General Information of Drug Combination (ID: DCIZGA3)

Drug Combination Name
Lapatinib Panobinostat
Indication
Disease Entry Status REF
Breast Cancer Phase 1 [1]
Component Drugs Lapatinib   DM3BH1Y Panobinostat   DM58WKG
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Lapatinib
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Approved [2]
Gastroesophageal junction adenocarcinoma 2B71 Approved [3]
Melanoma 2C30 Approved [3]
Lapatinib Interacts with 3 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Erbb2 tyrosine kinase receptor (HER2) TT6EO5L ERBB2_HUMAN Inhibitor [8]
Epidermal growth factor receptor (EGFR) TTGKNB4 EGFR_HUMAN Inhibitor [8]
Eukaryotic elongation factor 2 kinase (eEF-2K) TT1QFLA EF2K_HUMAN Inhibitor [9]
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Lapatinib Interacts with 2 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [10]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [11]
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Lapatinib Interacts with 4 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [12]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Metabolism [13]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Metabolism [12]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Metabolism [13]
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Lapatinib Interacts with 36 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Decreases Activity [14]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Decreases Activity [15]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Increases Expression [16]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Increases Expression [16]
NAD(P)H dehydrogenase 1 (NQO1) OTZGGIVK NQO1_HUMAN Increases Expression [16]
Nuclear factor erythroid 2-related factor 2 (NFE2L2) OT0HENJ5 NF2L2_HUMAN Increases Activity [16]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [17]
Estrogen receptor (ESR1) OTKLU61J ESR1_HUMAN Decreases Activity [14]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [18]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Expression [19]
DNA topoisomerase 1 (TOP1) OT51O0CF TOP1_HUMAN Decreases Expression [20]
DNA topoisomerase 2-alpha (TOP2A) OT6LPS08 TOP2A_HUMAN Decreases Expression [20]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Expression [20]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Decreases Expression [18]
Phosphatidylcholine translocator ABCB4 (ABCB4) OTE6PY83 MDR3_HUMAN Decreases Activity [21]
Receptor tyrosine-protein kinase erbB-3 (ERBB3) OTRSST0A ERBB3_HUMAN Decreases Activity [22]
Alanine aminotransferase 1 (GPT) OTOXOA0Q ALAT1_HUMAN Increases Secretion [23]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Decreases Expression [14]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Activity [18]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Activity [18]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Decreases Activity [14]
DNA replication licensing factor MCM7 (MCM7) OT6FXC6K MCM7_HUMAN Decreases Expression [18]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Increases Activity [20]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Increases Expression [14]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Increases Activity [20]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Increases Activity [20]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Increases Expression [19]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Decreases Activity [24]
GTPase KRas (KRAS) OT78QCN8 RASK_HUMAN Decreases Response To Substance [25]
HLA class II histocompatibility antigen, DQ alpha 1 chain (HLA-DQA1) OTC6GISG DQA1_HUMAN Increases ADR [26]
Zinc finger protein SNAI1 (SNAI1) OTDPYAMC SNAI1_HUMAN Decreases Response To Substance [27]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Increases Metabolism [20]
Cytochrome P450 3A7 (CYP3A7) OTTCDHHM CP3A7_HUMAN Increases Metabolism [20]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Decreases Response To Substance [27]
Tenascin-X (TNXB) OTVBWAV5 TENX_HUMAN Increases ADR [26]
HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1) OTVVI3UI DQB1_HUMAN Increases ADR [26]
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⏷ Show the Full List of 36 DOT(s)
Indication(s) of Panobinostat
Disease Entry ICD 11 Status REF
Chronic graft versus host disease N.A. Approved [4]
Lung cancer 2C25.0 Approved [4]
Multiple myeloma 2A83 Approved [5]
Non-small-cell lung cancer 2C25.Y Approved [4]
Plasma cell myeloma 2A83.1 Approved [4]
Primary cutaneous T-cell lymphoma N.A. Approved [4]
Type-2 diabetes 5A11 Phase 3 [6]
Primary myelofibrosis 2A20.2 Phase 2 [6]
Panobinostat Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Histone deacetylase 1 (HDAC1) TT6R7JZ HDAC1_HUMAN Inhibitor [31]
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Panobinostat Interacts with 1 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [32]
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Panobinostat Interacts with 1 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [33]
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Panobinostat Interacts with 1019 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [34]
DNA-directed RNA polymerase II subunit RPB1 (POLR2A) OTHJQ1DZ RPB1_HUMAN Decreases Phosphorylation [34]
Diphosphoinositol polyphosphate phosphohydrolase NUDT4B (NUDT4) OTA6ICI2 NUD4B_HUMAN Increases Expression [28]
ADP-ribose glycohydrolase MACROD2 (MACROD2) OTNQCHC6 MACD2_HUMAN Decreases Expression [28]
Transmembrane protein 218 (TMEM218) OTM46L89 TM218_HUMAN Decreases Expression [28]
Cadherin-like and PC-esterase domain-containing protein 1 (CPED1) OTJJPZOZ CPED1_HUMAN Increases Expression [28]
Killer cell lectin-like receptor subfamily G member 2 (KLRG2) OTBLEXSC KLRG2_HUMAN Increases Expression [28]
Protein FAM149A (FAM149A) OTMDM0RI F149A_HUMAN Decreases Expression [28]
Developmental pluripotency-associated 5 protein (DPPA5) OTLZC371 DPPA5_HUMAN Increases Expression [28]
Metalloprotease TIKI2 (TRABD2B) OTI7B18G TIKI2_HUMAN Increases Expression [28]
RNA binding protein fox-1 homolog 3 (RBFOX3) OTL0F3D6 RFOX3_HUMAN Decreases Expression [28]
Coiled-coil domain-containing protein 69 (CCDC69) OT43MI0R CCD69_HUMAN Increases Expression [28]
Ras association domain-containing protein 10 (RASSF10) OTGB7EBG RASFA_HUMAN Decreases Expression [28]
Very-long-chain (HACD1) OTEC7EP7 HACD1_HUMAN Increases Expression [28]
NALCN channel auxiliary factor 1 (NALF1) OT8OMCFD NALF1_HUMAN Decreases Expression [28]
Rab GTPase-activating protein 1-like, isoform 10 (RABGAP1L) OT7QO47I RBG10_HUMAN Increases Expression [28]
Alternative prion protein (PRNP) OTE85L1Q APRIO_HUMAN Increases Expression [28]
Suppressyn (ERVH48-1) OT303JGE SUPYN_HUMAN Increases Expression [28]
PDZ and LIM domain protein 1 (PDLIM1) OT4EGCPG PDLI1_HUMAN Increases Expression [28]
Activator of apoptosis harakiri (HRK) OTR4GWJ0 HRK_HUMAN Increases Expression [28]
Proteinase-activated receptor 3 (F2RL2) OT982ECU PAR3_HUMAN Decreases Expression [28]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) OTQ4W7MT TR11B_HUMAN Increases Expression [28]
Sulfotransferase 1C2 (SULT1C2) OT07MMZS ST1C2_HUMAN Increases Expression [28]
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) OTKOZRZP PLOD2_HUMAN Increases Expression [28]
Beta-1,3-N-acetylglucosaminyltransferase manic fringe (MFNG) OTUX45ZF MFNG_HUMAN Decreases Expression [28]
Podocalyxin (PODXL) OTPNQXF3 PODXL_HUMAN Increases Expression [28]
E3 ubiquitin-protein ligase TRIM38 (TRIM38) OT6SP1M9 TRI38_HUMAN Increases Expression [28]
Nuclear factor 1 B-type (NFIB) OTX94PD0 NFIB_HUMAN Increases Expression [28]
Claudin-4 (CLDN4) OT9C4PZ4 CLD4_HUMAN Increases Expression [28]
Class E basic helix-loop-helix protein 40 (BHLHE40) OTITX14U BHE40_HUMAN Increases Expression [28]
Suppressor of cytokine signaling 2 (SOCS2) OTBPNKJQ SOCS2_HUMAN Increases Expression [28]
Astrotactin-1 (ASTN1) OT23FQIB ASTN1_HUMAN Decreases Expression [28]
Suppressor of cytokine signaling 3 (SOCS3) OTY183WJ SOCS3_HUMAN Decreases Expression [28]
Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1) OTFX1KCG DC1I1_HUMAN Increases Expression [28]
Transmembrane gamma-carboxyglutamic acid protein 1 (PRRG1) OTMH6OWG TMG1_HUMAN Increases Expression [28]
Putative transcription factor Ovo-like 1 (OVOL1) OTFJ62UI OVOL1_HUMAN Increases Expression [28]
Neuropilin-1 (NRP1) OTCGULYV NRP1_HUMAN Increases Expression [28]
Tumor necrosis factor ligand superfamily member 11 (TNFSF11) OTJEPKEQ TNF11_HUMAN Increases Expression [28]
Probable proton-coupled zinc antiporter SLC30A4 (SLC30A4) OTUYJNBS ZNT4_HUMAN Increases Expression [28]
Interferon regulatory factor 6 (IRF6) OTKJ44EV IRF6_HUMAN Increases Expression [28]
Calmegin (CLGN) OTEWVFQV CLGN_HUMAN Decreases Expression [28]
Semaphorin-3E (SEMA3E) OTD4S36H SEM3E_HUMAN Increases Expression [28]
Serine/threonine-protein kinase DCLK1 (DCLK1) OTVSPS98 DCLK1_HUMAN Increases Expression [28]
Angiopoietin-2 (ANGPT2) OTEQK65P ANGP2_HUMAN Increases Expression [28]
Phospholipid scramblase 1 (PLSCR1) OTGY9B5T PLS1_HUMAN Increases Expression [28]
Mitogen-activated protein kinase 13 (MAPK13) OT0W9GE7 MK13_HUMAN Increases Expression [28]
DNA-directed RNA polymerase III subunit RPC7 (POLR3G) OTU3TGQ9 RPC7_HUMAN Increases Expression [28]
Prosaposin receptor GPR37 (GPR37) OTIMDDI3 GPR37_HUMAN Increases Expression [28]
Monocarboxylate transporter 5 (SLC16A4) OT1YXBKC MOT5_HUMAN Increases Expression [28]
TOX high mobility group box family member 3 (TOX3) OTC9NR4W TOX3_HUMAN Decreases Expression [28]
Suppressor of cytokine signaling 1 (SOCS1) OTWA9KFU SOCS1_HUMAN Increases Expression [28]
Regulator of G-protein signaling 5 (RGS5) OTUY0Q2I RGS5_HUMAN Increases Expression [28]
Leucine-rich repeat transmembrane protein FLRT2 (FLRT2) OTGD8TID FLRT2_HUMAN Decreases Expression [28]
Rho GTPase-activating protein 6 (ARHGAP6) OTNVXXFX RHG06_HUMAN Increases Expression [28]
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM12) OTZKOTDB ADA12_HUMAN Decreases Expression [28]
Proline dehydrogenase 1, mitochondrial (PRODH) OT7SQ1C7 PROD_HUMAN Increases Expression [28]
Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1) OTIK337D TGFI1_HUMAN Increases Expression [28]
Phospholipid-transporting ATPase IC (ATP8B1) OTALGS63 AT8B1_HUMAN Increases Expression [28]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Decreases Expression [28]
Carbonic anhydrase 12 (CA12) OT6WNFU8 CAH12_HUMAN Increases Expression [28]
Synaptotagmin-7 (SYT7) OTBWAOWY SYT7_HUMAN Increases Expression [28]
Protein sprouty homolog 1 (SPRY1) OT764FXI SPY1_HUMAN Decreases Expression [28]
Zinc finger protein SNAI2 (SNAI2) OT7Y8EJ2 SNAI2_HUMAN Increases Expression [28]
Synaptogyrin-1 (SYNGR1) OT0MBUK5 SNG1_HUMAN Increases Expression [28]
Protocadherin-7 (PCDH7) OTP091X8 PCDH7_HUMAN Increases Expression [28]
Kallikrein-8 (KLK8) OTGVGHXY KLK8_HUMAN Increases Expression [28]
Phospholipid-transporting ATPase IK (ATP8B3) OTZOGEJO AT8B3_HUMAN Increases Expression [28]
Periplakin (PPL) OTTM4WDO PEPL_HUMAN Increases Expression [28]
Lymphocyte antigen 75 (LY75) OTDHBU0N LY75_HUMAN Increases Expression [28]
BMP/retinoic acid-inducible neural-specific protein 1 (BRINP1) OTEUVSCP BRNP1_HUMAN Increases Expression [28]
Homeobox protein DLX-3 (DLX3) OTARP5SQ DLX3_HUMAN Increases Expression [28]
Plexin-C1 (PLXNC1) OTJ5XKYY PLXC1_HUMAN Decreases Expression [28]
Gremlin-1 (GREM1) OTCK4IGV GREM1_HUMAN Increases Expression [28]
Cyclin-T2 (CCNT2) OTBDRH1J CCNT2_HUMAN Decreases Expression [28]
Histone H2B type 1-K (H2BC12) OTQ8V0KG H2B1K_HUMAN Decreases Expression [28]
Growth arrest-specific protein 7 (GAS7) OT0M5TNY GAS7_HUMAN Increases Expression [28]
Protein diaphanous homolog 2 (DIAPH2) OTBEYFEZ DIAP2_HUMAN Increases Expression [28]
Inward rectifier potassium channel 13 (KCNJ13) OTG1CNND KCJ13_HUMAN Decreases Expression [28]
Plexin-A2 (PLXNA2) OTNNBJMQ PLXA2_HUMAN Increases Expression [28]
Frizzled-7 (FZD7) OTTK3F6E FZD7_HUMAN Increases Expression [28]
Slit homolog 1 protein (SLIT1) OT35RBNT SLIT1_HUMAN Increases Expression [28]
Slit homolog 3 protein (SLIT3) OTU8MKEU SLIT3_HUMAN Increases Expression [28]
Probable phospholipid-transporting ATPase IIA (ATP9A) OT328F1L ATP9A_HUMAN Decreases Expression [28]
Microfibrillar-associated protein 3-like (MFAP3L) OTNMHSAH MFA3L_HUMAN Decreases Expression [28]
Protein cordon-bleu (COBL) OTTB4VFQ COBL_HUMAN Increases Expression [28]
