunate	DMR27C8	Infection of P. falciparum	1F40	Approved	[1]
Dihydroartemisinin	DMBXVMZ	Malaria	1F40-1F45	Approved	[1]
OZ277	DM1YB0R	Malaria	1F40-1F45	Approved	[1]
Piperaquine	DMT70RC	Malaria	1F40-1F45	Approved	[1]
Pyronaridine	DMUWAM2	Malaria	1F40-1F45	Approved	[1]

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Vanadate	DMQL0KF	Psoriatic arthritis	FA21	Phase 3	[2]

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
THAPSIGARGIN	DMDMQIE	N. A.	N. A.	Preclinical	[3]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cyclopiazonic acid	DMPJ08G	Discovery agent	N.A.	Investigative	[2]

References

• [1] The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs. Curr Med Chem. 2008;15(2):161-71.
• [2] Expression and functional characterization of a Plasmodium falciparum Ca2+-ATPase (PfATP4) belonging to a subclass unique to apicomplexan organisms. J Biol Chem. 2001 Apr 6;276(14):10782-7.
• [3] Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase. Bioorg Med Chem. 2010 Aug 1;18(15):5634-46.