Details of Disease

General Information of Disease (ID: DISXXS3L)

• Disease Name: Colonic disorder
• Synonyms: disorder of colon; disease or disorder of colon; disease of colon; colon disorder; colon disease or disorder; colon disease
• Definition: Pathological processes in the colon region of the large intestine (intestine, large).
• Disease Hierarchy:
  DISWD40R: Disease
  DISKU8JE: Large intestine disorder
  DISXXS3L: Colonic disorder
• Disease Identifiers:
  MONDO ID: MONDO_0003409
  MESH ID: D003108
  UMLS CUI: C0009373
  MedGen ID: 1049
  SNOMED CT ID: 128524007

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 5 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CRTC3	OTVIGVUW	Strong	Genetic Variation	[1]
KIF3B	OT0HJREB	Strong	Genetic Variation	[1]
NRIP1	OTIZOJQV	Strong	Genetic Variation	[1]
PHGR1	OTY3GTEP	Strong	Altered Expression	[2]
TRAF3IP2	OTLLZERL	Strong	Genetic Variation	[1]

References

• [1] Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway.Inflamm Bowel Dis. 2016 Apr;22(4):862-9. doi: 10.1097/MIB.0000000000000705.
• [2] The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer.Transl Oncol. 2018 Apr;11(2):436-443. doi: 10.1016/j.tranon.2018.01.015. Epub 2018 Feb 21.