Details of Disease | DrugMAP

General Information of Disease (ID: DISRWZEG)

Disease Name	Retinitis
Synonyms	retina inflammation; inflammation of retina
Definition	Inflammation of the retina.
Disease Hierarchy	DISWD40R: Disease DISB4B0F: Retinopathy DISIBJSM: Posterior uveitis DISRWZEG: Retinitis
Disease Identifiers	MONDO ID MONDO_0002708 MESH ID D012173 UMLS CUI C0035333 MedGen ID 19765 HPO ID HP:0032118 SNOMED CT ID 399463004

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 3 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
CRH	TTA7YIZ	Strong	Biomarker	[1]
MIF	TT6804T	Strong	Biomarker	[2]
PRKCG	TTRFOXJ	Strong	Genetic Variation	[3]
------------------------------------------------------------------------------------

This Disease Is Related to 1 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
SLC9A6	DTN0JXW	Strong	Genetic Variation	[4]
------------------------------------------------------------------------------------

This Disease Is Related to 3 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
DPYSL5	OT6F9T6F	Strong	Biomarker	[5]
NDP	OTGDJ4US	Strong	Biomarker	[6]
RLBP1	OTCY4D6B	Strong	Genetic Variation	[7]
------------------------------------------------------------------------------------

References

1	Fas/Fas ligand-associated apoptosis in experimental autoimmune uveoretinitis in rodents: role of proinflammatory corticotropin-releasing hormone.Exp Eye Res. 2001 Jun;72(6):623-9. doi: 10.1006/exer.2001.0992.
2	Inhibition of experimental autoimmune uveoretinitis with anti-macrophage migration inhibitory factor antibodies.Curr Eye Res. 2000 Feb;20(2):109-14.
3	R659S mutation of gammaPKC is susceptible to cell death: implication of this mutation/polymorphism in the pathogenesis of retinitis pigmentosa.Neurochem Int. 2006 Dec;49(7):669-75. doi: 10.1016/j.neuint.2006.05.005. Epub 2006 Jul 7.
4	Novel mutation in SLC9A6 gene in a patient with Christianson syndrome and retinitis pigmentosum.Brain Dev. 2013 Feb;35(2):172-6. doi: 10.1016/j.braindev.2012.03.010. Epub 2012 Apr 26.
5	Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG.Ann Neurol. 2003 Jul;54(1):38-50. doi: 10.1002/ana.10587.
6	Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina.Sci Rep. 2018 Apr 13;8(1):5970. doi: 10.1038/s41598-018-24476-y.
7	Novel mutation in RLBP1 gene in a Japanese patient with retinitis punctata albescens.Am J Ophthalmol. 2005 Jun;139(6):1133-5. doi: 10.1016/j.ajo.2004.12.011.