Details of the Drug Combinations

General Information of This Drug (ID: DMWT905)

Drug Name

Mefloquine DMWT905

Synonyms

Lariam; Mefloquin; Mefloquina; Mefloquinone; Mefloquinum; Mephloquine; Racemic mefloquine; Ro 215998; WR 142490; Lariam (Hydrochloride); Lariam (TN); Mefaquin (TN); Mefloquina [INN-Spanish]; Mefloquinum [INN-Latin]; RO 13-7224; RO 13-7225; Ro 21-5998; SPB-80406; WR-142490; Mefloquine (USAN/INN); Mefloquine [USAN:INN:BAN]; RTI1169-1-1; RTI1172-1-1; RTI1173-1-1; RTI1174-1-1; RTI1188-1-1; RTI1189-1-1; Ro 21-5998 (Hydrochloride); WR-142,490; WR-177,602; Ro-21-5998-001; Alpha-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol; Alpha-2-Piperidyl-2,8-bis(trifluoromethyl)quinoline-4-methanol; [2,8-bis(trifluoromethyl)quinolin-4-yl]-piperidin-2-ylmethanol; Erthro-.alpha.-[2-piperidyl]-2,8-bis[trifluoromethyl]-4-quinolinemethanol; (+)-(11R,2'S)-erythro-Mefloquine; (+)-Mefloquine; (+)-Threo-Mefloquine; (-)-(11S,2'R)-erythro-Mefloquine; (-)-Mefloquine; (-)-Threo-Mefloquine; (DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol; (R)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol; (R)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2S)-piperidin-2-yl]methanol; (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol; (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2S)-piperidin-2-yl]methanol; (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2R)-piperidin-2-yl]methanol

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Approved	[1]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[2]
Middle East Respiratory Syndrome (MERS)	1D64	Preclinical	[3]
Severe acute respiratory syndrome (SARS)	1D65	Preclinical	[3]
Progressive multifocal leukoencephalopathy	8A45.02	Investigative	[4]
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Therapeutic Class

