Details of the Drug Combinations

General Information of This Drug (ID: DMR6N7H)

Drug Name
Acetohexamide   DMR6N7H
Synonyms
Acetohexamid; Acetohexamida; Acetohexamidum; Dimelin; Dimelor; Dymelor; Gamadiabet; Hypoglicil; Metaglucina; Minoral; Ordimel; Tsiklamid; Acetohexamide Lilly Brand; Acetohexamide Salvat Brand; Lilly Brand of Acetohexamide; Ord imel; Salvat Brand of Acetohexamide; U 14812; A-178; Acetohexamida [INN-Spanish]; Acetohexamidum [INN-Latin]; Dimelin (antidiabetic); Dymelor (TN); U-14812; Acetohexamide (JP15/USP/INN); Acetohexamide [USAN:INN:BAN:JAN]; N-(p-Acetylbenzenesulfonyl)-N'-cyclohexylurea; N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea; 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea; 1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea; 1-(p-Acetylbenzenesulfonyl)-3-cyclohexylurea; 3-cyclohexyl-1-(p-acetylphenylsulfonyl)urea; 4-Acetyl-N-((cyclohexylamino)carbonyl)benzenesulfonamide; 4-Acetyl-N-[(cyclohexylamino)-carbonyl]benzenesulfonamide; 4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide; 4-acetyl-N-((cyclohexylamino)carbonyl)benzenesulf onamide
Indication
Disease Entry ICD 11 Status REF
Diabetic complication 5A2Y Approved [1]
Therapeutic Class
Hypoglycemic Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

52 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acarbose + Acetohexamide DC0DUAL Acarbose Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Mebutamate DCYD054 Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Picoplatin DC4YGSY Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Baclofen DCS04EG Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + PMID28460551-Compound-2 DCONFFH PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Mephenytoin DCORZOH Mephenytoin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Pamidronate DC4X8JS Pamidronate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Metyrosine DCIX73J Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Ciprofibrate DCMHI15 Ciprofibrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Arfolitixorin DCX4B8R Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Triflupromazine DCXF85G Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Eflornithine DCHSM83 Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Imatinib DCVS1FH Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Atenolol DCDX1RB Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Bortezomib DC7LH5O Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Methylene blue DC4K9KW Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Bumetanide DCZAMZJ Bumetanide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Hydralazine DCZFXTU Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Lacosamide DCQZIIO Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Vorinostat DCLF56W Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Atovaquone DCUQULP Atovaquone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohexamide + Cytarabine DCTEFZO Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aliskiren + Acetohexamide DCJV3WS Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Azatadine + Acetohexamide DCZBESG Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + Acetohexamide DCOX4QR BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Acetohexamide DC0LBCF Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cerivastatin + Acetohexamide DCM8WSI Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Citalopram + Acetohexamide DCOA7T4 Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Crotamiton + Acetohexamide DC1WMD1 Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Acetohexamide DCR2OGQ Desoxycorticosterone pivalate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dichlorphenamide + Acetohexamide DC51QY4 Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Docetaxel + Acetohexamide DCND4ZL Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Doxorubicin + Acetohexamide DCQ4T5C Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Acetohexamide DC3JF15 Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Entacapone + Acetohexamide DCTUK39 Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Epinephrine + Acetohexamide DCM472V Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Gefitinib + Acetohexamide DC0PSYH Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydroxychloroquine + Acetohexamide DCF44GH Hydroxychloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Idarubicin + Acetohexamide DCV0KD2 Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mefloquine + Acetohexamide DC0MOJV Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Memantine + Acetohexamide DCN3FZT Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Miglustat + Acetohexamide DCO73WU Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Acetohexamide DCZV52B Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pepstatin + Acetohexamide DCS11HV Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pinacidil + Acetohexamide DC9RC1O Pinacidil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Probenecid + Acetohexamide DCQJFCX Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pyrazinamide + Acetohexamide DC0S1VT Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Quinine + Acetohexamide DC5Y38F Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sitagliptin + Acetohexamide DCNR676 Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sumatriptan + Acetohexamide DCQXX7E Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tranexamic acid + Acetohexamide DC1EPRZ Tranexamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triflupromazine + Acetohexamide DCCBREM Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 52 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6793).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.