Details of Disease

General Information of Disease (ID: DISD8N1U)

Disease Name	Deep vein thrombosis
Synonyms	intravenous leiomyomatosis
Disease Class	BD71: Deep vein thrombosis
Definition	A rare benign neoplasm characterized by the presence of smooth muscle cells growing within veins.
Disease Hierarchy	DISNOOME: Leiomyomatosis DISD8N1U: Deep vein thrombosis
ICD Code	ICD-11 ICD-11: BD71 Expand ICD-11 'BD71 Expand ICD-9 437.6,453,453.40,671.5,671.9
Disease Identifiers	MONDO ID MONDO_0003614 UMLS CUI C0346200 MedGen ID 83417 SNOMED CT ID 1157175007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 9 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Ardeparin	DMYRX8B	Approved	Small molecular drug	[1]
Certoparin sodium	DMUR94J	Approved	NA	[2]
Dermatan sulfate	DM69HTC	Approved	Small molecular drug	[2]
Desirudin	DMF81MQ	Approved	Small molecular drug	[3]
Fibrinogen	DMYGOFV	Approved	NA	[4]
Fondaparinux sodium	DMWS3FH	Approved	Small molecular drug	[5]
Heparin Sodium	DM9KHZL	Approved	NA	[6]
Rivaroxaban	DMQMBZ1	Approved	Small molecular drug	[7]
Warfarin	DMJYCVW	Approved	Small molecular drug	[8]
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⏷ Show the Full List of 9 Drug(s)

This Disease is Treated as An Indication in 1 Drugs in Phase 2 Trial

Drug Name	Drug ID	Highest Status	Drug Type	REF
Heparin	DM4ZP3W	Phase 2/3 Trial	Small molecular drug	[9]
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This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
CY-1748	DM0X147	Terminated	NA	[10]
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This Disease is Treated as An Indication in 3 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
BLX-155	DMLC4PE	Investigative	NA	[11]
Glysopep	DMWV5MO	Investigative	NA	[11]
TT-105	DM3BYQM	Investigative	NA	[11]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Pharmacologic profile of certoparin. Expert Opin Investig Drugs. 1999 Mar;8(3):315-27.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6458).
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6749).
5	Fondaparinux sodium FDA Label
6	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4214).
7	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6388).
8	Warfarin FDA Label
9	Heparin FDA Label
10	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005714)
11	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.