Details of Disease

Disease Name

Cervicitis

cervicitis (disease); cervicitis

Definition

An acute or chronic inflammatory process that affects the cervix. Causes include sexually transmitted diseases and bacterial infections. Clinical manifestations include abnormal vaginal bleeding and vaginal discharge.

Disease Hierarchy

DIS1HG31: Cervix disorder

DIS4KMW5: Cervicitis

Disease Identifiers

MONDO ID

MONDO_0002345

MESH ID

D002575

UMLS CUI

C0007860

MedGen ID

3338

HPO ID

HP:0030160

SNOMED CT ID

37610005

General Information of Disease (ID: DIS4KMW5)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Cefixime	DMY60I8	Approved	Small molecular drug	[1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 3 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
AMHR2	TTZDCPK	Strong	Altered Expression	[2]
MAP3K3	TTJZNIG	Strong	Altered Expression	[3]
PDXP	TT9UYG4	Strong	Genetic Variation	[4]
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This Disease Is Related to 3 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
AQP8	OT99JKME	Strong	Altered Expression	[5]
HIPK1	OTSEA8RS	Strong	Altered Expression	[6]
SAV1	OTSAEV92	Strong	Biomarker	[7]
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References

1	Cefixime FDA Label
2	Expression of AMHR2 and C-KIT in cervical lesions in Uyghur Women of Xinjiang, China.Medicine (Baltimore). 2018 Jun;97(22):e10793. doi: 10.1097/MD.0000000000010793.
3	MEKK3 and survivin expression in cervical cancer: association with clinicopathological factors and prognosis.Asian Pac J Cancer Prev. 2014;15(13):5271-6. doi: 10.7314/apjcp.2014.15.13.5271.
4	Correlation between cervical carcinogenesis and tobacco use by sexual partners.Hell J Nucl Med. 2019 Sep-Dec;22 Suppl 2:184-190.
5	Significance and expression of aquaporin 1, 3, 8 in cervical carcinoma in Xinjiang Uygur women of China.Asian Pac J Cancer Prev. 2012;13(5):1971-5. doi: 10.7314/apjcp.2012.13.5.1971.
6	Sipi soup inhibits cancerassociated fibroblast activation and the inflammatory process by downregulating long noncoding RNA HIPK1AS.Mol Med Rep. 2018 Aug;18(2):1361-1368. doi: 10.3892/mmr.2018.9144. Epub 2018 Jun 6.
7	Detection of torque teno midi virus/small anellovirus (TTMDV/SAV) in chronic cervicitis and cervical tumors in Isfahan, Iran.Arch Virol. 2012 Feb;157(2):291-5. doi: 10.1007/s00705-011-1169-7. Epub 2011 Nov 16.