Details of Disease | DrugMAP

General Information of Disease (ID: DISIRPQ9)

Disease Name	Familial Alzheimer-like prion disease
Disease Hierarchy	DISD715V: Hereditary neurological disease DISOUMB0: Prion disease DISIRPQ9: Familial Alzheimer-like prion disease
Disease Identifiers	MONDO ID MONDO_0017233 UMLS CUI C4303482 MedGen ID 929151 Orphanet ID 280397 SNOMED CT ID 721219005

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
PRNP	TTY5F9C	Definitive	GermlineCausalMutation	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
PRNP	OTE85L1Q	Supportive	Autosomal dominant	[1]
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References

1	Familial prion disease with Alzheimer disease-like tau pathology and clinical phenotype. Ann Neurol. 2011 Apr;69(4):712-20. doi: 10.1002/ana.22264. Epub 2011 Mar 17.