Details of Disease

General Information of Disease (ID: DISVXFB7)

Disease Name	Vaginal infection
Synonyms	Vaginal Infection; PV - Vaginal infection; Infective vaginitis; Vaginal infection; vaginal infection
Disease Class	GA02: Vaginitis
Definition	An infectious process affecting the vagina. Symptoms include pain and purulent discharge.
Disease Hierarchy	DISCYOMR: Vaginitis DISEM33Q: Infectious disease DISVXFB7: Vaginal infection
ICD Code	ICD-11 ICD-11: GA02.0 ICD-10 ICD-10: N76.0
Disease Identifiers	MONDO ID MONDO_0023557 UMLS CUI C0404521 MedGen ID 140795 SNOMED CT ID 237091009

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
RGN-259	DMSF10P	Phase 2	NA	[1]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 4 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ELK4	OTVSSEOE	Strong	Biomarker	[2]
LRRCC1	OTVEBJ1V	Strong	Biomarker	[2]
PTPRH	OTDUHQGF	Strong	Biomarker	[2]
SCLT1	OT2ZSSP4	Strong	Biomarker	[2]
------------------------------------------------------------------------------------

References

1	Clinical pipeline report, company report or official report of Regulus Therapeutics.
2	The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium.Infect Immun. 2003 Jun;71(6):3227-34. doi: 10.1128/IAI.71.6.3227-3234.2003.