Antimalarials

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

285 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Acamprosate + Mefloquine	DCK9UEK	Acamprosate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Acetazolamide + Mefloquine	DC01VCC	Acetazolamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Alfacalcidol + Mefloquine	DCBA29L	Alfacalcidol	DD2 (Cell Line: DD2)	[5]
Aliskiren + Mefloquine	DCZSCP5	Aliskiren	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Allopurinol + Mefloquine	DCYD7VL	Allopurinol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Amantadine + Mefloquine	DCU29G9	Amantadine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Aminosalicylic acid + Mefloquine	DCEZ81W	Aminosalicylic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Arfolitixorin + Mefloquine	DCXMA1O	Arfolitixorin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Armodafinil + Mefloquine	DCDAXT3	Armodafinil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Artemether + Mefloquine	DC7A9R2	Artemether	DD2 (Cell Line: DD2)	[5]
Artemether + Mefloquine	DCQXXBU	Artemether	Hepatoblastoma (Cell Line: HB3)	[5]
AS602868 + Mefloquine	DC7M053	AS602868	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Asenapine + Mefloquine	DCOJT4E	Asenapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Azelnidipine + Mefloquine	DC31ZOK	Azelnidipine	DD2 (Cell Line: DD2)	[5]
Azelnidipine + Mefloquine	DCHM2TI	Azelnidipine	Hepatoblastoma (Cell Line: HB3)	[5]
Bafilomycin A1 + Mefloquine	DCT1CR2	Bafilomycin A1	DD2 (Cell Line: DD2)	[5]
BGT226 + Mefloquine	DC8KOUU	BGT226	DD2 (Cell Line: DD2)	[5]
BHV-0223 + Mefloquine	DCHMUYW	BHV-0223	Hepatoblastoma (Cell Line: HB3)	[6]
Bifemelane + Mefloquine	DC175SE	Bifemelane	DD2 (Cell Line: DD2)	[5]
BIIB-021 + Mefloquine	DCNM7P1	BIIB-021	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Biperiden + Mefloquine	DCSYD64	Biperiden	DD2 (Cell Line: DD2)	[5]
BIX-01294 + Mefloquine	DCMEIA2	BIX-01294	DD2 (Cell Line: DD2)	[5]
BIX-01294 + Mefloquine	DCZ51Q1	BIX-01294	Hepatoblastoma (Cell Line: HB3)	[6]
Bortezomib + Mefloquine	DCOBNMX	Bortezomib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Brincidofovir + Mefloquine	DC435EZ	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Buspirone + Mefloquine	DCT77RM	Buspirone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Carfilzomib + Mefloquine	DCHCP60	Carfilzomib	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Carvedilol + Mefloquine	DCZH6RB	Carvedilol	DD2 (Cell Line: DD2)	[5]
Chlormezanone + Mefloquine	DC3PT5N	Chlormezanone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Chloroxine + Mefloquine	DCYMBL4	Chloroxine	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Chloroxine + Mefloquine	DCRFFQL	Chloroxine	Primitive neuroectodermal tumor (Cell Line: TC-32)	[5]
Chlorphenesin + Mefloquine	DCZMVK0	Chlorphenesin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Cilostazol + Mefloquine	DCXSYNS	Cilostazol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Citalopram + Mefloquine	DCW315W	Citalopram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Clindamycin + Mefloquine	DCEW26U	Clindamycin	DD2 (Cell Line: DD2)	[5]
Clopidogrel + Mefloquine	DCFZHZR	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Daidzin + Mefloquine	DCNUYEK	Daidzin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Daporinad + Mefloquine	DC6XEKJ	Daporinad	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Dasatinib + Mefloquine	DCKSUPG	Dasatinib	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Dasatinib + Mefloquine	DCXF0BX	Dasatinib	Primitive neuroectodermal tumor (Cell Line: TC-32)	[5]
Dihydroergotamine + Mefloquine	DCEATEO	Dihydroergotamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Dihydroergotamine + Mefloquine	DCV6JJQ	Dihydroergotamine	Hepatoblastoma (Cell Line: HB3)	[5]
Disopyramide + Mefloquine	DCWOT08	Disopyramide	DD2 (Cell Line: DD2)	[5]
Docetaxel + Mefloquine	DC2Q3BT	Docetaxel	DD2 (Cell Line: DD2)	[5]
Dopamine + Mefloquine	DCJF0IP	Dopamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Doxepin + Mefloquine	DCR9A55	Doxepin	DD2 (Cell Line: DD2)	[5]
Doxycycline + Mefloquine	DC60EYZ	Doxycycline	DD2 (Cell Line: DD2)	[5]
Enalaprilat + Mefloquine	DCOAEJN	Enalaprilat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Endoxifen + Mefloquine	DC0IJ6C	Endoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Entacapone + Mefloquine	DCT9PCF	Entacapone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Eptifibatide + Mefloquine	DCT2C9L	Eptifibatide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Estramustine + Mefloquine	DCXPN3V	Estramustine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Ethambutol + Mefloquine	DCK1HUQ	Ethambutol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Ethinyl estradiol + Mefloquine	DCNN96L	Ethinyl estradiol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Everolimus + Mefloquine	DCZVM37	Everolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Ezetimibe + Mefloquine	DCURNS1	Ezetimibe	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Fendiline + Mefloquine	DCX28PT	Fendiline	DD2 (Cell Line: DD2)	[5]
Flavonoid derivative 1 + Mefloquine	DCL3EWL	Flavonoid derivative 1	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Fosfomycin + Mefloquine	DCNBG49	Fosfomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