Astrotactin-2 (ASTN2) OTF0W2FJ ASTN2_HUMAN Increases Expression [28]
Calcium-transporting ATPase type 2C member 2 (ATP2C2) OTGIHTYQ AT2C2_HUMAN Increases Expression [28]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B) OTL9I7LO GA45B_HUMAN Increases Expression [28]
Core histone macro-H2A.1 (MACROH2A1) OTV2DQDD H2AY_HUMAN Decreases Expression [28]
Filamin-B (FLNB) OTPCOYL6 FLNB_HUMAN Increases Expression [28]
Large neutral amino acids transporter small subunit 3 (SLC43A1) OTQJQY3S LAT3_HUMAN Increases Expression [28]
Transforming acidic coiled-coil-containing protein 1 (TACC1) OTGX20TE TACC1_HUMAN Increases Expression [28]
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) OTLMT95K NDUB1_HUMAN Decreases Expression [28]
Glypican-4 (GPC4) OTUJ14DW GPC4_HUMAN Decreases Expression [28]
Disabled homolog 1 (DAB1) OTPL9MA3 DAB1_HUMAN Decreases Expression [28]
Src kinase-associated phosphoprotein 2 (SKAP2) OTSF44KP SKAP2_HUMAN Increases Expression [28]
Forkhead box protein H1 (FOXH1) OTEXJ9SL FOXH1_HUMAN Increases Expression [28]
PR domain zinc finger protein 1 (PRDM1) OTQLSVBS PRDM1_HUMAN Increases Expression [28]
Scrapie-responsive protein 1 (SCRG1) OTBE7V0P SCRG1_HUMAN Increases Expression [28]
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) OTB4YBVT S2512_HUMAN Increases Expression [28]
Leukocyte cell-derived chemotaxin 1 (CNMD) OTHND8EL CNMD_HUMAN Increases Expression [28]
Short-chain dehydrogenase/reductase 3 (DHRS3) OTSK1DTP DHRS3_HUMAN Increases Expression [28]
Serine/threonine-protein kinase PAK 3 (PAK3) OT80M3BV PAK3_HUMAN Decreases Expression [28]
Lysozyme-like protein 6 (LYZL6) OT6XS67M LYZL6_HUMAN Increases Expression [28]
Retinal dehydrogenase 2 (ALDH1A2) OTJB560Z AL1A2_HUMAN Decreases Expression [28]
Slit homolog 2 protein (SLIT2) OTLS2RJ4 SLIT2_HUMAN Increases Expression [28]
Nucleolar protein 4 (NOL4) OTWI587R NOL4_HUMAN Decreases Expression [28]
Kelch repeat and BTB domain-containing protein 11 (KBTBD11) OTBOY3WH KBTBB_HUMAN Decreases Expression [28]
Unconventional myosin-Id (MYO1D) OTP2RGPN MYO1D_HUMAN Increases Expression [28]
Protein transport protein Sec24D (SEC24D) OTXR3KC9 SC24D_HUMAN Increases Expression [28]
Neurofascin (NFASC) OTBDUXZT NFASC_HUMAN Decreases Expression [28]
Thymocyte selection-associated high mobility group box protein TOX (TOX) OTE8BL5Z TOX_HUMAN Increases Expression [28]
Glutaminase kidney isoform, mitochondrial (GLS) OTGOZG2M GLSK_HUMAN Increases Expression [28]
Rho-related BTB domain-containing protein 3 (RHOBTB3) OT1BFKPH RHBT3_HUMAN Increases Expression [28]
Serine protease 23 (PRSS23) OT6DQAM1 PRS23_HUMAN Decreases Expression [28]
Peripheral-type benzodiazepine receptor-associated protein 1 (TSPOAP1) OTAM8SGF RIMB1_HUMAN Decreases Expression [28]
Chondroitin sulfate proteoglycan 5 (CSPG5) OTXFEBWR CSPG5_HUMAN Decreases Expression [28]
Protocadherin-8 (PCDH8) OTDDOQM2 PCDH8_HUMAN Increases Expression [28]
Histone acetyltransferase KAT7 (KAT7) OTUN98IC KAT7_HUMAN Decreases Expression [28]
Ly6/PLAUR domain-containing protein 3 (LYPD3) OTLR2PYX LYPD3_HUMAN Increases Expression [28]
Homeobox protein SIX3 (SIX3) OTP5E3VU SIX3_HUMAN Decreases Expression [28]
Neuroendocrine secretory protein 55 (GNAS) OTMH8BKJ GNAS3_HUMAN Increases Expression [28]
Claudin-7 (CLDN7) OTNE0XHQ CLD7_HUMAN Increases Expression [28]
Homeobox protein SIX6 (SIX6) OTD1RD9D SIX6_HUMAN Decreases Expression [28]
Protein phosphatase 1 regulatory subunit 3D (PPP1R3D) OTZNC7R2 PPR3D_HUMAN Increases Expression [28]
C-X-C motif chemokine 14 (CXCL14) OTM189TA CXL14_HUMAN Increases Expression [28]
Fibroblast growth factor 19 (FGF19) OT2DVJWY FGF19_HUMAN Increases Expression [28]
Heat shock 70 kDa protein 4L (HSPA4L) OT181WZB HS74L_HUMAN Increases Expression [28]
TBC1 domain family member 8 (TBC1D8) OT2011SS TBCD8_HUMAN Decreases Expression [28]
BAG family molecular chaperone regulator 2 (BAG2) OTI6LD27 BAG2_HUMAN Increases Expression [28]
Claudin-1 (CLDN1) OT27KV99 CLD1_HUMAN Increases Expression [28]
Histone-lysine N-methyltransferase NSD2 (NSD2) OTQ6SW4R NSD2_HUMAN Decreases Expression [28]
Purine nucleoside phosphorylase (PNP) OTO5NIJ2 PNPH_HUMAN Increases Expression [28]
Urokinase-type plasminogen activator (PLAU) OTX0QGKK UROK_HUMAN Increases Expression [28]
Tissue-type plasminogen activator (PLAT) OTQPDNAB TPA_HUMAN Increases Expression [28]
Adenosine deaminase (ADA) OTOX2872 ADA_HUMAN Decreases Expression [28]
Argininosuccinate synthase (ASS1) OT4ZMG0Q ASSY_HUMAN Increases Expression [28]
Serine protease inhibitor Kazal-type 1 (SPINK1) OTSUVAL2 ISK1_HUMAN Increases Expression [28]
Pro-epidermal growth factor (EGF) OTANRJ0L EGF_HUMAN Decreases Expression [28]
Proenkephalin-B (PDYN) OTEJ6430 PDYN_HUMAN Increases Expression [28]
Calcitonin (CALCA) OTZ11LHB CALC_HUMAN Increases Expression [28]
Pro-neuropeptide Y (NPY) OT4ICV3P NPY_HUMAN Increases Expression [28]
Insulin-like growth factor II (IGF2) OTJ4O6MW IGF2_HUMAN Increases Expression [28]
Alpha-1-acid glycoprotein 1 (ORM1) OTZKSBRE A1AG1_HUMAN Decreases Expression [28]
Annexin A1 (ANXA1) OT5OFDJC ANXA1_HUMAN Increases Expression [28]
Platelet-derived growth factor subunit A (PDGFA) OTCMZ0W8 PDGFA_HUMAN Increases Expression [28]
Ornithine aminotransferase, mitochondrial (OAT) OTEKO8CT OAT_HUMAN Increases Expression [28]
N-myc proto-oncogene protein (MYCN) OTWD33K1 MYCN_HUMAN Increases Expression [28]
HLA class II histocompatibility antigen gamma chain (CD74) OTO16X4Q HG2A_HUMAN Increases Expression [28]
Protein S100-B (S100B) OTHHDS33 S100B_HUMAN Increases Expression [28]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Increases Expression [28]
Glycophorin-C (GYPC) OTOEDR7O GLPC_HUMAN Increases Expression [28]
Endothelin-1 (EDN1) OTZCACEG EDN1_HUMAN Increases Expression [28]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Increases Expression [28]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Increases Expression [28]
Fatty acid-binding protein, heart (FABP3) OT562DA1 FABPH_HUMAN Increases Expression [28]
Transcription factor AP-2-alpha (TFAP2A) OTMYT3NK AP2A_HUMAN Increases Expression [28]
Protein kinase C beta type (PRKCB) OTYQ0656 KPCB_HUMAN Increases Expression [28]
Keratin, type I cytoskeletal 18 (KRT18) OTVLQFIP K1C18_HUMAN Increases Expression [28]
Keratin, type II cytoskeletal 8 (KRT8) OTTM4X11 K2C8_HUMAN Increases Expression [28]
Beta-crystallin A3 (CRYBA1) OT8617WJ CRBA1_HUMAN Decreases Expression [28]
Collagen alpha-2(V) chain (COL5A2) OT5VOSQE CO5A2_HUMAN Increases Expression [28]
Protein S100-A6 (S100A6) OTHHPZQ8 S10A6_HUMAN Increases Expression [28]
Neurofilament light polypeptide (NEFL) OTQESJV4 NFL_HUMAN Increases Expression [28]
Neurofilament medium polypeptide (NEFM) OT8VCBNF NFM_HUMAN Increases Expression [28]
Annexin A2 (ANXA2) OTFNS0CC ANXA2_HUMAN Increases Expression [28]
Tyrosine-protein kinase Lyn (LYN) OTP686K2 LYN_HUMAN Increases Expression [28]
Collagen alpha-2(I) chain (COL1A2) OTY7G382 CO1A2_HUMAN Increases Expression [28]
Tumor necrosis factor receptor superfamily member 16 (NGFR) OTPKSM49 TNR16_HUMAN Increases Expression [28]
Complement decay-accelerating factor (CD55) OTZ3HWTO DAF_HUMAN Increases Expression [28]
Asparagine synthetase (ASNS) OT8R922G ASNS_HUMAN Increases Expression [28]
Retinol-binding protein 1 (RBP1) OTRP1MFC RET1_HUMAN Increases Expression [28]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Increases Expression [28]
Tumor-associated calcium signal transducer 2 (TACSTD2) OTLSZR00 TACD2_HUMAN Increases Expression [28]
Protein FAM200B (FAM200B) OTQMCR8C F200B_HUMAN Decreases Expression [28]
Apelin receptor early endogenous ligand (APELA) OTYY0P69 ELA_HUMAN Increases Expression [28]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Expression [28]
Osteopontin (SPP1) OTJGC23Y OSTP_HUMAN Increases Expression [28]
COUP transcription factor 1 (NR2F1) OTGWZWYL COT1_HUMAN Increases Expression [28]
Chromogranin-A (CHGA) OTXYX5JH CMGA_HUMAN Increases Expression [28]
Tissue factor pathway inhibitor (TFPI) OTA0FX16 TFPI1_HUMAN Increases Expression [28]
Mast/stem cell growth factor receptor Kit (KIT) OTHUY3VZ KIT_HUMAN Increases Expression [28]
Retinoic acid receptor beta (RARB) OT367U3E RARB_HUMAN Increases Expression [28]
Thyroid hormone receptor beta (THRB) OTBBIRHZ THB_HUMAN Increases Expression [28]
Clusterin (CLU) OTQGG0JM CLUS_HUMAN Increases Expression [28]
Hyaluronan and proteoglycan link protein 1 (HAPLN1) OTXWR9TJ HPLN1_HUMAN Increases Expression [28]
Microtubule-associated protein 2 (MAP2) OT6UYT3X MTAP2_HUMAN Increases Expression [28]
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) OT2HZK5M GTR3_HUMAN Increases Expression [28]
Serine/threonine-protein kinase pim-1 (PIM1) OTWEKXTU PIM1_HUMAN Increases Expression [28]
Collagen alpha-1(VI) chain (COL6A1) OTYKSCOB CO6A1_HUMAN Increases Expression [28]
Collagen alpha-3(VI) chain (COL6A3) OTAS6R6I CO6A3_HUMAN Increases Expression [28]
Annexin A3 (ANXA3) OTDD8OI7 ANXA3_HUMAN Increases Expression [28]
Bone morphogenetic protein 2 (BMP2) OT23T37S BMP2_HUMAN Increases Expression [28]
Bone morphogenetic protein 4 (BMP4) OTPZMDFH BMP4_HUMAN Increases Expression [28]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Increases Expression [28]
Interferon-induced transmembrane protein 1 (IFITM1) OTECO1G8 IFM1_HUMAN Increases Expression [28]
Gamma-interferon-inducible lysosomal thiol reductase (IFI30) OT9DERT1 GILT_HUMAN Increases Expression [28]
Protein Cripto (CRIPTO) OT46DZXJ TDGF1_HUMAN Increases Expression [28]
Lysosome-associated membrane glycoprotein 2 (LAMP2) OTLUGEJC LAMP2_HUMAN Increases Expression [28]
Phospholipase A2, membrane associated (PLA2G2A) OT1NY7BF PA2GA_HUMAN Increases Expression [28]
Pyruvate kinase PKM (PKM) OTLHHMC2 KPYM_HUMAN Increases Expression [28]
Protein C-ets-1 (ETS1) OT4LVGDN ETS1_HUMAN Increases Expression [28]
Ras-related C3 botulinum toxin substrate 2 (RAC2) OTAOHFNH RAC2_HUMAN Increases Expression [28]
Prostatic acid phosphatase (ACP3) OTSIM0YG PPAP_HUMAN Increases Expression [28]
Ezrin (EZR) OTHBPF1Z EZRI_HUMAN Increases Expression [28]
NAD(P)H dehydrogenase 1 (NQO1) OTZGGIVK NQO1_HUMAN Increases Expression [28]
CD44 antigen (CD44) OT9TTJ41 CD44_HUMAN Increases Expression [28]
Ribosyldihydronicotinamide dehydrogenase (NQO2) OTGDAJRZ NQO2_HUMAN Increases Expression [28]
Platelet-derived growth factor receptor alpha (PDGFRA) OTDJXUCN PGFRA_HUMAN Increases Expression [28]
Solute carrier family 25 member 16 (SLC25A16) OTTTUL91 GDC_HUMAN Increases Expression [28]
Epithelial cell adhesion molecule (EPCAM) OTHBZK5X EPCAM_HUMAN Increases Expression [28]
Carboxypeptidase E (CPE) OTXNTV79 CBPE_HUMAN Increases Expression [28]
Protein kinase C alpha type (PRKCA) OT5UWNRD KPCA_HUMAN Increases Expression [28]
Atrial natriuretic peptide receptor 3 (NPR3) OT6MQP3A ANPRC_HUMAN Increases Expression [28]
cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) OTAKDCMR KAPCA_HUMAN Increases Expression [28]
CCAAT/enhancer-binding protein beta (CEBPB) OTM9MQIA CEBPB_HUMAN Increases Expression [28]
Neuromodulin (GAP43) OT2OTGGV NEUM_HUMAN Increases Expression [28]
Galectin-3 (LGALS3) OTYQT0ZI LEG3_HUMAN Increases Expression [28]
Insulin-like growth factor-binding protein 3 (IGFBP3) OTIX63TX IBP3_HUMAN Decreases Expression [28]
Vascular endothelial growth factor receptor 1 (FLT1) OTT0OGYS VGFR1_HUMAN Increases Expression [28]
Bone morphogenetic protein 7 (BMP7) OTYATP2K BMP7_HUMAN Increases Expression [28]
Integrin beta-5 (ITGB5) OT21MF51 ITB5_HUMAN Decreases Expression [28]
Pituitary adenylate cyclase-activating polypeptide (ADCYAP1) OT0LQH93 PACA_HUMAN Increases Expression [28]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Increases Expression [28]
Cadherin-2 (CDH2) OTH0Y56P CADH2_HUMAN Decreases Expression [28]
Hexokinase-1 (HK1) OTMPHE8O HXK1_HUMAN Increases Expression [28]
Alpha-1-acid glycoprotein 2 (ORM2) OTRJGZP8 A1AG2_HUMAN Decreases Expression [28]
Complement receptor type 2 (CR2) OT90NDLY CR2_HUMAN Increases Expression [28]
Serine protease inhibitor Kazal-type 2 (SPINK2) OTSFBT0G ISK2_HUMAN Increases Expression [28]
POU domain, class 3, transcription factor 3 (POU3F3) OT6BBXPD PO3F3_HUMAN Increases Expression [28]
Muscarinic acetylcholine receptor M3 (CHRM3) OTKSD095 ACM3_HUMAN Increases Expression [28]
Protachykinin-1 (TAC1) OTM842YW TKN1_HUMAN Increases Expression [28]
Serine/threonine-protein kinase MAK (MAK) OTEU2G41 MAK_HUMAN Decreases Expression [28]
