Details of Disease

General Information of Disease (ID: DISXHT8N)

Disease Name Tertiary syphilis
Synonyms late tertiary syphilis; tertiary syphilis; late syphilis
Definition A stage of syphilis that occurs fifteen to thirty years after the initial infection; it can include gumma formation and cardiovascular or central nervous system involvement (neurosyphilis).
Disease Hierarchy
DISJ73BS: Syphilis
DISXHT8N: Tertiary syphilis
Disease Identifiers
MONDO ID
MONDO_0004497
MESH ID
C536774
UMLS CUI
C0153188
MedGen ID
56297
SNOMED CT ID
72083004

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Benzylpenicillin DMS9503 Phase 3 Small molecular drug [1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
PTER OTBYJHDG Strong Biomarker [2]
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References

1 A rare case of tertiary syphilis spondylodiscitis of the upper cervical spine: Diagnostic and therapeutic complexity, review of literature. Orthop Rev (Pavia). 2020 Jun 25;12(Suppl 1):8675.
2 Incidence and Predictors of Serological Treatment Response in Early and Late Syphilis Among People Living With HIV.Open Forum Infect Dis. 2018 Nov 30;6(1):ofy324. doi: 10.1093/ofid/ofy324. eCollection 2019 Jan.