Details of Disease

General Information of Disease (ID: DISLHH9P)

Disease Name Ovarian dysgenesis 2
Synonyms
ovarian dysgenesis, hypergonadotropic, X-linked; ovarian failure, hypergonadotropic, due to ovarian dysgenesis; premature ovarian failure 4; ODG2; primary ovarian failure caused by mutation in BMP15; BMP15 primary ovarian failure; ovarian dysgenesis type 2; ovarian dysgenesis 2
Definition Any primary ovarian failure in which the cause of the disease is a mutation in the BMP15 gene.
Disease Hierarchy
DISWASB4: Female hypogonadism
DISBB9HA: 46 XX gonadal dysgenesis
DISLHH9P: Ovarian dysgenesis 2
Disease Identifiers
MONDO ID
MONDO_0010349
MESH ID
C564499
UMLS CUI
C1845294
OMIM ID
300510
MedGen ID
336903

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
BMP15 OT2G3YR1 Strong X-linked [1]
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References

1 Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. Mol Endocrinol. 2001 Jun;15(6):854-66. doi: 10.1210/mend.15.6.0662.