Ephrin-A1 (EFNA1) OTU2NUA2 EFNA1_HUMAN Increases Expression [28]
Neurofibromin (NF1) OTC29NHH NF1_HUMAN Decreases Expression [28]
Kit ligand (KITLG) OTB9AVQ4 SCF_HUMAN Increases Expression [28]
Diamine acetyltransferase 1 (SAT1) OT52AU22 SAT1_HUMAN Increases Expression [28]
Receptor tyrosine-protein kinase erbB-3 (ERBB3) OTRSST0A ERBB3_HUMAN Increases Expression [28]
CD9 antigen (CD9) OT2184XU CD9_HUMAN Increases Expression [28]
Bone morphogenetic protein 5 (BMP5) OTC0Y6E0 BMP5_HUMAN Increases Expression [28]
Alpha-(1,3)-fucosyltransferase 4 (FUT4) OTIBXRTL FUT4_HUMAN Increases Expression [28]
Cadherin-3 (CDH3) OTKNLQU7 CADH3_HUMAN Increases Expression [28]
Fibroblast growth factor receptor 3 (FGFR3) OTSAXDIL FGFR3_HUMAN Increases Expression [28]
Calretinin (CALB2) OTSNMCG9 CALB2_HUMAN Increases Expression [28]
Carbonic anhydrase 4 (CA4) OT3K93LZ CAH4_HUMAN Decreases Expression [28]
Prostaglandin G/H synthase 1 (PTGS1) OTHCRLEC PGH1_HUMAN Decreases Expression [28]
Peptidyl-prolyl cis-trans isomerase B (PPIB) OTLPH6KN PPIB_HUMAN Increases Expression [28]
Colorectal mutant cancer protein (MCC) OTQVI1EM CRCM_HUMAN Increases Expression [28]
Paired box protein Pax-7 (PAX7) OTDMQRPO PAX7_HUMAN Increases Expression [28]
Paired box protein Pax-3 (PAX3) OTN5PJZV PAX3_HUMAN Increases Expression [28]
Endothelial transcription factor GATA-2 (GATA2) OTBP2QQ2 GATA2_HUMAN Increases Expression [28]
Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) OTGP7D5Y GATA3_HUMAN Increases Expression [28]
Laminin subunit alpha-2 (LAMA2) OTFROQWE LAMA2_HUMAN Increases Expression [28]
COUP transcription factor 2 (NR2F2) OTJFS67N COT2_HUMAN Decreases Expression [28]
Endothelin receptor type B (EDNRB) OTLLZV3P EDNRB_HUMAN Increases Expression [28]
Protein kinase C eta type (PRKCH) OTC498N5 KPCL_HUMAN Increases Expression [28]
Signal transducer CD24 (CD24) OT7CODJ4 CD24_HUMAN Increases Expression [28]
Endothelin-1 receptor (EDNRA) OTK9T5O3 EDNRA_HUMAN Increases Expression [28]
Atypical chemokine receptor 3 (ACKR3) OTA6GA4F ACKR3_HUMAN Increases Expression [28]
Myelin protein P0 (MPZ) OTAR2YXH MYP0_HUMAN Increases Expression [28]
Rhombotin-2 (LMO2) OTCC370G RBTN2_HUMAN Decreases Expression [28]
Neuropeptide Y receptor type 1 (NPY1R) OT5DA9DY NPY1R_HUMAN Decreases Expression [28]
Collagen alpha-3(V) chain (COL5A3) OTCGC4DM CO5A3_HUMAN Increases Expression [28]
Paired box protein Pax-6 (PAX6) OTOC9876 PAX6_HUMAN Decreases Expression [28]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Increases Expression [28]
Threonine--tRNA ligase 1, cytoplasmic (TARS1) OT0PWST5 SYTC_HUMAN Increases Expression [28]
Serum paraoxonase/arylesterase 1 (PON1) OTD0Z2XO PON1_HUMAN Decreases Expression [28]
Homeobox protein MSX-1 (MSX1) OT5U41ZP MSX1_HUMAN Increases Expression [28]
Gamma-aminobutyric acid receptor subunit beta-3 (GABRB3) OT80C3D4 GBRB3_HUMAN Increases Expression [28]
Ephrin type-A receptor 3 (EPHA3) OTZJF3ML EPHA3_HUMAN Increases Expression [28]
Ephrin type-B receptor 2 (EPHB2) OT8VZ6C5 EPHB2_HUMAN Decreases Expression [28]
Cellular retinoic acid-binding protein 2 (CRABP2) OTY01V9G RABP2_HUMAN Increases Expression [28]
GTP cyclohydrolase 1 feedback regulatory protein (GCHFR) OTEOT8GI GFRP_HUMAN Increases Expression [28]
Translocator protein (TSPO) OTSU7ESK TSPO_HUMAN Increases Expression [28]
CAMPATH-1 antigen (CD52) OT02LDQN CD52_HUMAN Increases Expression [28]
Fibroblast growth factor 9 (FGF9) OT2SKDGM FGF9_HUMAN Decreases Expression [28]
Syndecan-4 (SDC4) OTKUVUGZ SDC4_HUMAN Increases Expression [28]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Increases Expression [28]
Protein S100-A11 (S100A11) OTI57KDN S10AB_HUMAN Increases Expression [28]
Neural cell adhesion molecule L1 (L1CAM) OTNWAQ4Y L1CAM_HUMAN Increases Expression [28]
Gastrin/cholecystokinin type B receptor (CCKBR) OTQSNXOI GASR_HUMAN Decreases Expression [28]
ETS-related transcription factor Elf-1 (ELF1) OTV5LKIA ELF1_HUMAN Increases Expression [28]
Intercellular adhesion molecule 3 (ICAM3) OTTZ5A5D ICAM3_HUMAN Increases Expression [28]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1) OTB06ESI ACSL1_HUMAN Increases Expression [28]
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (MAN1A1) OT6LIGJP MA1A1_HUMAN Increases Expression [28]
Carbonic anhydrase-related protein (CA8) OT9Y8GA8 CAH8_HUMAN Increases Expression [28]
Prostaglandin E2 receptor EP4 subtype (PTGER4) OT2GBV06 PE2R4_HUMAN Increases Expression [28]
Thrombospondin-2 (THBS2) OTXET551 TSP2_HUMAN Increases Expression [28]
Homeobox protein MSX-2 (MSX2) OT1WDKE1 MSX2_HUMAN Increases Expression [28]
Fibrillin-1 (FBN1) OTYCJT63 FBN1_HUMAN Decreases Expression [28]
Transcription factor SOX-11 (SOX11) OT4LG7LA SOX11_HUMAN Decreases Expression [28]
Phosphoglucomutase-1 (PGM1) OT3VM4JX PGM1_HUMAN Increases Expression [28]
Pigment epithelium-derived factor (SERPINF1) OTWZH98J PEDF_HUMAN Decreases Expression [28]
Amiloride-sensitive sodium channel subunit alpha (SCNN1A) OTE2KVZV SCNNA_HUMAN Increases Expression [28]
Transgelin-2 (TAGLN2) OTUXZGDQ TAGL2_HUMAN Increases Expression [28]
Kappa-type opioid receptor (OPRK1) OTXCZF4L OPRK_HUMAN Decreases Expression [28]
Transcription factor SOX-3 (SOX3) OT1CRCOB SOX3_HUMAN Decreases Expression [28]
Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1) OTNBHULA PACR_HUMAN Increases Expression [28]
ETS domain-containing protein Elk-3 (ELK3) OTBM9BHT ELK3_HUMAN Increases Expression [28]
Signal transducer and activator of transcription 6 (STAT6) OTCKMP49 STAT6_HUMAN Increases Expression [28]
Glutamate receptor 3 (GRIA3) OT34CNBR GRIA3_HUMAN Decreases Expression [28]
Leukemia inhibitory factor receptor (LIFR) OT36W9O5 LIFR_HUMAN Increases Expression [28]
C-X-C motif chemokine 5 (CXCL5) OTZOUPCA CXCL5_HUMAN Increases Expression [28]
Excitatory amino acid transporter 1 (SLC1A3) OTILR60R EAA1_HUMAN Increases Expression [28]
Netrin receptor DCC (DCC) OT2C1SHW DCC_HUMAN Increases Expression [28]
Tyrosine-protein kinase SYK (SYK) OTQID87L KSYK_HUMAN Increases Expression [28]
Lysophosphatidic acid receptor 6 (LPAR6) OT4BY3W4 LPAR6_HUMAN Increases Expression [28]
Transcription factor GATA-4 (GATA4) OTQHWAZG GATA4_HUMAN Decreases Expression [28]
Peptidyl-prolyl cis-trans isomerase C (PPIC) OTY5Q42N PPIC_HUMAN Increases Expression [28]
Radiation-inducible immediate-early gene IEX-1 (IER3) OTZJI5FZ IEX1_HUMAN Increases Expression [28]
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) OTZRWTGA IQGA1_HUMAN Increases Expression [28]
Cytosolic phospholipase A2 (PLA2G4A) OTE70SOT PA24A_HUMAN Increases Expression [28]
Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2) OTAOZIGX GBRB2_HUMAN Increases Expression [28]
Retinaldehyde dehydrogenase 3 (ALDH1A3) OT1C9NKQ AL1A3_HUMAN Increases Expression [28]
DNA-binding protein inhibitor ID-4 (ID4) OTPMJ39I ID4_HUMAN Increases Expression [28]
Sodium- and chloride-dependent creatine transporter 1 (SLC6A8) OT88C8JA SC6A8_HUMAN Decreases Expression [28]
Stromal cell-derived factor 1 (CXCL12) OT2QX5LL SDF1_HUMAN Increases Expression [28]
Tissue factor pathway inhibitor 2 (TFPI2) OTZCRWOR TFPI2_HUMAN Increases Expression [28]
Transcription factor SOX-2 (SOX2) OTFAWCAU SOX2_HUMAN Decreases Expression [28]
Transcription factor SOX-9 (SOX9) OTVDJFGN SOX9_HUMAN Increases Expression [28]
Potassium voltage-gated channel subfamily C member 1 (KCNC1) OTW9WF1J KCNC1_HUMAN Decreases Expression [28]
Nuclear receptor-interacting protein 1 (NRIP1) OTIZOJQV NRIP1_HUMAN Increases Expression [28]
Neuropeptide Y receptor type 2 (NPY2R) OTEWQJ6B NPY2R_HUMAN Decreases Expression [28]
Protein ERGIC-53 (LMAN1) OTYHKDEO LMAN1_HUMAN Decreases Expression [28]
Beta-arrestin-1 (ARRB1) OT2NJS37 ARRB1_HUMAN Increases Expression [28]
CCAAT/enhancer-binding protein delta (CEBPD) OTNBIPMY CEBPD_HUMAN Increases Expression [28]
Selenoprotein P (SELENOP) OT02B8IR SEPP1_HUMAN Increases Expression [28]
Histamine N-methyltransferase (HNMT) OT9F303M HNMT_HUMAN Increases Expression [28]
Isocitrate dehydrogenase subunit alpha, mitochondrial (IDH3A) OT5QQB5L IDH3A_HUMAN Increases Expression [28]
Motor neuron and pancreas homeobox protein 1 (MNX1) OTXP9FH1 MNX1_HUMAN Increases Expression [28]
Homeobox protein MOX-1 (MEOX1) OTJEMT2D MEOX1_HUMAN Increases Expression [28]
Sulfotransferase 1A2 (SULT1A2) OT7EJ6LQ ST1A2_HUMAN Increases Expression [28]
Matrix metalloproteinase-14 (MMP14) OT9C197Z MMP14_HUMAN Increases Expression [28]
Protoporphyrinogen oxidase (PPOX) OT75GZ3K PPOX_HUMAN Decreases Expression [28]
Serpin B9 (SERPINB9) OTJ811IF SPB9_HUMAN Increases Expression [28]
LIM/homeobox protein Lhx2 (LHX2) OTK61NP8 LHX2_HUMAN Decreases Expression [28]
ETS translocation variant 1 (ETV1) OT6PMJIK ETV1_HUMAN Decreases Expression [28]
Amiloride-sensitive sodium channel subunit gamma (SCNN1G) OTSJYQVQ SCNNG_HUMAN Increases Expression [28]
Probable global transcription activator SNF2L2 (SMARCA2) OTSGJ8SV SMCA2_HUMAN Increases Expression [28]
Glypican-3 (GPC3) OTWS8WSW GPC3_HUMAN Decreases Expression [28]
Ephrin-A5 (EFNA5) OTOH4DRR EFNA5_HUMAN Decreases Expression [28]
Stanniocalcin-1 (STC1) OTGVVXYF STC1_HUMAN Increases Expression [28]
Homeobox protein GBX-2 (GBX2) OTW0ZI4D GBX2_HUMAN Increases Expression [28]
Beta-crystallin A4 (CRYBA4) OTQJ5XGE CRBA4_HUMAN Decreases Expression [28]
Integrin alpha-8 (ITGA8) OTBH8WFD ITA8_HUMAN Increases Expression [28]
Mitogen-activated protein kinase 10 (MAPK10) OTC46VX1 MK10_HUMAN Decreases Expression [28]
Calcipressin-1 (RCAN1) OT1MVXC7 RCAN1_HUMAN Increases Expression [28]
Monocarboxylate transporter 1 (SLC16A1) OTW1UTZ7 MOT1_HUMAN Increases Expression [28]
Voltage-dependent calcium channel subunit alpha-2/delta-1 (CACNA2D1) OT5YLZIH CA2D1_HUMAN Increases Expression [28]
Ephrin type-A receptor 4 (EPHA4) OT3AMK0C EPHA4_HUMAN Decreases Expression [28]
Paired mesoderm homeobox protein 1 (PRRX1) OTTZK5G8 PRRX1_HUMAN Increases Expression [28]
Tyrosine-protein phosphatase non-receptor type 5 (PTPN5) OT2H1KDK PTN5_HUMAN Decreases Expression [28]
Epithelial membrane protein 1 (EMP1) OTSZHUHQ EMP1_HUMAN Increases Expression [28]
Fibroblast growth factor 8 (FGF8) OTFU0IUW FGF8_HUMAN Decreases Expression [28]
Proteinase-activated receptor 2 (F2RL1) OTMRMJ8N PAR2_HUMAN Increases Expression [28]
Cadherin-8 (CDH8) OTS3SRZ6 CADH8_HUMAN Decreases Expression [28]
Homeobox protein DLX-6 (DLX6) OT0FIJHY DLX6_HUMAN Decreases Expression [28]
Transcription factor SOX-10 (SOX10) OTF25ULQ SOX10_HUMAN Increases Expression [28]
Neurotrypsin (PRSS12) OT1MYL3L NETR_HUMAN Increases Expression [28]
Claudin-6 (CLDN6) OTEN8ID2 CLD6_HUMAN Increases Expression [28]
Transcription factor SOX-8 (SOX8) OTEJXYZM SOX8_HUMAN Increases Expression [28]
Potassium channel subfamily K member 10 (KCNK10) OT93GC7V KCNKA_HUMAN Decreases Expression [28]
Inhibin beta E chain (INHBE) OTOI2NYG INHBE_HUMAN Increases Expression [28]
Myelin proteolipid protein (PLP1) OT8CM9CX MYPR_HUMAN Increases Expression [28]
Synaptosomal-associated protein 25 (SNAP25) OTUIQ81Q SNP25_HUMAN Increases Expression [28]
Protein S100-A10 (S100A10) OTI71243 S10AA_HUMAN Increases Expression [28]
Somatostatin (SST) OTY75GQH SMS_HUMAN Increases Expression [28]
Rho-related GTP-binding protein RhoE (RND3) OTXMXPIH RND3_HUMAN Increases Expression [28]
Neurocalcin-delta (NCALD) OTJZ8UEL NCALD_HUMAN Decreases Expression [28]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 (GNG11) OTHIXBGW GBG11_HUMAN Increases Expression [28]
Rho-related GTP-binding protein RhoB (RHOB) OTHQFQF7 RHOB_HUMAN Increases Expression [28]
Small ribosomal subunit protein eS24 (RPS24) OTSNKIL5 RS24_HUMAN Increases Expression [28]
Large ribosomal subunit protein eL31 (RPL31) OTV9E1OE RL31_HUMAN Decreases Expression [28]
Iroquois-class homeodomain protein IRX-1 (IRX1) OT0ZN9EJ IRX1_HUMAN Increases Expression [28]
Iroquois-class homeodomain protein IRX-3 (IRX3) OTLJ48FG IRX3_HUMAN Increases Expression [28]
Fractalkine (CX3CL1) OTPLGI0E X3CL1_HUMAN Increases Expression [28]
Reelin (RELN) OTLKMW1O RELN_HUMAN Increases Expression [28]
ETS-related transcription factor Elf-3 (ELF3) OTUTLEQO ELF3_HUMAN Increases Expression [28]
Protein delta homolog 1 (DLK1) OTE1VLNB DLK1_HUMAN Decreases Expression [28]
4-aminobutyrate aminotransferase, mitochondrial (ABAT) OTXAGR7J GABT_HUMAN Increases Expression [28]
Single-stranded DNA-binding protein 2 (SSBP2) OTYG1G80 SSBP2_HUMAN Decreases Expression [28]
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) OTRWGNBF LACTB_HUMAN Increases Expression [28]
