Details of Disease

General Information of Disease (ID: DISAZL0D)

Disease Name Congenital syphilis
Synonyms mother-to-child transmission of syphilis; congenital syphilis; MTCT of syphilis
Definition
A life-threatening bacterial infection of the newborn caused by Treponema pallidum. It is transmitted to the infant from a mother with syphilis through the placenta during pregnancy. Signs and symptoms include irritability, fever, failure to thrive, saddle nose, cutaneous rash, and pneumonia.
Disease Hierarchy
DIS2D2DJ: Infectious embryofetopathy
DISJ73BS: Syphilis
DISAZL0D: Congenital syphilis
Disease Identifiers
MONDO ID
MONDO_0005714
MESH ID
D013590
UMLS CUI
C0039131
MedGen ID
52622
Orphanet ID
499009
SNOMED CT ID
35742006

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Benzylpenicillin DMS9503 Phase 3 Small molecular drug [1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 Congenital syphilis in a preterm newborn with gastrointestinal disorders and postnatal growth restriction. Ital J Pediatr. 2022 Dec 29;48(1):205.