Details of Disease

General Information of Disease (ID: DISVLUUA)

• Disease Name: Renal transplantation
• Disease Class: NE84: Transplant rejection
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISVLUUA: Renal transplantation
• ICD Code:
  ICD-11: ICD-11: NE84
  ICD-10: ICD-10: D89.8
  ICD-9: ICD-9: 279.5
  Expand ICD-9: 279.5

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Efalizumab	DMCKL5V	Approved	Antibody	[1]

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
QPI-1002	DMDU5Y2	Phase 3	siRNA drug	[2]
Sotrastaurin acetate	DME53YS	Phase 2	Small molecular drug	[3]

This Disease is Treated as An Indication in 2 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
AG490	DM3WKO5	Terminated	Small molecular drug	[4]
PNU156804	DM23ZHN	Terminated	Small molecular drug	[5]

This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
NC1153	DM6XGFE	Investigative	Small molecular drug	[6]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6593).
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [3] Emerging drugs for psoriasis. Expert Opin Emerg Drugs. 2009 Mar;14(1):145-63.
• [4] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5916).
• [5] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008393)
• [6] Immunotherapy for De Novo renal transplantation: what's in the pipeline Drugs. 2006;66(13):1665-84.