Matrix-remodeling-associated protein 7 (MXRA7) OTVQLYIY MXRA7_HUMAN Decreases Expression [28]
Low-density lipoprotein receptor-related protein 2 (LRP2) OTZ6W681 LRP2_HUMAN Decreases Expression [28]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B) OTSFVC82 2ABB_HUMAN Decreases Expression [28]
Cyclin-dependent kinase 6 (CDK6) OTR95N0X CDK6_HUMAN Increases Expression [28]
Norrin (NDP) OTGDJ4US NDP_HUMAN Decreases Expression [28]
Sorbitol dehydrogenase (SORD) OTC44CR6 DHSO_HUMAN Decreases Expression [28]
Sodium channel protein type 7 subunit alpha (SCN7A) OTK05PXY SCN7A_HUMAN Decreases Expression [28]
Large neutral amino acids transporter small subunit 1 (SLC7A5) OT2WPVXD LAT1_HUMAN Increases Expression [28]
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) OTFP7AA8 PFKAP_HUMAN Increases Expression [28]
POU domain, class 5, transcription factor 1 (POU5F1) OTDHHN7O PO5F1_HUMAN Increases Expression [28]
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1) OTEUYEW6 ROR1_HUMAN Increases Expression [28]
Contactin-2 (CNTN2) OTQG9W7C CNTN2_HUMAN Decreases Expression [28]
Pro-neuregulin-1, membrane-bound isoform (NRG1) OTZO6F1X NRG1_HUMAN Decreases Expression [28]
Desmocollin-2 (DSC2) OTODVH8K DSC2_HUMAN Increases Expression [28]
A-kinase anchor protein 12 (AKAP12) OTCVRDDX AKA12_HUMAN Decreases Expression [28]
Paired box protein Pax-2 (PAX2) OTKP1N8F PAX2_HUMAN Increases Expression [28]
Dystonin (DST) OTHZBM4X DYST_HUMAN Decreases Expression [28]
POU domain, class 3, transcription factor 1 (POU3F1) OTYARA94 PO3F1_HUMAN Decreases Expression [28]
Histone-lysine N-methyltransferase MECOM (MECOM) OTP983W8 MECOM_HUMAN Decreases Expression [28]
Transducin-like enhancer protein 4 (TLE4) OT4QEH6T TLE4_HUMAN Decreases Expression [28]
Collagen alpha-1(XIV) chain (COL14A1) OTLNJ13O COEA1_HUMAN Increases Expression [28]
Aldehyde oxidase (AOX1) OT2FZP6H AOXA_HUMAN Decreases Expression [28]
Myocyte-specific enhancer factor 2C (MEF2C) OTZGF1Y5 MEF2C_HUMAN Increases Expression [28]
Putative POU domain, class 5, transcription factor 1B (POU5F1B) OT0FKQ51 P5F1B_HUMAN Increases Expression [28]
Protein CBFA2T1 (RUNX1T1) OT30DED5 MTG8_HUMAN Increases Expression [28]
Voltage-dependent L-type calcium channel subunit beta-2 (CACNB2) OT53K8W2 CACB2_HUMAN Decreases Expression [28]
3',5'-cyclic-AMP phosphodiesterase 4D (PDE4D) OT1RWFV0 PDE4D_HUMAN Increases Expression [28]
Neuroblast differentiation-associated protein AHNAK (AHNAK) OT6KH1WG AHNK_HUMAN Increases Expression [28]
Divergent protein kinase domain 1C (DIPK1C) OT4POSL2 DIK1C_HUMAN Decreases Expression [28]
Cingulin-like protein 1 (CGNL1) OTRE9DGT CGNL1_HUMAN Increases Expression [28]
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3GAL1) OTFCO8QX SIA4A_HUMAN Increases Expression [28]
Forkhead box protein O1 (FOXO1) OTPJRB6D FOXO1_HUMAN Increases Expression [28]
Contactin-1 (CNTN1) OT7RNPEY CNTN1_HUMAN Increases Expression [28]
Forkhead box protein C1 (FOXC1) OTOWZGYO FOXC1_HUMAN Increases Expression [28]
Glutamate receptor ionotropic, kainate 3 (GRIK3) OTX6K345 GRIK3_HUMAN Decreases Expression [28]
Rho GTPase-activating protein 5 (ARHGAP5) OTOQELUN RHG05_HUMAN Decreases Expression [28]
Platelet-activating factor acetylhydrolase (PLA2G7) OT6H6AMO PAFA_HUMAN Increases Expression [28]
Dual specificity protein phosphatase 4 (DUSP4) OT6WAO12 DUS4_HUMAN Decreases Expression [28]
RE1-silencing transcription factor (REST) OTLL92LQ REST_HUMAN Increases Expression [28]
BMP and activin membrane-bound inhibitor homolog (BAMBI) OTCEJ8W5 BAMBI_HUMAN Increases Expression [28]
Noggin (NOG) OTGRHHPG NOGG_HUMAN Increases Expression [28]
N-myc-interactor (NMI) OTYVG3NM NMI_HUMAN Increases Expression [28]
Zinc transporter ZIP6 (SLC39A6) OTCYF466 S39A6_HUMAN Decreases Expression [28]
Frizzled-5 (FZD5) OTXFFY56 FZD5_HUMAN Decreases Expression [28]
Protein phosphatase 1 regulatory subunit 1A (PPP1R1A) OTGTAGCV PPR1A_HUMAN Increases Expression [28]
Semaphorin-5A (SEMA5A) OTUOIOJV SEM5A_HUMAN Decreases Expression [28]
Cullin-3 (CUL3) OTDNOAPM CUL3_HUMAN Decreases Expression [28]
Cadherin-18 (CDH18) OTC06P9H CAD18_HUMAN Increases Expression [28]
Ras-related protein Rab-31 (RAB31) OTMLXQZ0 RAB31_HUMAN Increases Expression [28]
CD166 antigen (ALCAM) OTCO4LP7 CD166_HUMAN Increases Expression [28]
Laminin subunit gamma-2 (LAMC2) OTJMTM72 LAMC2_HUMAN Increases Expression [28]
Runt-related transcription factor 3 (RUNX3) OTITK1XD RUNX3_HUMAN Increases Expression [28]
Integrin alpha-9 (ITGA9) OTHN1IKA ITA9_HUMAN Increases Expression [28]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2) OTTUU92F ENPP2_HUMAN Increases Expression [28]
Krueppel-like factor 5 (KLF5) OT1ABI9N KLF5_HUMAN Increases Expression [28]
Collagen alpha-3(IX) chain (COL9A3) OTCUJOEK CO9A3_HUMAN Increases Expression [28]
Ras-related protein Rab-33A (RAB33A) OTHHU6WA RB33A_HUMAN Decreases Expression [28]
Septin-6 (SEPTIN6) OTIV9RTK SEPT6_HUMAN Increases Expression [28]
Tripartite motif-containing protein 14 (TRIM14) OTLQKUG0 TRI14_HUMAN Increases Expression [28]
Transcription factor E2F2 (E2F2) OTO75RM7 E2F2_HUMAN Decreases Expression [28]
Frizzled-2 (FZD2) OT952ML1 FZD2_HUMAN Decreases Expression [28]
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (PDE3A) OTKUW1WT PDE3A_HUMAN Increases Expression [28]
Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3) OT7M67WT GALT3_HUMAN Increases Expression [28]
Protein disulfide-isomerase A5 (PDIA5) OT76ZSX5 PDIA5_HUMAN Increases Expression [28]
Inositol 1,4,5-trisphosphate receptor type 2 (ITPR2) OTPHGZ19 ITPR2_HUMAN Increases Expression [28]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Increases Expression [28]
Metabotropic glutamate receptor 3 (GRM3) OTJFGE9S GRM3_HUMAN Decreases Expression [28]
AT-rich interactive domain-containing protein 5B (ARID5B) OTUQ4CQY ARI5B_HUMAN Increases Expression [28]
Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4) OTTDCUAO NFAC4_HUMAN Decreases Expression [28]
Opioid-binding protein/cell adhesion molecule (OPCML) OT93PQ6Y OPCM_HUMAN Increases Expression [28]
Uncharacterized protein KIAA0040 (KIAA0040) OT27EBY3 K0040_HUMAN Increases Expression [28]
Ras GTPase-activating protein 2 (RASA2) OTL06RG2 RASA2_HUMAN Decreases Expression [28]
Ankyrin repeat domain-containing protein 1 (ANKRD1) OTHJ7JV9 ANKR1_HUMAN Increases Expression [28]
Ephrin type-A receptor 7 (EPHA7) OT3VC211 EPHA7_HUMAN Increases Expression [28]
Angiopoietin-1 (ANGPT1) OTVZ1NG3 ANGP1_HUMAN Increases Expression [28]
Ryanodine receptor 3 (RYR3) OT4EHIP4 RYR3_HUMAN Decreases Expression [28]
SH2 domain-containing adapter protein B (SHB) OTF2HSC0 SHB_HUMAN Increases Expression [28]
Homeobox protein SIX1 (SIX1) OT70YYWM SIX1_HUMAN Increases Expression [28]
ALX homeobox protein 1 (ALX1) OTZVARA5 ALX1_HUMAN Increases Expression [28]
Myosin light chain kinase, smooth muscle (MYLK) OT78QB4A MYLK_HUMAN Decreases Expression [28]
Metallophosphoesterase MPPED2 (MPPED2) OT7XLMJ6 MPPD2_HUMAN Decreases Expression [28]
Mothers against decapentaplegic homolog 2 (SMAD2) OTC6VB4K SMAD2_HUMAN Decreases Expression [28]
Nuclear factor erythroid 2-related factor 2 (NFE2L2) OT0HENJ5 NF2L2_HUMAN Increases Expression [28]
Insulin-like growth factor-binding protein 7 (IGFBP7) OT1D416P IBP7_HUMAN Increases Expression [28]
Laminin subunit alpha-4 (LAMA4) OTHI7TA0 LAMA4_HUMAN Increases Expression [28]
Exostosin-1 (EXT1) OTRPALJK EXT1_HUMAN Decreases Expression [28]
Cyclin-G2 (CCNG2) OTII38K2 CCNG2_HUMAN Decreases Expression [28]
Prostasin (PRSS8) OT5KLL35 PRSS8_HUMAN Increases Expression [28]
Gamma-interferon-inducible protein 16 (IFI16) OT4SPU0U IF16_HUMAN Increases Expression [28]
Melanoma-derived growth regulatory protein (MIA) OTG5FN5S MIA_HUMAN Increases Expression [28]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Increases Expression [28]
Dual specificity protein phosphatase 5 (DUSP5) OTH96RA7 DUS5_HUMAN Increases Expression [28]
NADP-dependent malic enzyme, mitochondrial (ME3) OT3XMLYG MAON_HUMAN Decreases Expression [28]
Reticulon-1 (RTN1) OTCX1SMK RTN1_HUMAN Decreases Expression [28]
Receptor-type tyrosine-protein phosphatase O (PTPRO) OTFLKWOY PTPRO_HUMAN Decreases Expression [28]
Tumor protein D53 (TPD52L1) OTSA6U0I TPD53_HUMAN Increases Expression [28]
Protein inscuteable homolog (INSC) OTP16ERR INSC_HUMAN Increases Expression [28]
Inverted formin-2 (INF2) OT8ZM13C INF2_HUMAN Increases Expression [28]
MHC class I polypeptide-related sequence B (MICB) OTS2DVDW MICB_HUMAN Increases Expression [28]
Centrosomal protein kizuna (KIZ) OT5VCKSM KIZ_HUMAN Decreases Expression [28]
UPF0561 protein C2orf68 (C2ORF68) OTNNFK6R CB068_HUMAN Decreases Expression [28]
FH1/FH2 domain-containing protein 3 (FHOD3) OT1WUBQX FHOD3_HUMAN Decreases Expression [28]
Complement component receptor 1-like protein (CR1L) OTX3KR7U CR1L_HUMAN Increases Expression [28]
Transcription factor RFX4 (RFX4) OTYFRHPA RFX4_HUMAN Increases Expression [28]
Cell cycle control protein 50B (TMEM30B) OTNSBH84 CC50B_HUMAN Increases Expression [28]
Transcription factor Sp6 (SP6) OTRAB1PN SP6_HUMAN Increases Expression [28]
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2) OTCH86VF AL1L2_HUMAN Increases Expression [28]
Synaptic vesicle glycoprotein 2C (SV2C) OTIH108W SV2C_HUMAN Increases Expression [28]
Uncharacterized protein C8orf34 (C8ORF34) OTXCTHDG CH034_HUMAN Increases Expression [28]
Cell adhesion molecule-related/down-regulated by oncogenes (CDON) OT81X593 CDON_HUMAN Increases Expression [28]
Extracellular tyrosine-protein kinase PKDCC (PKDCC) OTVXJR26 PKDCC_HUMAN Increases Expression [28]
Raftlin-2 (RFTN2) OT4WYAD9 RFTN2_HUMAN Increases Expression [28]
Seizure protein 6 homolog (SEZ6) OTCD8K5D SEZ6_HUMAN Increases Expression [28]
Acyl-coenzyme A synthetase ACSM3, mitochondrial (ACSM3) OT0AE1IV ACSM3_HUMAN Increases Expression [28]
Pleckstrin homology-like domain family A member 2 (PHLDA2) OTMV9DPP PHLA2_HUMAN Increases Expression [28]
Rho GTPase-activating protein 15 (ARHGAP15) OT9CKHDC RHG15_HUMAN Decreases Expression [28]
Fibulin-7 (FBLN7) OT1XRDP6 FBLN7_HUMAN Decreases Expression [28]
Cordon-bleu protein-like 1 (COBLL1) OTQFN1TC COBL1_HUMAN Increases Expression [28]
Protein Largen (PRR16) OTG4TEGR LARGN_HUMAN Increases Expression [28]
TPA-induced transmembrane protein (C3ORF52) OTI0JAT8 TTMP_HUMAN Increases Expression [28]
FRAS1-related extracellular matrix protein 1 (FREM1) OTMHRV87 FREM1_HUMAN Increases Expression [28]
Solute carrier family 25 member 53 (SLC25A53) OTNHVTOB S2553_HUMAN Decreases Expression [28]
Protein BEX5 (BEX5) OTZ2RB6L BEX5_HUMAN Increases Expression [28]
Protein phosphatase 1J (PPM1J) OTM6GDJJ PPM1J_HUMAN Increases Expression [28]
Uncharacterized protein KIAA1755 (KIAA1755) OT1FCGEW K1755_HUMAN Increases Expression [28]
Collectin-12 (COLEC12) OTIQTK9G COL12_HUMAN Increases Expression [28]
EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT) OT4A2A8P EOGT_HUMAN Increases Expression [28]
Neurite extension and migration factor (NEXMIF) OT576F40 NEXMI_HUMAN Decreases Expression [28]
Uncharacterized protein C6orf141 (C6ORF141) OTUS3SIQ CF141_HUMAN Decreases Expression [28]
Centrosomal protein of 85 kDa-like (CEP85L) OTSHJFOT CE85L_HUMAN Increases Expression [28]
Transmembrane protein 170B (TMEM170B) OT4AS8RJ T170B_HUMAN Decreases Expression [28]
Protein FAM162B (FAM162B) OTZ31RP5 F162B_HUMAN Increases Expression [28]
LINE-1 type transposase domain-containing protein 1 (L1TD1) OTB2W20Y LITD1_HUMAN Increases Expression [28]
KN motif and ankyrin repeat domain-containing protein 4 (KANK4) OT5WC0Q8 KANK4_HUMAN Increases Expression [28]
Transcription factor HES-5 (HES5) OTW7JEHV HES5_HUMAN Decreases Expression [28]
PX domain-containing protein 1 (PXDC1) OTQUA3TG PXDC1_HUMAN Increases Expression [28]
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3) OTGQV0CU BIG3_HUMAN Decreases Expression [28]
Glycoprotein endo-alpha-1,2-mannosidase-like protein (MANEAL) OT248IN0 MANEL_HUMAN Increases Expression [28]
G kinase-anchoring protein 1 (GKAP1) OTHZRJ56 GKAP1_HUMAN Decreases Expression [28]
Myomegalin (PDE4DIP) OTS15WNF MYOME_HUMAN Increases Expression [28]
Uncharacterized protein C1orf53 (C1ORF53) OTQTOA4D CA053_HUMAN Decreases Expression [28]
Scm-like with four MBT domains protein 2 (SFMBT2) OTZQT61Q SMBT2_HUMAN Increases Expression [28]
DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) OTLEF5TY DC122_HUMAN Decreases Expression [28]