GDC-0084 + Mefloquine	DCOTCG3	GDC-0084	DD2 (Cell Line: DD2)	[5]
Gefitinib + Mefloquine	DCGA7HL	Gefitinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Ginsenoside Rb1 + Mefloquine	DC0WG15	Ginsenoside Rb1	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Gliclazide + Mefloquine	DCV9H84	Gliclazide	Hepatoblastoma (Cell Line: HB3)	[6]
GSK2126458 + Mefloquine	DCK0ZTL	GSK2126458	DD2 (Cell Line: DD2)	[5]
GSK618334 + Mefloquine	DCLZMZS	GSK618334	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Hydralazine + Mefloquine	DCLYWF4	Hydralazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Hyodeoxycholic acid + Mefloquine	DCNPRZP	Hyodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Imipramine + Mefloquine	DCCPUCJ	Imipramine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Isoproterenol + Mefloquine	DCD2MY6	Isoproterenol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Isosorbide dinitrate + Mefloquine	DCC3Q0F	Isosorbide dinitrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Ivermectin + Mefloquine	DCXF2SB	Ivermectin	DD2 (Cell Line: DD2)	[5]
K-134 + Mefloquine	DCXANUR	K-134	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
KN-62 + Mefloquine	DCGXNN9	KN-62	DD2 (Cell Line: DD2)	[5]
KN-62 + Mefloquine	DC5H4D3	KN-62	Hepatoblastoma (Cell Line: HB3)	[6]
L-165041 + Mefloquine	DC2ZP2R	L-165041	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Lacosamide + Mefloquine	DCW3BOR	Lacosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Lefaxin + Mefloquine	DC7EWLR	Lefaxin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Lidoflazine + Mefloquine	DC7RHOA	Lidoflazine	DD2 (Cell Line: DD2)	[5]
Lidoflazine + Mefloquine	DC89FCR	Lidoflazine	Hepatoblastoma (Cell Line: HB3)	[6]
Linagliptin + Mefloquine	DCD0J45	Linagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
MANOALIDE + Mefloquine	DCM5JM9	MANOALIDE	DD2 (Cell Line: DD2)	[5]
MANOALIDE + Mefloquine	DCR8TH7	MANOALIDE	Hepatoblastoma (Cell Line: HB3)	[6]
Maraviroc + Mefloquine	DC5GKNZ	Maraviroc	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mebendazole + Mefloquine	DCLDN5P	Mebendazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mebendazole + Mefloquine	DCW09SC	Mebendazole	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Mebendazole + Mefloquine	DCZ6NYQ	Mebendazole	Primitive neuroectodermal tumor (Cell Line: TC-32)	[5]
Mecamylamine + Mefloquine	DC0C4ZD	Mecamylamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Aprepitant	DCEAOY5	Aprepitant	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Meclofenamic acid	DCSYOET	Meclofenamic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Ribavirin-TP	DCF3TRT	Ribavirin-TP	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Sertraline	DCCA7DP	Sertraline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Mebutamate	DCTPBE6	Mebutamate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Triiodothyronine	DCR5DAQ	Triiodothyronine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Clindamycin	DCNW5EQ	Clindamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Diethylcarbamazine	DCGWMDC	Diethylcarbamazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + OZ277	DC3J9D5	OZ277	DD2 (Cell Line: DD2)	[5]
Mefloquine + OZ277	DC37Z5O	OZ277	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Lumefantrine	DC3O5Q3	Lumefantrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Lumefantrine	DCDRBXT	Lumefantrine	DD2 (Cell Line: DD2)	[5]
Mefloquine + Lumefantrine	DCANIUA	Lumefantrine	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Kanamycin	DC4KBHF	Kanamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Dactinomycin	DCPGY8I	Dactinomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Terazosin	DCUAW9Y	Terazosin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Tindamax	DCV795G	Tindamax	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Furazolidone	DCO80IV	Furazolidone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + GYKI-52466	DCL3H9K	GYKI-52466	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Artemether	DC6FDKN	Artemether	DD2 (Cell Line: DD2)	[5]
Mefloquine + Artemether	DCRPIPK	Artemether	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Trioxsalen	DC0BU5H	Trioxsalen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Repaglinide	DCOG1OK	Repaglinide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Vinblastine	DCMZVEX	Vinblastine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Anamorelin	DC0WCGZ	Anamorelin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Alvespimycin hydrochloride	DCD4RTL	Alvespimycin hydrochloride	DD2 (Cell Line: DD2)	[5]
Mefloquine + MK-3207	DCLEOI3	MK-3207	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Acitretin	DCJSQ00	Acitretin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Dexmedetomidine	DC92EKF	Dexmedetomidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Tranexamic acid	DCGVL4K	Tranexamic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + 10-hydroxycamptothecin	DC2FO6C	10-hydroxycamptothecin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Azelnidipine	DCKQBHT	Azelnidipine	DD2 (Cell Line: DD2)	[5]
Mefloquine + Azelnidipine	DCZV3W0	Azelnidipine	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Diltiazem	DCM99AW	Diltiazem	DD2 (Cell Line: DD2)	[5]
