Details of Disease | DrugMAP

General Information of Disease (ID: DISR63SG)

Disease Name	Coumarin resistance
Synonyms	coumarin sensitivity; warfarin resistance; coumarin, poor metabolism of; warfarin sensitivity; coumarin resistance
Disease Hierarchy	DISYKSRF: Genetic disease DISR63SG: Coumarin resistance
Disease Identifiers	MONDO ID MONDO_0007390 MESH ID C563039 UMLS CUI C0750384 OMIM ID 122700 MedGen ID 148193

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
CYP2C9	TTR40YJ	Strong	Biomarker	[1]
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This Disease Is Related to 1 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
CYP2A6	DEJVYAZ	No Known	Unknown	[2]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CYP2A6	OT52TWG3	No Known	Unknown	[2]
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References

1	VKORC1 and CYP2C9 genotypes in Egyptian patients with warfarin resistance.Blood Coagul Fibrinolysis. 2016 Mar;27(2):121-6. doi: 10.1097/MBC.0000000000000168.
2	The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.