Proteasome adapter and scaffold protein ECM29 (ECPAS) OT1C0KOI ECM29_HUMAN Decreases Expression [28]
B box and SPRY domain-containing protein (BSPRY) OTVVZRKY BSPRY_HUMAN Increases Expression [28]
Meteorin-like protein (METRNL) OTB0DDL0 METRL_HUMAN Increases Expression [28]
Metalloreductase STEAP3 (STEAP3) OTS9GZK5 STEA3_HUMAN Increases Expression [28]
E3 ubiquitin-protein ligase RNF43 (RNF43) OT2R9YDP RNF43_HUMAN Increases Expression [28]
LIM/homeobox protein Lhx8 (LHX8) OT0DFL7C LHX8_HUMAN Increases Expression [28]
Transcription factor Sp5 (SP5) OT4HUP9B SP5_HUMAN Increases Expression [28]
Tyrosine-protein kinase STYK1 (STYK1) OT61CSU7 STYK1_HUMAN Increases Expression [28]
Volume-regulated anion channel subunit LRRC8E (LRRC8E) OTUZTANF LRC8E_HUMAN Increases Expression [28]
MFS-type transporter SLC18B1 (SLC18B1) OT9EVUN1 S18B1_HUMAN Increases Expression [28]
TMF-regulated nuclear protein 1 (TRNP1) OTYYV8LN TRNP1_HUMAN Increases Expression [28]
Epithelial splicing regulatory protein 1 (ESRP1) OTNCS4SL ESRP1_HUMAN Increases Expression [28]
Cdc42 effector protein 5 (CDC42EP5) OTQQDUCD BORG3_HUMAN Increases Expression [28]
Protein C3orf33 (C3ORF33) OTP8MJAN CC033_HUMAN Decreases Expression [28]
DENN domain-containing protein 1B (DENND1B) OT3VCNPE DEN1B_HUMAN Decreases Expression [28]
Phospholipase B-like 1 (PLBD1) OTHYEB4W PLBL1_HUMAN Increases Expression [28]
Polypeptide N-acetylgalactosaminyltransferase 18 (GALNT18) OTKIIELC GLT18_HUMAN Increases Expression [28]
Volume-regulated anion channel subunit LRRC8B (LRRC8B) OTH2LMJ4 LRC8B_HUMAN Decreases Expression [28]
Transmembrane protein 154 (TMEM154) OTEAFLJE TM154_HUMAN Increases Expression [28]
Transmembrane protein 88 (TMEM88) OTA96YEL TMM88_HUMAN Decreases Expression [28]
Interleukin-27 receptor subunit alpha (IL27RA) OTSQBAKI I27RA_HUMAN Increases Expression [28]
Lactase-like protein (LCTL) OTN36T21 LCTL_HUMAN Decreases Expression [28]
Layilin (LAYN) OT9A9Q1X LAYN_HUMAN Increases Expression [28]
ALK and LTK ligand 2 (ALKAL2) OTTLHL64 ALKL2_HUMAN Increases Expression [28]
Inactive serine protease PAMR1 (PAMR1) OT83ZH5U PAMR1_HUMAN Decreases Expression [28]
Nephronectin (NPNT) OTFZAO1G NPNT_HUMAN Increases Expression [28]
Interleukin-20 receptor subunit beta (IL20RB) OTHFXK95 I20RB_HUMAN Increases Expression [28]
R-spondin-2 (RSPO2) OT3HHXU0 RSPO2_HUMAN Decreases Expression [28]
Transmembrane channel-like protein 5 (TMC5) OTO5D86M TMC5_HUMAN Increases Expression [28]
Transmembrane protein 64 (TMEM64) OTO9IDFD TMM64_HUMAN Increases Expression [28]
Nesprin-3 (SYNE3) OTEOJBYB SYNE3_HUMAN Increases Expression [28]
Metastasis-associated in colon cancer protein 1 (MACC1) OTV3DLX0 MACC1_HUMAN Increases Expression [28]
Zinc finger protein basonuclin-2 (BNC2) OTU22H9Z BNC2_HUMAN Increases Expression [28]
Lysophospholipid acyltransferase 1 (MBOAT1) OT4XR6TE MBOA1_HUMAN Increases Expression [28]
FYVE, RhoGEF and PH domain-containing protein 5 (FGD5) OT5VIRP2 FGD5_HUMAN Increases Expression [28]
Solute carrier organic anion transporter family member 4C1 (SLCO4C1) OTVILUUN SO4C1_HUMAN Increases Expression [28]
RNA-binding protein with multiple splicing 2 (RBPMS2) OTY24L1F RBPS2_HUMAN Increases Expression [28]
Leucine-rich repeat-containing protein 55 (LRRC55) OT8LQI1W LRC55_HUMAN Decreases Expression [28]
RNA-binding protein 43 (RBM43) OTANIFBG RBM43_HUMAN Increases Expression [28]
Acyl-CoA dehydrogenase family member 11 (ACAD11) OT3T9HAX ACD11_HUMAN Increases Expression [28]
BTB/POZ domain-containing protein KCTD1 (KCTD1) OT89U5MB KCTD1_HUMAN Increases Expression [28]
Mediator of RNA polymerase II transcription subunit 13-like (MED13L) OTSP1W0F MD13L_HUMAN Increases Expression [28]
Eukaryotic translation initiation factor 3 subunit M (EIF3M) OTVWEV60 EIF3M_HUMAN Decreases Expression [28]
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (LINGO2) OT3N88Q1 LIGO2_HUMAN Increases Expression [28]
CXXC-type zinc finger protein 5 (CXXC5) OTGCN3B5 CXXC5_HUMAN Increases Expression [28]
Carbohydrate sulfotransferase 15 (CHST15) OTNTM2SP CHSTF_HUMAN Increases Expression [28]
Monocarboxylate transporter 14 (SLC16A14) OTUGDEUV MOT14_HUMAN Decreases Expression [28]
C-myc promoter-binding protein (DENND4A) OT8FFZ29 MYCPP_HUMAN Increases Expression [28]
E3 ubiquitin-protein ligase RNF144B (RNF144B) OTN7FCDE R144B_HUMAN Increases Expression [28]
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein (BNIPL) OTDHOA74 BNIPL_HUMAN Increases Expression [28]
Cilia- and flagella-associated protein 91 (CFAP91) OTVDRDGX CFA91_HUMAN Decreases Expression [28]
Transmembrane protein 144 (TMEM144) OT66EYSR TM144_HUMAN Increases Expression [28]
Uncharacterized protein C11orf96 (C11ORF96) OTEQU0V7 CK096_HUMAN Increases Expression [28]
Amphoterin-induced protein 2 (AMIGO2) OTPAIT1O AMGO2_HUMAN Increases Expression [28]
Armadillo-like helical domain-containing protein 4 (ARMH4) OT25GBJM ARMD4_HUMAN Decreases Expression [28]
Sodium/hydrogen exchanger 9B2 (SLC9B2) OTZVOY8T SL9B2_HUMAN Decreases Expression [28]
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (MAGI2) OTXDDKZS MAGI2_HUMAN Increases Expression [28]
Regulating synaptic membrane exocytosis protein 1 (RIMS1) OT10T7CK RIMS1_HUMAN Increases Expression [28]
Inter-alpha-trypsin inhibitor heavy chain H5 (ITIH5) OTP46PZM ITIH5_HUMAN Increases Expression [28]
Protein FAM124A (FAM124A) OTF1DJX0 F124A_HUMAN Decreases Expression [28]
Glucocorticoid-induced transcript 1 protein (GLCCI1) OTU0R1CU GLCI1_HUMAN Decreases Expression [28]
Four-jointed box protein 1 (FJX1) OT8SVTSS FJX1_HUMAN Decreases Expression [28]
Catechol O-methyltransferase domain-containing protein 1 (COMTD1) OTLQJTBI CMTD1_HUMAN Increases Expression [28]
SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) OTHH06X8 SESD1_HUMAN Decreases Expression [28]
Juxtaposed with another zinc finger protein 1 (JAZF1) OTXTYSYD JAZF1_HUMAN Increases Expression [28]
Myotubularin-related protein 13 (SBF2) OTBB8NO8 MTMRD_HUMAN Increases Expression [28]
Ras association domain-containing protein 3 (RASSF3) OT4V9SRK RASF3_HUMAN Increases Expression [28]
E3 ubiquitin-protein ligase TRIM69 (TRIM69) OTTEGTRD TRI69_HUMAN Increases Expression [28]
Probable D-lactate dehydrogenase, mitochondrial (LDHD) OTTKLJWP LDHD_HUMAN Increases Expression [28]
Chondroitin sulfate synthase 1 (CHSY1) OTB1XSSF CHSS1_HUMAN Increases Expression [28]
Dynein regulatory complex protein 11 (IQCA1) OTFBF3FI DRC11_HUMAN Increases Expression [28]
Protein phosphatase 1 regulatory subunit 3B (PPP1R3B) OTVCRXEZ PPR3B_HUMAN Increases Expression [28]
Collagen alpha-1(XXIII) chain (COL23A1) OTYE0N3I CONA1_HUMAN Increases Expression [28]
Testis development-related protein (TDRP) OTEFLMGF TDRP_HUMAN Increases Expression [28]
Podoplanin (PDPN) OTBUV19I PDPN_HUMAN Increases Expression [28]
Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B) OTN6FKCB PRGC2_HUMAN Increases Expression [28]
Rab11 family-interacting protein 4 (RAB11FIP4) OTIGHER7 RFIP4_HUMAN Increases Expression [28]
Inactive tyrosine-protein kinase PRAG1 (PRAG1) OTV83SGI PRAG1_HUMAN Increases Expression [28]
Purine nucleoside phosphorylase LACC1 (LACC1) OT4SBHI8 LACC1_HUMAN Increases Expression [28]
LysM and putative peptidoglycan-binding domain-containing protein 2 (LYSMD2) OT1VCC2M LYSM2_HUMAN Increases Expression [28]
Proline-rich protein 15 (PRR15) OTJHSY8G PRR15_HUMAN Increases Expression [28]
Neuron navigator 3 (NAV3) OT97M1TR NAV3_HUMAN Increases Expression [28]
Immunoglobulin superfamily DCC subclass member 3 (IGDCC3) OTGR1KA4 IGDC3_HUMAN Increases Expression [28]
Sodium channel subunit beta-4 (SCN4B) OT3JSUWO SCN4B_HUMAN Increases Expression [28]
Sphingosine-1-phosphate phosphatase 2 (SGPP2) OTIDIJCR SGPP2_HUMAN Increases Expression [28]
Uncharacterized protein C12orf56 (C12ORF56) OT4KDTKF CL056_HUMAN Increases Expression [28]
Solute carrier family 35 member F2 (SLC35F2) OTSAD4EQ S35F2_HUMAN Increases Expression [28]
Transcription factor Sp8 (SP8) OTLCMPKH SP8_HUMAN Decreases Expression [28]
Procollagen galactosyltransferase 2 (COLGALT2) OTV9EDZB GT252_HUMAN Decreases Expression [28]
Ras and EF-hand domain-containing protein (RASEF) OTGSAM2E RASEF_HUMAN Increases Expression [28]
Myocardin (MYOCD) OTSJNHTH MYCD_HUMAN Increases Expression [28]
Protein SIX6OS1 (C14ORF39) OTFKQ6HO S6OS1_HUMAN Decreases Expression [28]
Neuroligin-1 (NLGN1) OTGHRRFQ NLGN1_HUMAN Decreases Expression [28]
Protein FAM43A (FAM43A) OT5RPQRE FA43A_HUMAN Increases Expression [28]
Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1L) OTVLWW9T GPD1L_HUMAN Increases Expression [28]
ELMO domain-containing protein 1 (ELMOD1) OT0WRVJC ELMD1_HUMAN Increases Expression [28]
Mucin-15 (MUC15) OT3PQT6L MUC15_HUMAN Increases Expression [28]
Rho GTPase-activating protein 18 (ARHGAP18) OTYMJP6H RHG18_HUMAN Increases Expression [28]
MICAL-like protein 1 (MICALL1) OTHG9B2U MILK1_HUMAN Increases Expression [28]
Protein phosphatase Mn(2+)-dependent 1K (PPM1K) OTNZ4N4E PPM1K_HUMAN Increases Expression [28]
Thioredoxin domain-containing protein 3 (NME8) OT4RULP5 TXND3_HUMAN Increases Expression [28]
Inactive carboxypeptidase-like protein X2 (CPXM2) OTDJNOTR CPXM2_HUMAN Increases Expression [28]
Secreted frizzled-related protein 1 (SFRP1) OT0U9G41 SFRP1_HUMAN Decreases Expression [28]
Protein limb expression 1 homolog (LIX1) OT1CPNCC LIX1_HUMAN Decreases Expression [28]
RING finger protein 175 (RNF175) OTKAZ8ZW RN175_HUMAN Decreases Expression [28]
Reprimo-like protein (RPRML) OTPOESFN RPRML_HUMAN Increases Expression [28]
Serine/threonine-protein kinase DCLK2 (DCLK2) OTT0AU1C DCLK2_HUMAN Decreases Expression [28]
Ephexin-1 (NGEF) OT9QUXJ3 NGEF_HUMAN Increases Expression [28]
Eukaryotic translation initiation factor 4E type 3 (EIF4E3) OTTWVS2R IF4E3_HUMAN Decreases Expression [28]
E3 ubiquitin-protein ligase RNF182 (RNF182) OT08FLHZ RN182_HUMAN Decreases Expression [28]
CUGBP Elav-like family member 5 (CELF5) OT02OG9N CELF5_HUMAN Decreases Expression [28]
Protocadherin-20 (PCDH20) OTFSNRXK PCD20_HUMAN Increases Expression [28]
Leucine-rich repeat-containing protein 17 (LRRC17) OT3NZSX3 LRC17_HUMAN Increases Expression [28]
APC membrane recruitment protein 2 (AMER2) OTA1Q07C AMER2_HUMAN Increases Expression [28]
BMP-binding endothelial regulator protein (BMPER) OTBYON4H BMPER_HUMAN Increases Expression [28]
V-type proton ATPase subunit d 2 (ATP6V0D2) OTMOZJO0 VA0D2_HUMAN Increases Expression [28]
Tetratricopeptide repeat protein 29 (TTC29) OT37KCUL TTC29_HUMAN Increases Expression [28]
Fibronectin type III domain-containing protein 5 (FNDC5) OT5CSK9X FNDC5_HUMAN Decreases Expression [28]
Transmembrane protein 178A (TMEM178A) OTQZY4NP T178A_HUMAN Decreases Expression [28]
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) OTBIN5IP SCPDL_HUMAN Decreases Expression [28]
Carbohydrate sulfotransferase 4 (CHST4) OTESMIW5 CHST4_HUMAN Increases Expression [28]
Potassium voltage-gated channel subfamily H member 5 (KCNH5) OTVAHEAQ KCNH5_HUMAN Decreases Expression [28]
Protein FAM13C (FAM13C) OTVAGUOV FA13C_HUMAN Increases Expression [28]
Zinc finger protein GLIS3 (GLIS3) OTBC960E GLIS3_HUMAN Decreases Expression [28]
Neuron navigator 1 (NAV1) OT667KTL NAV1_HUMAN Decreases Expression [28]
Nesprin-1 (SYNE1) OTSBSLUH SYNE1_HUMAN Increases Expression [28]
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (B3GNT7) OT8UTTXF B3GN7_HUMAN Increases Expression [28]
Interleukin-17 receptor D (IL17RD) OTKD9XST I17RD_HUMAN Decreases Expression [28]
Bestrophin-4 (BEST4) OT6S406I BEST4_HUMAN Decreases Expression [28]
Semaphorin-6D (SEMA6D) OTU0UAZS SEM6D_HUMAN Decreases Expression [28]
Cell adhesion molecule 4 (CADM4) OT0TFMFE CADM4_HUMAN Decreases Expression [28]
Nuclear receptor coactivator 7 (NCOA7) OT2CNBOG NCOA7_HUMAN Decreases Expression [28]
LIM domain only protein 3 (LMO3) OTR7AJHN LMO3_HUMAN Decreases Expression [28]
Fibroblast growth factor-binding protein 3 (FGFBP3) OTWM1KCM FGFP3_HUMAN Increases Expression [28]
DEP domain-containing mTOR-interacting protein (DEPTOR) OTCBP1BT DPTOR_HUMAN Increases Expression [28]
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (HMGCLL1) OT9SQ5PU HMGC2_HUMAN Decreases Expression [28]
E3 ubiquitin-protein ligase LNX (LNX1) OTZWFMAZ LNX1_HUMAN Increases Expression [28]
Synaptoporin (SYNPR) OTNCJ9L0 SYNPR_HUMAN Increases Expression [28]
Fez family zinc finger protein 2 (FEZF2) OTU4TXIW FEZF2_HUMAN Decreases Expression [28]