Mefloquine + Diltiazem	DC4BX3B	Diltiazem	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Pamidronate	DC4HWKK	Pamidronate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Palonosetron	DCUCK4T	Palonosetron	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Testosterone cypionate	DC86WP6	Testosterone cypionate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Guanfacine	DCSWHYJ	Guanfacine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Cinacalcet	DCW46P3	Cinacalcet	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Carglumic acid	DC60FAW	Carglumic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Chlorzoxazone	DCJQZ1I	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + ETHISTERONE	DCWTLTM	ETHISTERONE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Cilastatin	DC69FN6	Cilastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Galantamine	DCA9AOL	Galantamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + JZL195	DC918YN	JZL195	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Pazopanib	DC4C7KQ	Pazopanib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Phensuximide	DCE6YJW	Phensuximide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Fibrates	DCOZE6E	Fibrates	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + WAY-100635	DCX9LDU	WAY-100635	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Armodafinil	DCUY7F5	Armodafinil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Ciprofibrate	DC97GFD	Ciprofibrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Mifepristone	DC7JE6B	Mifepristone	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Mefloquine + Pentamidine	DCM3A5M	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + PFK-158	DCN10DO	PFK-158	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Sulfapyridine	DCTSQ20	Sulfapyridine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Niclosamide	DCB98HQ	Niclosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Eflornithine	DCO3RTB	Eflornithine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + PF-02545920	DCUG7BU	PF-02545920	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Norcisapride	DCI2KTB	Norcisapride	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Etonogestrel	DCWITE8	Etonogestrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Oseltamivir	DC5WC0T	Oseltamivir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Ibutilide	DCG9ZH7	Ibutilide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Diazoxide	DCJY4N8	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Tamoxifen	DCM84H1	Tamoxifen	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Mefloquine + Tamoxifen	DCPMOSD	Tamoxifen	Primitive neuroectodermal tumor (Cell Line: TC-32)	[5]
Mefloquine + KN-62	DC4OXL1	KN-62	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Pargyline	DCPC4GY	Pargyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Idarubicin	DCI2AG9	Idarubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Epothilone B	DCLFS4N	Epothilone B	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + BRL-15572	DCK6VOQ	BRL-15572	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + GSK2126458	DCXDW60	GSK2126458	DD2 (Cell Line: DD2)	[5]
Mefloquine + Imatinib	DCU3WD2	Imatinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Probenecid	DCR7X1M	Probenecid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Darunavir	DCTMW9M	Darunavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Pramipexole	DCQDPEC	Pramipexole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Methylene blue	DC8251O	Methylene blue	DD2 (Cell Line: DD2)	[5]
Mefloquine + Methylene blue	DC3CKTO	Methylene blue	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Moricizine	DCBFEPM	Moricizine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Artemisinin	DC055CK	Artemisinin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Artemisinin	DC6XUXQ	Artemisinin	DD2 (Cell Line: DD2)	[5]
Mefloquine + Olanzapine	DC4BWDZ	Olanzapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Clascoterone	DC9RYA8	Clascoterone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Cefmenoxime	DC0B7CK	Cefmenoxime	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Trimethobenzamide	DCJ7RBK	Trimethobenzamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Omacetaxine mepesuccinate	DCJY0XJ	Omacetaxine mepesuccinate	DD2 (Cell Line: DD2)	[5]
Mefloquine + Omacetaxine mepesuccinate	DCDJJ89	Omacetaxine mepesuccinate	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Maprotiline	DCP1GBQ	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Teriflunomide	DCZY87T	Teriflunomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Acetohexamide	DC0MOJV	Acetohexamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Chlorambucil	DCTLSJ8	Chlorambucil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Brincidofovir	DCE1D59	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Sorafenib	DCF0PRY	Sorafenib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Desoxycorticosterone pivalate	DCGD429	Desoxycorticosterone pivalate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Prazosin	DCFTUOE	Prazosin	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Mefloquine + Chloroquine	DC9UL52	Chloroquine	DD2 (Cell Line: DD2)	[5]
Mefloquine + Asenapine	DC8XGER	Asenapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Piperaquine	DC6YLK3	Piperaquine	DD2 (Cell Line: DD2)	[5]
Mefloquine + Piperaquine	DCNO7DQ	Piperaquine	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + NVP-AUY922	DCOM1R3	NVP-AUY922	DD2 (Cell Line: DD2)	[5]
