Details of Disease

General Information of Disease (ID: DISQUZFO)

Disease Name Anal cancer
Synonyms cancer of the anus; cancer of anus; anal cancer; Ca anus; carcinoma of the anus; carcinoma of anus; anus carcinoma; anal carcinoma
Disease Class 2C00: Anal cancer
Definition A carcinoma that arises from epithelial cells of the anus
Disease Hierarchy
DISW6NMZ: Anus cancer
DISH9F1N: Carcinoma
DIS8FRR7: Rectal carcinoma
DISQUZFO: Anal cancer
ICD Code
ICD-11
ICD-11: 2C00
Expand ICD-11
'2C00
Expand ICD-10
'C21; 'C21.0; 'C21.1; 'C21.2; 'C21.8
Disease Identifiers
MONDO ID
MONDO_0003199
MESH ID
D001005
UMLS CUI
C0279637
MedGen ID
76006

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Axalimogene filolisbac DMAXBCB Phase 3 NA [1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
IFNB1 TT4TZ8J Strong Therapeutic [2]
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This Disease Is Related to 1 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
NDUFS7 DEIW03B Limited Biomarker [3]
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This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
SPRR2A OT62ZU6B Strong Biomarker [4]
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References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Anorectal melanoma: successful treatment by surgical excision and combination chemoimmunotherapy.Hepatogastroenterology. 2002 Nov-Dec;49(48):1545-8.
3 Incidence of first and second primary cancers diagnosed among people with HIV, 1985-2013: a population-based, registry linkage study.Lancet HIV. 2018 Nov;5(11):e647-e655. doi: 10.1016/S2352-3018(18)30179-6. Epub 2018 Sep 21.
4 Expression analysis and mutational screening of the epithelium-specific ets gene-1 (ESE-1) in patients with squamous anal cancer.Int J Oncol. 2000 Aug;17(2):265-70. doi: 10.3892/ijo.17.2.265.