Transmembrane protein 163 (TMEM163) OTCT1Y1L TM163_HUMAN Decreases Expression [28]
E3 ubiquitin-protein ligase RNF217 (RNF217) OTAX91ES RN217_HUMAN Increases Expression [28]
Fibronectin type 3 and ankyrin repeat domains protein 1 (FANK1) OT5641YJ FANK1_HUMAN Decreases Expression [28]
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1) OTUTPVA9 PREX1_HUMAN Increases Expression [28]
Mucolipin-3 (MCOLN3) OTCRPRVS MCLN3_HUMAN Increases Expression [28]
Protocadherin Fat 3 (FAT3) OT3C6H8W FAT3_HUMAN Decreases Expression [28]
A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAMTS15) OTYB6JS3 ATS15_HUMAN Increases Expression [28]
A disintegrin and metalloproteinase with thrombospondin motifs 19 (ADAMTS19) OTEG5Q2G ATS19_HUMAN Increases Expression [28]
Grainyhead-like protein 3 homolog (GRHL3) OT1V4ZEH GRHL3_HUMAN Increases Expression [28]
Actin filament-associated protein 1-like 1 (AFAP1L1) OTWNTNDB AF1L1_HUMAN Increases Expression [28]
DENN domain-containing protein 1A (DENND1A) OTONDAA0 DEN1A_HUMAN Decreases Expression [28]
Serine/threonine-protein kinase 32A (STK32A) OTONYLYO ST32A_HUMAN Decreases Expression [28]
RelA-associated inhibitor (PPP1R13L) OTNCPLWE IASPP_HUMAN Increases Expression [28]
Protein prune homolog 2 (PRUNE2) OTGW2974 PRUN2_HUMAN Decreases Expression [28]
DEP domain-containing protein 1B (DEPDC1B) OTMVFOT1 DEP1B_HUMAN Decreases Expression [28]
DDB1- and CUL4-associated factor 4 (DCAF4) OTQU0EUO DCAF4_HUMAN Increases Expression [28]
Pleckstrin homology-like domain family A member 1 (PHLDA1) OTFTWMIQ PHLA1_HUMAN Increases Expression [28]
PH-interacting protein (PHIP) OTZY806Z PHIP_HUMAN Decreases Expression [28]
Cholesterol transporter ABCA5 (ABCA5) OT4B9D92 ABCA5_HUMAN Decreases Expression [28]
Secretogranin-3 (SCG3) OTUYSV2S SCG3_HUMAN Increases Expression [28]
Adhesion G-protein coupled receptor V1 (ADGRV1) OTLVXHHP AGRV1_HUMAN Decreases Expression [28]
Connector enhancer of kinase suppressor of ras 2 (CNKSR2) OTAGERJ2 CNKR2_HUMAN Decreases Expression [28]
BRI3-binding protein (BRI3BP) OTWCFPRM BRI3B_HUMAN Increases Expression [28]
Nanos homolog 1 (NANOS1) OT3UNZZY NANO1_HUMAN Decreases Expression [28]
E3 ubiquitin-protein ligase MYLIP (MYLIP) OTL0PFGV MYLIP_HUMAN Increases Expression [28]
Jun dimerization protein 2 (JDP2) OTW35WKX JDP2_HUMAN Increases Expression [28]
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2) OTBXYFRH ARAP2_HUMAN Increases Expression [28]
Transcription factor AP-2-beta (TFAP2B) OTR1T8E9 AP2B_HUMAN Increases Expression [28]
Protein FAM168A (FAM168A) OTDXQCS5 F168A_HUMAN Decreases Expression [28]
Transcription factor AP-2 gamma (TFAP2C) OTUDIW05 AP2C_HUMAN Increases Expression [28]
Secreted frizzled-related protein 3 (FRZB) OTTO3DPY SFRP3_HUMAN Decreases Expression [28]
Ras-responsive element-binding protein 1 (RREB1) OT62460U RREB1_HUMAN Increases Expression [28]
Hyaluronan synthase 2 (HAS2) OTTD3PAL HYAS2_HUMAN Increases Expression [28]
Coronin-2A (CORO2A) OTVK7PK3 COR2A_HUMAN Increases Expression [28]
Histone acetyltransferase KAT2B (KAT2B) OTWQITWK KAT2B_HUMAN Decreases Expression [28]
Protein kinase C-binding protein NELL1 (NELL1) OTF3TX3N NELL1_HUMAN Increases Expression [28]
Kinesin-associated protein 3 (KIFAP3) OT450PAO KIFA3_HUMAN Increases Expression [28]
BLOC-3 complex member HPS1 (HPS1) OTKS5I7T HPS1_HUMAN Increases Expression [28]
Deleted in azoospermia-like (DAZL) OTZMTD4R DAZL_HUMAN Decreases Expression [28]
Receptor-type tyrosine-protein phosphatase N2 (PTPRN2) OTL6SH28 PTPR2_HUMAN Decreases Expression [28]
Stathmin-2 (STMN2) OT0FUHLH STMN2_HUMAN Increases Expression [28]
Protein naked cuticle homolog 1 (NKD1) OTY3MO97 NKD1_HUMAN Increases Expression [28]
Protein TMEPAI (PMEPA1) OTY8Z9UF PMEPA_HUMAN Increases Expression [28]
Mitochondrial amidoxime reducing component 2 (MTARC2) OT8B6LVD MARC2_HUMAN Increases Expression [28]
Terminal nucleotidyltransferase 5B (TENT5B) OTO2P28B TET5B_HUMAN Increases Expression [28]
Copine-4 (CPNE4) OTTAGM5L CPNE4_HUMAN Increases Expression [28]
SPRY domain-containing SOCS box protein 4 (SPSB4) OTG9MLO4 SPSB4_HUMAN Increases Expression [28]
SOSS complex subunit B2 (NABP1) OTFTNFHW SOSB2_HUMAN Increases Expression [28]
Ras-related protein Rab-7b (RAB7B) OT60A0E9 RAB7B_HUMAN Increases Expression [28]
Transmembrane protein 125 (TMEM125) OTWF8MC1 TM125_HUMAN Increases Expression [28]
Claudin-23 (CLDN23) OTN5RV40 CLD23_HUMAN Increases Expression [28]
Transmembrane protein 18 (TMEM18) OT05YQ1E TMM18_HUMAN Decreases Expression [28]
Repulsive guidance molecule A (RGMA) OTZAMDO2 RGMA_HUMAN Decreases Expression [28]
SH3 domain-containing kinase-binding protein 1 (SH3KBP1) OTIUA60B SH3K1_HUMAN Increases Expression [28]
Serine/threonine-protein kinase Sgk3 (SGK3) OTQ6QO99 SGK3_HUMAN Increases Expression [28]
BTB/POZ domain-containing protein KCTD12 (KCTD12) OTPYKT4Z KCD12_HUMAN Increases Expression [28]
Endoplasmic reticulum resident protein 27 (ERP27) OTVMGE2H ERP27_HUMAN Increases Expression [28]
Polyadenylate-binding protein 5 (PABPC5) OTLUTQ02 PABP5_HUMAN Increases Expression [28]
Ras-related protein Rab-3C (RAB3C) OTFTJNGA RAB3C_HUMAN Increases Expression [28]
Elongator complex protein 4 (ELP4) OTP5GZ9V ELP4_HUMAN Decreases Expression [28]
Multivesicular body subunit 12A (MVB12A) OT3737K0 MB12A_HUMAN Decreases Expression [28]
CB1 cannabinoid receptor-interacting protein 1 (CNRIP1) OTXPWJ56 CNRP1_HUMAN Increases Expression [28]
Protein FAM89A (FAM89A) OTNASAXT FA89A_HUMAN Increases Expression [28]
Secreted frizzled-related protein 2 (SFRP2) OT8GZ0CA SFRP2_HUMAN Decreases Expression [28]
Transmembrane protein 169 (TMEM169) OTKXDYVC TM169_HUMAN Decreases Expression [28]
4-hydroxyphenylpyruvate dioxygenase-like protein (HPDL) OTW7D1SV HPDL_HUMAN Increases Expression [28]
Epithelial-stromal interaction protein 1 (EPSTI1) OT75I1UH ESIP1_HUMAN Increases Expression [28]
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) OTY5HZN5 LRIG1_HUMAN Decreases Expression [28]
Microtubule-associated protein 6 (MAP6) OTPUI00F MAP6_HUMAN Decreases Expression [28]
Coiled-coil domain-containing protein 136 (CCDC136) OTPOV391 CC136_HUMAN Decreases Expression [28]
Golgi-associated RAB2 interactor protein 1B (GARIN1B) OTWPN527 GAR1B_HUMAN Decreases Expression [28]
Phospholipase A and acyltransferase 5 (PLAAT5) OT9JFFO2 PLAT5_HUMAN Increases Expression [28]
Sushi domain-containing protein 3 (SUSD3) OTERJTUL SUSD3_HUMAN Increases Expression [28]
Guanine nucleotide exchange factor C9orf72 (C9ORF72) OT0WH38E CI072_HUMAN Decreases Expression [28]
Kremen protein 1 (KREMEN1) OTGJFSAC KREM1_HUMAN Increases Expression [28]
Transmembrane protein 74 (TMEM74) OT3IZBM0 TMM74_HUMAN Decreases Expression [28]
TOX high mobility group box family member 2 (TOX2) OT7RZRVK TOX2_HUMAN Decreases Expression [28]
Patched domain-containing protein 1 (PTCHD1) OTFDLU5S PTHD1_HUMAN Increases Expression [28]
Dachshund homolog 2 (DACH2) OT33KEUZ DACH2_HUMAN Increases Expression [28]
Chloride intracellular channel protein 6 (CLIC6) OTFMSU5U CLIC6_HUMAN Increases Expression [28]
Noelin-3 (OLFM3) OTBHPDTL NOE3_HUMAN Increases Expression [28]
Leucine-rich repeat-containing protein 3B (LRRC3B) OT9VDGPR LRC3B_HUMAN Decreases Expression [28]
Secretoglobin family 3A member 2 (SCGB3A2) OTB63PHR SG3A2_HUMAN Increases Expression [28]
VPS10 domain-containing receptor SorCS2 (SORCS2) OTBF3DYK SORC2_HUMAN Decreases Expression [28]
Rho GTPase-activating protein 7 (DLC1) OTP8LMCR RHG07_HUMAN Increases Expression [28]
DEP domain-containing protein 7 (DEPDC7) OT62C942 DEPD7_HUMAN Increases Expression [28]
Rab-3A-interacting protein (RAB3IP) OT3UPQAA RAB3I_HUMAN Decreases Expression [28]
Homeobox protein ARX (ARX) OTBGYH25 ARX_HUMAN Decreases Expression [28]
Lipase maturation factor 1 (LMF1) OTOL14ZD LMF1_HUMAN Increases Expression [28]
Doublesex- and mab-3-related transcription factor A2 (DMRTA2) OTWQR1M7 DMTA2_HUMAN Increases Expression [28]
Mucin-4 (MUC4) OTLT11V1 MUC4_HUMAN Increases Expression [28]
Glutamate decarboxylase 1 (GAD1) OT52Z39J DCE1_HUMAN Increases Expression [28]
Protein kinase C-binding protein NELL2 (NELL2) OTS4MJZ7 NELL2_HUMAN Decreases Expression [28]
Sphingosine 1-phosphate receptor 3 (S1PR3) OTXBIYO8 S1PR3_HUMAN Decreases Expression [28]
Krueppel-like factor 6 (KLF6) OTQY9S7F KLF6_HUMAN Increases Expression [28]
Fasciculation and elongation protein zeta-1 (FEZ1) OTWCXPRE FEZ1_HUMAN Decreases Expression [28]
Pituitary homeobox 2 (PITX2) OTWMXAOY PITX2_HUMAN Increases Expression [28]
Endothelial PAS domain-containing protein 1 (EPAS1) OTRE3O8U EPAS1_HUMAN Increases Expression [28]
Epidermal growth factor-like protein 8 (EGFL8) OTECTJ7K EGFL8_HUMAN Increases Expression [28]
Forkhead box protein C2 (FOXC2) OT83P1E0 FOXC2_HUMAN Increases Expression [28]
Cbp/p300-interacting transactivator 2 (CITED2) OT812TV7 CITE2_HUMAN Increases Expression [28]
Retinoic acid receptor responder protein 2 (RARRES2) OT1BJE8K RARR2_HUMAN Increases Expression [28]
Semaphorin-3C (SEMA3C) OTEGUY7F SEM3C_HUMAN Increases Expression [28]
Fermitin family homolog 1 (FERMT1) OT626PBA FERM1_HUMAN Increases Expression [28]
Synaptotagmin-11 (SYT11) OTLRTZEI SYT11_HUMAN Decreases Expression [28]
Brain-enriched guanylate kinase-associated protein (BEGAIN) OTT3UD2K BEGIN_HUMAN Decreases Expression [28]
Protein ABHD14A (ABHD14A) OT94GKE1 ABHEA_HUMAN Decreases Expression [28]
Ribonuclease P protein subunit p25 (RPP25) OTEN6QN7 RPP25_HUMAN Increases Expression [28]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1) OTJGE772 CHAC1_HUMAN Increases Expression [28]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ST6GALNAC5) OTH91ETM SIA7E_HUMAN Decreases Expression [28]
Cell cycle regulator of non-homologous end joining (CYREN) OT5ZL00R CYREN_HUMAN Decreases Expression [28]
Brother of CDO (BOC) OTXBCY9W BOC_HUMAN Increases Expression [28]
RNA-binding protein 24 (RBM24) OTQI1AR1 RBM24_HUMAN Decreases Expression [28]
Receptor for retinol uptake STRA6 (STRA6) OT2IDF27 STRA6_HUMAN Increases Expression [28]
Sphingosine-1-phosphate phosphatase 1 (SGPP1) OT9X54CQ SGPP1_HUMAN Increases Expression [28]
Sal-like protein 3 (SALL3) OTJ2LZKQ SALL3_HUMAN Decreases Expression [28]
Oxysterol-binding protein-related protein 10 (OSBPL10) OT0TFMBE OSB10_HUMAN Increases Expression [28]
Complement C1q tumor necrosis factor-related protein 4 (C1QTNF4) OTHD4Y9D C1QT4_HUMAN Decreases Expression [28]
Microtubule-associated proteins 1A/1B light chain 3C (MAP1LC3C) OTM4ECDK MLP3C_HUMAN Increases Expression [28]
R-spondin-3 (RSPO3) OTZK8GDS RSPO3_HUMAN Increases Expression [28]
Histone deacetylase 8 (HDAC8) OT5L4RYX HDAC8_HUMAN Increases Expression [28]
Dedicator of cytokinesis protein 9 (DOCK9) OT84H8AD DOCK9_HUMAN Increases Expression [28]
Iroquois-class homeodomain protein IRX-2 (IRX2) OTBHXXQ2 IRX2_HUMAN Increases Expression [28]
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 (NMNAT2) OT5JLP2H NMNA2_HUMAN Increases Expression [28]
Thiamine transporter 2 (SLC19A3) OTOWP1CT S19A3_HUMAN Increases Expression [28]
E3 ubiquitin-protein ligase TRIM9 (TRIM9) OTKYG33W TRIM9_HUMAN Increases Expression [28]
Tripartite motif-containing protein 6 (TRIM6) OTBSMX0B TRIM6_HUMAN Increases Expression [28]
Protein TANC1 (TANC1) OTF6TZ8E TANC1_HUMAN Increases Expression [28]
Ethanolaminephosphotransferase 1 (SELENOI) OTX2A47A EPT1_HUMAN Increases Expression [28]
SRC kinase signaling inhibitor 1 (SRCIN1) OTQZNQQ5 SRCN1_HUMAN Decreases Expression [28]
Metal cation symporter ZIP8 (SLC39A8) OT6C6MNV S39A8_HUMAN Increases Expression [28]
Immortalization up-regulated protein (C19ORF33) OTOYH74A IMUP_HUMAN Increases Expression [28]
PR domain zinc finger protein 14 (PRDM14) OTWZKY4L PRD14_HUMAN Increases Expression [28]
NUAK family SNF1-like kinase 2 (NUAK2) OTUEZLO8 NUAK2_HUMAN Decreases Expression [28]
CYFIP-related Rac1 interactor A (CYRIA) OT2VJ767 CYRIA_HUMAN Increases Expression [28]
Ras-related protein Rab-17 (RAB17) OT7NBUGQ RAB17_HUMAN Increases Expression [28]
B-cell lymphoma/leukemia 11A (BCL11A) OTI6ZBP6 BC11A_HUMAN Increases Expression [28]
Kinesin-like protein KIF13A (KIF13A) OTSSZGBQ KI13A_HUMAN Decreases Expression [28]
Sphingosine 1-phosphate receptor 5 (S1PR5) OTQF1R0U S1PR5_HUMAN Increases Expression [28]
Synaptotagmin-4 (SYT4) OTA1D7VL SYT4_HUMAN Increases Expression [28]
Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1) OT38HXJP CRLD1_HUMAN Increases Expression [28]
Sorting nexin-25 (SNX25) OT8JY8M1 SNX25_HUMAN Decreases Expression [28]
