Details of the Drug Combinations

General Information of This Drug (ID: DMKZJ7T)

Drug Name

GINKGOLIDE A DMKZJ7T

Synonyms

Ginkgolide A; 15291-75-5; CHEBI:5355; SCHEMBL340234; GTPL1861; LMPR0104540001; AB2000432; C07601

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

66 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
10-hydroxycamptothecin + GINKGOLIDE A	DCAYIQX	10-hydroxycamptothecin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Acetohydroxamic Acid + GINKGOLIDE A	DCC3S7L	Acetohydroxamic Acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Aliskiren + GINKGOLIDE A	DC6KXW6	Aliskiren	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Amantadine + GINKGOLIDE A	DCVRNMW	Amantadine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Anamorelin + GINKGOLIDE A	DCY8HFX	Anamorelin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Aprepitant + GINKGOLIDE A	DCXTX8N	Aprepitant	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Armodafinil + GINKGOLIDE A	DCMVRRN	Armodafinil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Asenapine + GINKGOLIDE A	DCF55PO	Asenapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Bepridil + GINKGOLIDE A	DC7CQDZ	Bepridil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
BIO-300 + GINKGOLIDE A	DCM3OTE	BIO-300	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Brincidofovir + GINKGOLIDE A	DCT4LYY	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cerivastatin + GINKGOLIDE A	DC0SL9F	Cerivastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clindamycin + GINKGOLIDE A	DCRZKKS	Clindamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cytarabine + GINKGOLIDE A	DCEHVVR	Cytarabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Diphenidol + GINKGOLIDE A	DCO8AM8	Diphenidol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Ruxolitinib	DCA2L25	Ruxolitinib	Hodgkin lymphoma (Cell Line: L-1236)	[2]
GINKGOLIDE A + Methotrexate	DC1GR7Y	Methotrexate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Triapine	DCN2VOB	Triapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Dexmedetomidine	DC85VBP	Dexmedetomidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Metyrosine	DC4UBHH	Metyrosine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Guanfacine	DCW6K1T	Guanfacine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Itraconazole	DCBELAY	Itraconazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Chlorzoxazone	DCZY22I	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Docetaxel	DCPCO8W	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Phenprocoumon	DC1HT2Z	Phenprocoumon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Pazopanib	DCULHXZ	Pazopanib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Armodafinil	DC6EK73	Armodafinil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Naringenin	DCY97FU	Naringenin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Arfolitixorin	DCUHT57	Arfolitixorin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Oseltamivir	DC4N9C2	Oseltamivir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Diazoxide	DC70HMM	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Allopurinol	DCXKUX1	Allopurinol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Idarubicin	DC4GJJE	Idarubicin	Glioblastoma? (Cell Line: T98G)	[2]
GINKGOLIDE A + Methocarbamol	DC22Y45	Methocarbamol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Abacavir	DC8BHGK	Abacavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Tropisetron	DCJ8JBN	Tropisetron	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Ethinyl estradiol	DC6J3TT	Ethinyl estradiol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Trimethobenzamide	DCRZXGW	Trimethobenzamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Mycophenolic acid	DCM8235	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Doxorubicin	DCR9G30	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Zileuton	DCM5347	Zileuton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Auranofin	DCYI6N4	Auranofin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + Cevimeline	DC2Z8RE	Cevimeline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + ML323	DCDBT59	ML323	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GINKGOLIDE A + AS-1949490	DCTYS2W	AS-1949490	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GSK2194069 + GINKGOLIDE A	DCMBL8D	GSK2194069	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Imatinib + GINKGOLIDE A	DCOZPH5	Imatinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Isoproterenol + GINKGOLIDE A	DCOZZPE	Isoproterenol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Leflunomide + GINKGOLIDE A	DCCKZ2N	Leflunomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Lubiprostone + GINKGOLIDE A	DCY19YP	Lubiprostone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Maprotiline + GINKGOLIDE A	DCWNIKE	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + GINKGOLIDE A	DC9Q88H	Mebutamate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mycophenolic acid + GINKGOLIDE A	DCNAK7U	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Naltrexone + GINKGOLIDE A	DCIWR0M	Naltrexone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pargyline + GINKGOLIDE A	DCH69RZ	Pargyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pentostatin + GINKGOLIDE A	DCSB1LS	Pentostatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
PMID28460551-Compound-2 + GINKGOLIDE A	DCFUBAR	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Primidone + GINKGOLIDE A	DCJ9A8M	Primidone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pyrazinamide + GINKGOLIDE A	DCZZTJG	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Ribavirin-TP + GINKGOLIDE A	DC1XBW8	Ribavirin-TP	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
SCH 727965 + GINKGOLIDE A	DC9TQUL	SCH 727965	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Sivelestat + GINKGOLIDE A	DCV0THM	Sivelestat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Tiagabine + GINKGOLIDE A	DCD6D1O	Tiagabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Trihexyphenidyl + GINKGOLIDE A	DCUKMZM	Trihexyphenidyl	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Vorinostat + GINKGOLIDE A	DCZ0UNT	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Zaleplon + GINKGOLIDE A	DC2OYYT	Zaleplon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
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⏷ Show the Full List of 66 DrugCom(s)

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1861).
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.