Details of Disease | DrugMAP

General Information of Disease (ID: DIS6U70H)

Disease Name	Obsolete acrodysostosis with multiple hormone resistance
Disease Hierarchy	DIS01GPL: Grass pollen hypersensitivity DIS6U70H: Obsolete acrodysostosis with multiple hormone resistance

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
PDE4D	TTSKMI8	Supportive	Autosomal dominant	[1]
PRKAR1A	TTNAHEX	Definitive	Autosomal dominant	[2]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
PDE4D	OT1RWFV0	Supportive	Autosomal dominant	[1]
PRKAR1A	OT589JA2	Definitive	Autosomal dominant	[2]
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References

1	Exome sequencing identifies PDE4D mutations as another cause of acrodysostosis. Am J Hum Genet. 2012 Apr 6;90(4):740-5. doi: 10.1016/j.ajhg.2012.03.003. Epub 2012 Mar 29.
2	Recurrent PRKAR1A mutation in acrodysostosis with hormone resistance. N Engl J Med. 2011 Jun 9;364(23):2218-26. doi: 10.1056/NEJMoa1012717.