Leucine-rich repeat neuronal protein 3 (LRRN3) OT7X0AA7 LRRN3_HUMAN Increases Expression [28]
Calsyntenin-2 (CLSTN2) OT2PJYHX CSTN2_HUMAN Increases Expression [28]
SPARC-related modular calcium-binding protein 1 (SMOC1) OTJG2JQY SMOC1_HUMAN Decreases Expression [28]
DNA transposase THAP9 (THAP9) OTY4TSJO THAP9_HUMAN Decreases Expression [28]
SLIT and NTRK-like protein 6 (SLITRK6) OTLNWI5G SLIK6_HUMAN Increases Expression [28]
Epithelial splicing regulatory protein 2 (ESRP2) OTVTKJ4I ESRP2_HUMAN Increases Expression [28]
Dedicator of cytokinesis protein 5 (DOCK5) OT63I0CL DOCK5_HUMAN Increases Expression [28]
NIPA-like protein 2 (NIPAL2) OTX9UREP NPAL2_HUMAN Increases Expression [28]
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial (MTHFD2L) OTDYNXRG MTD2L_HUMAN Increases Expression [28]
Nuclear body protein SP140-like protein (SP140L) OTL30JKT SP14L_HUMAN Increases Expression [28]
Chondrolectin (CHODL) OTVCNOUQ CHODL_HUMAN Increases Expression [28]
Homeobox protein NANOG (NANOG) OTUEY1FM NANOG_HUMAN Increases Expression [28]
Adhesion G protein-coupled receptor L3 (ADGRL3) OT81Q8LY AGRL3_HUMAN Decreases Expression [28]
Netrin-4 (NTN4) OTDRRMP3 NET4_HUMAN Decreases Expression [28]
V-type proton ATPase 116 kDa subunit a 4 (ATP6V0A4) OT149Z7Q VPP4_HUMAN Increases Expression [28]
Collectrin (CLTRN) OTXGFJ3F CLTRN_HUMAN Decreases Expression [28]
Ethanolamine kinase 1 (ETNK1) OTDKB4DQ EKI1_HUMAN Increases Expression [28]
Popeye domain-containing protein 3 (POPDC3) OTN4FJ5J POPD3_HUMAN Decreases Expression [28]
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) OTAQD3YV ARNT2_HUMAN Decreases Expression [28]
Prokineticin-2 (PROK2) OT70IFEZ PROK2_HUMAN Decreases Expression [28]
Sodium/potassium/calcium exchanger 3 (SLC24A3) OTEJN38N NCKX3_HUMAN Increases Expression [28]
Mineralization regulator ANKH (ANKH) OTCN25R5 ANKH_HUMAN Increases Expression [28]
UPF0606 protein KIAA1549 (KIAA1549) OTA5B18F K1549_HUMAN Decreases Expression [28]
Band 4.1-like protein 5 (EPB41L5) OTPPQPLU E41L5_HUMAN Increases Expression [28]
Solute carrier family 40 member 1 (SLC40A1) OT8RV2VY S40A1_HUMAN Increases Expression [28]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) OT5V52LN TNR12_HUMAN Increases Expression [28]
Mid1-interacting protein 1 (MID1IP1) OTFCORJM M1IP1_HUMAN Increases Expression [28]
Frizzled-3 (FZD3) OTIWDN78 FZD3_HUMAN Decreases Expression [28]
Nuclear receptor-interacting protein 3 (NRIP3) OTU15GMK NRIP3_HUMAN Decreases Expression [28]
Signal peptide, CUB and EGF-like domain-containing protein 2 (SCUBE2) OT661S7D SCUB2_HUMAN Decreases Expression [28]
Solute carrier family 52, riboflavin transporter, member 3 (SLC52A3) OT1FHFMK S52A3_HUMAN Increases Expression [28]
E3 ubiquitin-protein ligase Jade-2 (JADE2) OTVG2MYF JADE2_HUMAN Increases Expression [28]
Ras-related GTP-binding protein D (RRAGD) OTXLVWAH RRAGD_HUMAN Decreases Expression [28]
Coiled-coil domain-containing protein 177 (CCDC177) OT44WWP5 CC177_HUMAN Decreases Expression [28]
Sialic acid synthase (NANS) OTMQ2FUH SIAS_HUMAN Increases Expression [28]
Platelet-derived growth factor C (PDGFC) OT3ZJ0XU PDGFC_HUMAN Increases Expression [28]
N-lysine methyltransferase SMYD2 (SMYD2) OTN8035R SMYD2_HUMAN Increases Expression [28]
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A) OTWHOVZS BAZ1A_HUMAN Increases Expression [28]
Olfactomedin-like protein 3 (OLFML3) OTDN45FN OLFL3_HUMAN Increases Expression [28]
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (C1GALT1) OT2ZSZ6P C1GLT_HUMAN Increases Expression [28]
Glutaredoxin-2, mitochondrial (GLRX2) OT4LIRBC GLRX2_HUMAN Increases Expression [28]
Protein reprimo (RPRM) OTNNBAS1 RPRM_HUMAN Increases Expression [28]
Probable G-protein coupled receptor 173 (GPR173) OT8F8XR1 GP173_HUMAN Decreases Expression [28]
Probable G-protein coupled receptor 27 (GPR27) OTH4KQPI GPR27_HUMAN Decreases Expression [28]
Asc-type amino acid transporter 1 (SLC7A10) OTN1S03Q AAA1_HUMAN Increases Expression [28]
EMILIN-3 (EMILIN3) OT2BZTSU EMIL3_HUMAN Decreases Expression [28]
Teneurin-2 (TENM2) OTPLUYEF TEN2_HUMAN Increases Expression [28]
Obg-like ATPase 1 (OLA1) OTAPOTTG OLA1_HUMAN Decreases Expression [28]
Muscleblind-like protein 3 (MBNL3) OT2T2YOK MBNL3_HUMAN Increases Expression [28]
RNA binding protein fox-1 homolog 1 (RBFOX1) OTFPKEL7 RFOX1_HUMAN Increases Expression [28]
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB) OTXLLSIZ MCUB_HUMAN Decreases Expression [28]
Ras-related protein Rab-20 (RAB20) OTP9OOVS RAB20_HUMAN Increases Expression [28]
Very long chain fatty acid elongase 2 (ELOVL2) OTDAF6U3 ELOV2_HUMAN Decreases Expression [28]
Sphingosine kinase 1 (SPHK1) OTWYPBVD SPHK1_HUMAN Increases Expression [28]
Dapper homolog 1 (DACT1) OT19Z704 DACT1_HUMAN Increases Expression [28]
Endoplasmic reticulum aminopeptidase 1 (ERAP1) OT72S99B ERAP1_HUMAN Decreases Expression [28]
Transcription factor CP2-like protein 1 (TFCP2L1) OT7QIJ0X TF2L1_HUMAN Increases Expression [28]
Myoferlin (MYOF) OTRFC3IJ MYOF_HUMAN Increases Expression [28]
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) OTW3T4B2 IRPL1_HUMAN Decreases Expression [28]
Tropomodulin-2 (TMOD2) OTTTUH2W TMOD2_HUMAN Increases Expression [28]
Potassium voltage-gated channel subfamily D member 2 (KCND2) OTIFUVV7 KCND2_HUMAN Decreases Expression [28]
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22) OT452ZDC ADA22_HUMAN Decreases Expression [28]
DOMON domain-containing protein FRRS1L (FRRS1L) OT24ABVC FRS1L_HUMAN Decreases Expression [28]
Peroxisomal sarcosine oxidase (PIPOX) OTWTCOTN SOX_HUMAN Increases Expression [28]
MyoD family inhibitor domain-containing protein (MDFIC) OTSRYBWZ MDFIC_HUMAN Increases Expression [28]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1) OTJISZOX PLCE1_HUMAN Increases Expression [28]
Junctional cadherin 5-associated protein (JCAD) OT7G1WJW JCAD_HUMAN Increases Expression [28]
Protocadherin-10 (PCDH10) OT2GIT0E PCD10_HUMAN Increases Expression [28]
Kelch-like protein 14 (KLHL14) OTYOS55H KLH14_HUMAN Increases Expression [28]
Short transient receptor potential channel 4 (TRPC4) OTYY9DPV TRPC4_HUMAN Decreases Expression [28]
Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) OTU4J3ZI HEY2_HUMAN Increases Expression [28]
Homeobox expressed in ES cells 1 (HESX1) OT5E2Z4G HESX1_HUMAN Decreases Expression [28]
Small conductance calcium-activated potassium channel protein 3 (KCNN3) OT11KYA8 KCNN3_HUMAN Decreases Expression [28]
Testin (TES) OTL8PP6V TES_HUMAN Increases Expression [28]
Sushi domain-containing protein 2 (SUSD2) OTSJTAZP SUSD2_HUMAN Increases Expression [28]
Transcription factor COE1 (EBF1) OTZ61YYH COE1_HUMAN Increases Expression [28]
Zinc finger transcription factor Trps1 (TRPS1) OT7XPPEL TRPS1_HUMAN Increases Expression [28]
Scm-like with four MBT domains protein 1 (SFMBT1) OTKMZIBW SMBT1_HUMAN Decreases Expression [28]
Krueppel-like factor 15 (KLF15) OTGMQMVR KLF15_HUMAN Increases Expression [28]
E3 ISG15--protein ligase HERC5 (HERC5) OTZ5PR39 HERC5_HUMAN Increases Expression [28]
Potassium voltage-gated channel subfamily G member 1 (KCNG1) OTZ9ZRG8 KCNG1_HUMAN Increases Expression [28]
Forkhead box protein D3 (FOXD3) OTXYV6GO FOXD3_HUMAN Increases Expression [28]
Purine-rich element-binding protein gamma (PURG) OTXPQDWN PURG_HUMAN Decreases Expression [28]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (GNG8) OT9YHSF1 GBG8_HUMAN Decreases Expression [28]
F-box only protein 2 (FBXO2) OTF3677S FBX2_HUMAN Increases Expression [28]
Ribosomal protein S6 kinase alpha-6 (RPS6KA6) OTTY0FI2 KS6A6_HUMAN Decreases Expression [28]
Nocturnin (NOCT) OTVSYP2D NOCT_HUMAN Increases Expression [28]
Adherens junction-associated protein 1 (AJAP1) OTAAW121 AJAP1_HUMAN Increases Expression [28]
TRAF2 and NCK-interacting protein kinase (TNIK) OTDZBJ4K TNIK_HUMAN Increases Expression [28]
Cdc42 effector protein 3 (CDC42EP3) OTUZ3U9Z BORG2_HUMAN Decreases Expression [28]
Disintegrin and metalloproteinase domain-containing protein 28 (ADAM28) OT3GBVHL ADA28_HUMAN Increases Expression [28]
ETS-related transcription factor Elf-5 (ELF5) OTLRU8YF ELF5_HUMAN Increases Expression [28]
Procollagen C-endopeptidase enhancer 2 (PCOLCE2) OTSUEQZ1 PCOC2_HUMAN Increases Expression [28]
DENN domain-containing protein 2A (DENND2A) OT01E1PL DEN2A_HUMAN Decreases Expression [28]
NACHT and WD repeat domain-containing protein 2 (NWD2) OTN47UBK NWD2_HUMAN Increases Expression [28]
Protein HEG homolog 1 (HEG1) OT3CUXA7 HEG1_HUMAN Decreases Expression [28]
Neurabin-1 (PPP1R9A) OTJL2TOC NEB1_HUMAN Decreases Expression [28]
RING finger protein 150 (RNF150) OTAMSBK5 RN150_HUMAN Increases Expression [28]
E3 ubiquitin-protein ligase CBL-C (CBLC) OT3RKZI9 CBLC_HUMAN Increases Expression [28]
Frizzled-10 (FZD10) OTSAENLT FZD10_HUMAN Increases Expression [28]
Apoptosis-associated speck-like protein containing a CARD (PYCARD) OT67RON3 ASC_HUMAN Increases Expression [28]
Sex comb on midleg-like protein 1 (SCML1) OT7V5DAR SCML1_HUMAN Increases Expression [28]
DNA polymerase iota (POLI) OTBA4DCE POLI_HUMAN Decreases Expression [28]
LIM and calponin homology domains-containing protein 1 (LIMCH1) OTYPC4XA LIMC1_HUMAN Decreases Expression [28]
Cystine/glutamate transporter (SLC7A11) OTKJ6PXW XCT_HUMAN Increases Expression [28]
Catenin delta-2 (CTNND2) OTYKE30Y CTND2_HUMAN Decreases Expression [28]
Tenascin-N (TNN) OTQK2AMX TENN_HUMAN Increases Expression [28]
Short transient receptor potential channel 6 (TRPC6) OT5J7HVM TRPC6_HUMAN Increases Expression [28]
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 (FUT9) OTLIJBQY FUT9_HUMAN Decreases Expression [28]
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A) OT74EK7Z PDE10_HUMAN Decreases Expression [28]
Leucine zipper putative tumor suppressor 1 (LZTS1) OTXXL864 LZTS1_HUMAN Increases Expression [28]
C-C motif chemokine 26 (CCL26) OT2B7HR9 CCL26_HUMAN Increases Expression [28]
TBC1 domain family member 30 (TBC1D30) OTG8HGSI TBC30_HUMAN Decreases Expression [28]
Band 4.1-like protein 3 (EPB41L3) OTS6CHG2 E41L3_HUMAN Increases Expression [28]
Axin-2 (AXIN2) OTRMGQNU AXIN2_HUMAN Increases Expression [28]
Retinal homeobox protein Rx (RAX) OTJ3YCE7 RX_HUMAN Decreases Expression [28]
Tudor and KH domain-containing protein (TDRKH) OTV21BN1 TDRKH_HUMAN Decreases Expression [28]
Transmembrane emp24 domain-containing protein 5 (TMED5) OT70W1J8 TMED5_HUMAN Increases Expression [28]
C2 domain-containing protein 2 (C2CD2) OTL1K0OB C2CD2_HUMAN Decreases Expression [28]
Sal-like protein 2 (SALL2) OTQWI68Q SALL2_HUMAN Decreases Expression [28]
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) OTJBDX0Y VPP2_HUMAN Decreases Expression [28]
Beta/gamma crystallin domain-containing protein 1 (CRYBG1) OTIPDI15 CRBG1_HUMAN Increases Expression [28]
Transcription factor HES-2 (HES2) OTMWY2KV HES2_HUMAN Increases Expression [28]
Intraflagellar transport protein 25 homolog (IFT25) OTDR1HG6 IFT25_HUMAN Decreases Expression [28]
Low-density lipoprotein receptor-related protein 12 (LRP12) OTRT1UJ7 LRP12_HUMAN Decreases Expression [28]
Protein mab-21-like 2 (MAB21L2) OTZM5VMX MB212_HUMAN Decreases Expression [28]
Protocadherin beta-14 (PCDHB14) OTFZF1ST PCDBE_HUMAN Decreases Expression [28]
Transcription factor MafB (MAFB) OTH2N3T8 MAFB_HUMAN Increases Expression [28]
Neuropeptide FF receptor 2 (NPFFR2) OTVI4Q85 NPFF2_HUMAN Increases Expression [28]
Beta-secretase 2 (BACE2) OTO5YQVK BACE2_HUMAN Increases Expression [28]
Glypican-6 (GPC6) OTNJBESF GPC6_HUMAN Decreases Expression [28]
Adhesion G-protein coupled receptor G1 (ADGRG1) OTQBB8NT AGRG1_HUMAN Decreases Expression [28]
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1) OTK53GUD HS3SB_HUMAN Decreases Expression [28]
LHFPL tetraspan subfamily member 6 protein (LHFPL6) OTY6LHJY LHPL6_HUMAN Increases Expression [28]
Mitochondrial inner membrane protease ATP23 homolog (ATP23) OT303R2T ATP23_HUMAN Increases Expression [28]
Gap junction alpha-3 protein (GJA3) OTXV6ETF CXA3_HUMAN Increases Expression [28]
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) OTTLD0KB SQOR_HUMAN Increases Expression [28]
Cadherin-10 (CDH10) OTK3D5WP CAD10_HUMAN Increases Expression [28]
Calpain-6 (CAPN6) OT8K5PR5 CAN6_HUMAN Decreases Expression [28]
AP-1 complex subunit mu-2 (AP1M2) OTUE5YLC AP1M2_HUMAN Increases Expression [28]
Dual specificity protein phosphatase 10 (DUSP10) OTNG467B DUS10_HUMAN Increases Expression [28]
