Details of the Drug Combinations

General Information of This Drug (ID: DM3Q1SM)

Drug Name

obeticholic acid DM3Q1SM

Synonyms

INT747; INT-747; 6-ethylchenodeoxycholic acid; 6-ECDCA; OCA; 6-Et CDCA

Indication

Disease Entry	ICD 11	Status	REF
Primary biliary cholangitis	DB96.1	Approved	[1]
Insomnia	7A00-7A0Z	Clinical trial	[2]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

5 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Obeticholic acid + Ursodeoxycholic acid	DCDR1RC	Ursodeoxycholic acid	PBC	[3]
Obeticholic acid + Obeticholic acid	DC5CI57	Obeticholic acid	Biliary Atresia	[4]
Obeticholic acid + Atorvastatin	DC1ZVYZ	Atorvastatin	Nonalcoholic Steatohepatitis	[5]
Obeticholic acid + Bezafibrate	DCZF5OG	Bezafibrate	Primary Biliary Cholangitis	[6]
Obeticholic acid + Ursodeoxycholic acid	DCWET3R	Ursodeoxycholic acid	Primary Biliary Cirrhosis	[7]
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References

1	2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76.
2	Nuclear receptors and lipid physiology: opening the X-files. Science. 2001 Nov 30;294(5548):1866-70.
3	ClinicalTrials.gov (NCT04076527) Prospective, Multicenter Cohort Study on Primary Biliary Cholangitis
4	ClinicalTrials.gov (NCT05321524) Obeticholic Acid in Pediatric Subjects With Biliary Atresia
5	ClinicalTrials.gov (NCT02633956) Combination Obeticholic Acid (OCA) and Statins for Monitoring of Lipids (CONTROL)
6	ClinicalTrials.gov (NCT05239468) Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC
7	ClinicalTrials.gov (NCT04956328) Study of Obeticholic AcidOCA?Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primay Biliary Cirrhosis (PBC)