DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD)
|
OTOMP6TH
|
PK3CD_HUMAN
|
Decreases Activity
|
[14] |
Poly polymerase 1 (PARP1)
|
OT310QSG
|
PARP1_HUMAN
|
Increases Cleavage
|
[14] |
G1/S-specific cyclin-D1 (CCND1)
|
OT8HPTKJ
|
CCND1_HUMAN
|
Decreases Expression
|
[14] |
Mitogen-activated protein kinase 3 (MAPK3)
|
OTCYKGKO
|
MK03_HUMAN
|
Decreases Phosphorylation
|
[14] |
Mitogen-activated protein kinase 1 (MAPK1)
|
OTH85PI5
|
MK01_HUMAN
|
Decreases Phosphorylation
|
[14] |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB)
|
OTO8JQJA
|
PK3CB_HUMAN
|
Decreases Activity
|
[14] |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PIK3CG)
|
OT3FAU4Y
|
PK3CG_HUMAN
|
Decreases Activity
|
[14] |
Hepatocyte growth factor receptor (MET)
|
OT7K55MU
|
MET_HUMAN
|
Increases Expression
|
[12] |
Receptor tyrosine-protein kinase erbB-3 (ERBB3)
|
OTRSST0A
|
ERBB3_HUMAN
|
Increases Expression
|
[12] |
Tuberin (TSC2)
|
OT47LWI9
|
TSC2_HUMAN
|
Decreases Phosphorylation
|
[15] |
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
|
OT2YYI1A
|
MCL1_HUMAN
|
Decreases Expression
|
[12] |
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)
|
OTHBQVD5
|
4EBP1_HUMAN
|
Decreases Phosphorylation
|
[15] |
Cyclin-G2 (CCNG2)
|
OTII38K2
|
CCNG2_HUMAN
|
Increases Expression
|
[12] |
Atos homolog protein A (ATOSA)
|
OTWFM5G0
|
ATOSA_HUMAN
|
Increases Expression
|
[12] |
Phosphoinositide-3-kinase-interacting protein 1 (PIK3IP1)
|
OTWE5G4T
|
P3IP1_HUMAN
|
Increases Expression
|
[12] |
Serine/threonine-protein kinase STK11 (STK11)
|
OT1YZSP3
|
STK11_HUMAN
|
Increases Response To Substance
|
[12] |
Epidermal growth factor receptor (EGFR)
|
OTAPLO1S
|
EGFR_HUMAN
|
Increases Response To Substance
|
[12] |
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)
|
OTOWDUNT
|
PTEN_HUMAN
|
Increases Response To Substance
|
[12] |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA)
|
OTTOMI8J
|
PK3CA_HUMAN
|
Increases Response To Substance
|
[12] |
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