Collagen alpha-1(XI) chain (COL11A1) OTB0DRMS COBA1_HUMAN Increases Expression [35]
Neuronal growth regulator 1 (NEGR1) OT57ECW9 NEGR1_HUMAN Increases Expression [35]
Bone morphogenetic protein receptor type-1B (BMPR1B) OTGFN0OD BMR1B_HUMAN Affects Expression [30]
Huntingtin-interacting protein 1 (HIP1) OT7AKCFQ HIP1_HUMAN Increases Expression [29]
Homeobox protein Meis2 (MEIS2) OTG4ADLM MEIS2_HUMAN Affects Expression [30]
T-box transcription factor TBX3 (TBX3) OTM64N7K TBX3_HUMAN Affects Expression [30]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [36]
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (ST8SIA3) OTG9MXV9 SIA8C_HUMAN Affects Expression [30]
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) OTX1C2GS DYRK3_HUMAN Increases Expression [29]
Transmembrane and coiled-coil domains protein 2 (TMCC2) OT0D7IYD TMCC2_HUMAN Increases Expression [29]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G) OT8V1J4M GA45G_HUMAN Increases Expression [37]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Increases Acetylation [37]
Nuclear factor 1 C-type (NFIC) OTLMCUIB NFIC_HUMAN Affects Expression [30]
Myb-related protein A (MYBL1) OTBJMC2P MYBA_HUMAN Increases Expression [29]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Expression [38]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Increases Expression [37]
Interleukin-3 receptor subunit alpha (IL3RA) OTDC3Y8O IL3RA_HUMAN Increases Expression [29]
G-protein coupled receptor 183 (GPR183) OTRILX7G GP183_HUMAN Decreases Expression [29]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [39]
Signal transducer and activator of transcription 3 (STAT3) OTAAGKYZ STAT3_HUMAN Increases Acetylation [40]
OX-2 membrane glycoprotein (CD200) OTQEQSRT OX2G_HUMAN Affects Expression [30]
Tyrosine-protein phosphatase non-receptor type 9 (PTPN9) OTNAR1I2 PTN9_HUMAN Affects Expression [30]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Increases Expression [39]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Decreases Expression [36]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Increases Acetylation [41]
Guanylate cyclase soluble subunit alpha-1 (GUCY1A1) OTPTCBUN GCYA1_HUMAN Affects Expression [30]
Unconventional myosin-Ie (MYO1E) OTM9YSIZ MYO1E_HUMAN Increases Expression [29]
Cyclin-dependent kinase 5 activator 1 (CDK5R1) OTJELWK0 CD5R1_HUMAN Decreases Expression [29]
Histone H3.1t (H3-4) OTY6ITYF H31T_HUMAN Increases Acetylation [41]
Rho GTPase-activating protein 31 (ARHGAP31) OTUYTF4I RHG31_HUMAN Affects Expression [30]
Fidgetin (FIGN) OTJF6EZR FIGN_HUMAN Affects Expression [30]
NHS-like protein 2 (NHSL2) OT8U1P8E NHSL2_HUMAN Affects Expression [30]
Failed axon connections homolog (FAXC) OTU0RGB0 FAXC_HUMAN Affects Expression [30]
AT-rich interactive domain-containing protein 2 (ARID2) OTIRJXWM ARID2_HUMAN Affects Expression [30]
Male-specific lethal 1 homolog (MSL1) OTXLFYLB MSL1_HUMAN Decreases Expression [29]
Rab11 family-interacting protein 1 (RAB11FIP1) OT0T71OW RFIP1_HUMAN Increases Expression [29]
Protein lin-28 homolog B (LIN28B) OTVWP0FN LN28B_HUMAN Decreases Expression [30]
Leucine-rich repeat transmembrane neuronal protein 1 (LRRTM1) OTKI3IU9 LRRT1_HUMAN Affects Expression [30]
Transforming growth factor beta activator LRRC33 (NRROS) OT9WNOKY LRC33_HUMAN Decreases Expression [29]
tRNA-uridine aminocarboxypropyltransferase 1 (DTWD1) OT95QT6P DTWD1_HUMAN Decreases Expression [29]
TBC1 domain family member 16 (TBC1D16) OTPR3C6A TBC16_HUMAN Increases Expression [29]
Transforming growth factor-beta receptor-associated protein 1 (TGFBRAP1) OT80QNR5 TGFA1_HUMAN Affects Expression [30]
Alpha-2,8-sialyltransferase 8B (ST8SIA2) OTRBBBD8 SIA8B_HUMAN Affects Expression [30]
Protein FAN (NSMAF) OTYNVZ23 FAN_HUMAN Affects Expression [30]
Protein Jumonji (JARID2) OT14UM8H JARD2_HUMAN Increases Expression [29]
ELL-associated factor 2 (EAF2) OTSOET5L EAF2_HUMAN Increases Expression [29]
Abasic site processing protein HMCES (HMCES) OTVRDL6U HMCES_HUMAN Increases Expression [29]
Protein FAM163A (FAM163A) OT0MYZ0F F163A_HUMAN Affects Expression [30]
Bcl-2-modifying factor (BMF) OT90NSLI BMF_HUMAN Increases Expression [29]
Small integral membrane protein 14 (SMIM14) OT47IF19 SIM14_HUMAN Increases Expression [29]
Sialidase-1 (NEU1) OTH9BY8Y NEUR1_HUMAN Increases Expression [29]
Partner of Y14 and mago (PYM1) OTEZ2WUO PYM1_HUMAN Decreases Expression [29]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1) OTM3B3OA TBL1R_HUMAN Affects Expression [30]
E3 ubiquitin-protein ligase TRIM8 (TRIM8) OTS6JFR0 TRIM8_HUMAN Affects Expression [30]
Sentrin-specific protease 6 (SENP6) OT05LLF4 SENP6_HUMAN Affects Expression [30]
Tumor protein 63 (TP63) OT0WOOKQ P63_HUMAN Increases Expression [42]
Popeye domain-containing protein 2 (POPDC2) OTDAZSY5 POPD2_HUMAN Affects Expression [30]
F-box only protein 8 (FBXO8) OTZNGJGW FBX8_HUMAN Affects Expression [30]
Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) OTTVT4MB TNR19_HUMAN Increases Expression [29]
AP-5 complex subunit sigma-1 (AP5S1) OTGS53SC AP5S1_HUMAN Decreases Expression [29]
Pre-mRNA-splicing factor RBM22 (RBM22) OTFW0IGK RBM22_HUMAN Decreases Expression [29]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1) OTY6ZHVA RGL1_HUMAN Increases Expression [29]
Programmed cell death 1 ligand 1 (CD274) OTJ0VFDL PD1L1_HUMAN Increases Expression [40]
Coiled-coil and C2 domain-containing protein 2A (CC2D2A) OTFGRGFR C2D2A_HUMAN Affects Expression [30]
Histone deacetylase 9 (HDAC9) OTO8O0LF HDAC9_HUMAN Decreases Expression [36]
Lactosylceramide alpha-2,3-sialyltransferase (ST3GAL5) OT27CCUF SIAT9_HUMAN Increases Expression [29]
RING finger protein 24 (RNF24) OTUZI597 RNF24_HUMAN Increases Expression [29]
Phosphatidylinositide phosphatase SAC2 (INPP5F) OTPKUY50 SAC2_HUMAN Increases Expression [29]
DmX-like protein 1 (DMXL1) OTWVL31L DMXL1_HUMAN Increases Expression [29]
Cystathionine beta-synthase (CBS) OT46FSKD CBS_HUMAN Increases ADR [43]
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) OT53SIZG NAA15_HUMAN Increases ADR [43]
Methylenetetrahydrofolate reductase (MTHFR) OTUBJSR7 MTHR_HUMAN Increases ADR [43]
------------------------------------------------------------------------------------
⏷ Show the Full List of 1019 DOT(s)

Test Results of This Drug Combination in Other Disease Systems

Indication DrugCom ID Cell Line Status REF
Breast Cancer DCBG7QK N. A. Phase 1 [1]
------------------------------------------------------------------------------------

References

1 ClinicalTrials.gov (NCT00632489) LBH589 in Combination With Capecitabine Plus/Minus () Lapatinib in Breast Cancer Patients
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5692).
3 Lapatinib FDA Label
4 Panobinostat FDA Label
5 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
6 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7489).
7 UGT-dependent regioselective glucuronidation of ursodeoxycholic acid and obeticholic acid and selective transport of the consequent acyl glucuronides by OATP1B1 and 1B3. Chem Biol Interact. 2019 Sep 1;310:108745. doi: 10.1016/j.cbi.2019.108745. Epub 2019 Jul 9.
8 Triple negative breast cancer--current status and prospective targeted treatment based on HER1 (EGFR), TOP2A and C-MYC gene assessment. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2009 Mar;153(1):13-7.
9 Inhibition of eEF-2 kinase sensitizes human nasopharyngeal carcinoma cells to lapatinib-induced apoptosis through the Src and Erk pathways.BMC Cancer. 2016 Oct 19;16(1):813.
10 Tarascon Pocket Pharmacopoeia 2018 Classic Shirt-Pocket Edition.
11 The role of efflux and uptake transporters in [N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, lapatinib) disposition and drug interactions. Drug Metab Dispos. 2008 Apr;36(4):695-701.
12 Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib. Mol Pharmacol. 2010 Oct;78(4):693-703.
13 Clinical pharmacokinetics of tyrosine kinase inhibitors. Cancer Treat Rev. 2009 Dec;35(8):692-706.
14 The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer. Cancer Res. 2005 Jan 1;65(1):18-25.
15 Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicol Sci. 2010 Dec; 118(2):485-500.
16 P450 3A-catalyzed O-dealkylation of lapatinib induces mitochondrial stress and activates Nrf2. Chem Res Toxicol. 2016 May 16;29(5):784-96.
17 Combining lapatinib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressing breast cancer cells. Oncogene. 2005 Sep 15;24(41):6213-21. doi: 10.1038/sj.onc.1208774.
18 CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models. Genes Cancer. 2014 Jul;5(7-8):261-72. doi: 10.18632/genesandcancer.24.
19 Effects of lapatinib on cell proliferation and apoptosis in NB4 cells. Oncol Lett. 2018 Jan;15(1):235-242. doi: 10.3892/ol.2017.7342. Epub 2017 Nov 3.
20 The involvement of hepatic cytochrome P450s in the cytotoxicity of lapatinib. Toxicol Sci. 2023 Dec 21;197(1):69-78. doi: 10.1093/toxsci/kfad099.
21 Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. Chem Res Toxicol. 2017 May 15;30(5):1219-1229. doi: 10.1021/acs.chemrestox.7b00048. Epub 2017 May 4.
22 Suppression of HER2/HER3-mediated growth of breast cancer cells with combinations of GDC-0941 PI3K inhibitor, trastuzumab, and pertuzumab. Clin Cancer Res. 2009 Jun 15;15(12):4147-56. doi: 10.1158/1078-0432.CCR-08-2814. Epub 2009 Jun 9.
23 Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes. Toxicol Lett. 2018 Jul;291:138-148. doi: 10.1016/j.toxlet.2018.04.010. Epub 2018 Apr 12.
24 Association of CYP1A1 and CYP1B1 inhibition in in vitro assays with drug-induced liver injury. J Toxicol Sci. 2021;46(4):167-176. doi: 10.2131/jts.46.167.
25 The K-Ras effector p38 MAPK confers intrinsic resistance to tyrosine kinase inhibitors by stimulating EGFR transcription and EGFR dephosphorylation. J Biol Chem. 2017 Sep 8;292(36):15070-15079. doi: 10.1074/jbc.M117.779488. Epub 2017 Jul 24.
26 HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer. J Clin Oncol. 2011 Feb 20;29(6):667-73. doi: 10.1200/JCO.2010.31.3197. Epub 2011 Jan 18.
27 Niclosamide inhibits epithelial-mesenchymal transition and tumor growth in lapatinib-resistant human epidermal growth factor receptor 2-positive breast cancer. Int J Biochem Cell Biol. 2016 Feb;71:12-23. doi: 10.1016/j.biocel.2015.11.014. Epub 2015 Nov 28.
28 A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.
29 Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells. Arch Toxicol. 2021 May;95(5):1631-1645. doi: 10.1007/s00204-021-03014-2. Epub 2021 Mar 26.
30 The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects. Clin Cancer Res. 2016 May 15;22(10):2534-44. doi: 10.1158/1078-0432.CCR-15-1666. Epub 2016 Jan 5.
31 Protein methyltransferases as a target class for drug discovery. Nat Rev Drug Discov. 2009 Sep;8(9):724-32.
32 Panobinostat for the treatment of multiple myeloma: the evidence to date. J Blood Med. 2015 Oct 8;6:269-76.
33 Panobinostat for the treatment of relapsed or relapsed/refractory multiple myeloma: pharmacology and clinical outcomes. Expert Rev Clin Pharmacol. 2016;9(1):35-48.
34 Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells. Mol Cancer Ther. 2014 May;13(5):1142-54.
35 Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests. Arch Toxicol. 2017 Feb;91(2):839-864.
36 Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis. PLoS One. 2018 Nov 27;13(11):e0207915. doi: 10.1371/journal.pone.0207915. eCollection 2018.
37 SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-B/STAT3 complex to its promoter in malignant lymphoid cells. Cell Death Dis. 2013 May 16;4(5):e635. doi: 10.1038/cddis.2013.159.
38 Resveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathway. Mol Pharmacol. 2012 Dec;82(6):1030-41. doi: 10.1124/mol.112.079624. Epub 2012 Aug 24.
39 Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. Neuro Oncol. 2008 Jun;10(3):309-19. doi: 10.1215/15228517-2007-063. Epub 2008 Apr 29.
40 Essential role of HDAC6 in the regulation of PD-L1 in?melanoma. Mol Oncol. 2016 May;10(5):735-750. doi: 10.1016/j.molonc.2015.12.012. Epub 2016 Jan 6.
41 A systematic assessment of radiation dose enhancement by 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2009 Mar 1;73(3):904-12. doi: 10.1016/j.ijrobp.2008.10.032.
42 Induction of TAp63 by histone deacetylase inhibitors. Biochem Biophys Res Commun. 2010 Jan 22;391(4):1748-51. doi: 10.1016/j.bbrc.2009.12.147. Epub 2009 Dec 30.
43 ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.