Mefloquine + NVP-AUY922	DC1W540	NVP-AUY922	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Mycophenolic acid	DCRE9FG	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Oxandrolone	DCH8BCZ	Oxandrolone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + JTC-801	DC44JIW	JTC-801	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Silver sulfadiazine	DCIJD2B	Silver sulfadiazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Olmesartan medoxomil	DCTTEBR	Olmesartan medoxomil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + PPADS	DCS0LYF	PPADS	DD2 (Cell Line: DD2)	[5]
Mefloquine + Metaxalone	DCUF7FS	Metaxalone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Busulfan	DC1IRCH	Busulfan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Atovaquone	DC7AZC0	Atovaquone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Atovaquone	DCM662B	Atovaquone	Hepatoblastoma (Cell Line: HB3)	[5]
Mefloquine + Aciclovir	DCO9JL1	Aciclovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Enoxacin	DCLJ4W0	Enoxacin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Raltegravir	DC4KDHN	Raltegravir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Albendazole	DCFU6M1	Albendazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mefloquine + Tetracycline	DCPULF5	Tetracycline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Mephenytoin + Mefloquine	DCHMWKN	Mephenytoin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Metformin + Mefloquine	DCCVZ4F	Metformin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Methocarbamol + Mefloquine	DCVTY29	Methocarbamol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Methoxsalen + Mefloquine	DC1JUMW	Methoxsalen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Metyrosine + Mefloquine	DCHA8XD	Metyrosine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Miconazole + Mefloquine	DCI5Q59	Miconazole	Hepatoblastoma (Cell Line: HB3)	[6]
Midostaurin + Mefloquine	DCVVVOY	Midostaurin	DD2 (Cell Line: DD2)	[5]
Midostaurin + Mefloquine	DC40MCL	Midostaurin	Hepatoblastoma (Cell Line: HB3)	[6]
Miglustat + Mefloquine	DC07YUW	Miglustat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
MK-3207 + Mefloquine	DCO9CWU	MK-3207	DD2 (Cell Line: DD2)	[5]
MK-3207 + Mefloquine	DCSYGJS	MK-3207	Hepatoblastoma (Cell Line: HB3)	[6]
ML323 + Mefloquine	DCAI9KV	ML323	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Nabilone + Mefloquine	DCRX2DW	Nabilone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Naftopidil + Mefloquine	DCTDB4W	Naftopidil	Hepatoblastoma (Cell Line: HB3)	[6]
Naltrexone + Mefloquine	DCX4YJK	Naltrexone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Naringenin + Mefloquine	DC6UP7U	Naringenin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Nitisinone + Mefloquine	DC3JM7R	Nitisinone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Nitisinone + Mefloquine	DCPXX4B	Nitisinone	DD2 (Cell Line: DD2)	[5]
Nitisinone + Mefloquine	DC7O0C4	Nitisinone	Hepatoblastoma (Cell Line: HB3)	[5]
Nitrosoglutathione + Mefloquine	DCJAU4N	Nitrosoglutathione	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Nizatidine + Mefloquine	DCLK2GV	Nizatidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Novobiocin + Mefloquine	DC32WOL	Novobiocin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Omacetaxine mepesuccinate + Mefloquine	DC7PHFF	Omacetaxine mepesuccinate	DD2 (Cell Line: DD2)	[5]
Omacetaxine mepesuccinate + Mefloquine	DCBQ31L	Omacetaxine mepesuccinate	Hepatoblastoma (Cell Line: HB3)	[6]
Otilonium bromide + Mefloquine	DC1JO3F	Otilonium bromide	DD2 (Cell Line: DD2)	[5]
Otilonium bromide + Mefloquine	DC1MFKQ	Otilonium bromide	Hepatoblastoma (Cell Line: HB3)	[5]
Panobinostat + Mefloquine	DC73SKF	Panobinostat	DD2 (Cell Line: DD2)	[5]
Panobinostat + Mefloquine	DC9J3LU	Panobinostat	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Paromomycin + Mefloquine	DC43V13	Paromomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Parthenolide + Mefloquine	DCBPDHS	Parthenolide	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Pentamidine + Mefloquine	DCVFQAL	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Pentostatin + Mefloquine	DCG20FA	Pentostatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
PHA-739358 + Mefloquine	DCNYP4X	PHA-739358	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Phenprocoumon + Mefloquine	DCX35IZ	Phenprocoumon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Picoplatin + Mefloquine	DCDXB0F	Picoplatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Pizotyline + Mefloquine	DCXSAH9	Pizotyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
PMID28460551-Compound-2 + Mefloquine	DCM5F1W	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Pomalidomide + Mefloquine	DCH4WUC	Pomalidomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Pramipexole + Mefloquine	DCO21AF	Pramipexole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Pyronaridine + Mefloquine	DCC23NU	Pyronaridine	DD2 (Cell Line: DD2)	[5]
Pyronaridine + Mefloquine	DCCW723	Pyronaridine	Hepatoblastoma (Cell Line: HB3)	[6]
Quinine + Mefloquine	DCLORWH	Quinine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Quinine + Mefloquine	DCFIEDB	Quinine	DD2 (Cell Line: DD2)	[5]
Quinine + Mefloquine	DCKQH8W	Quinine	Hepatoblastoma (Cell Line: HB3)	[5]
Ramelteon + Mefloquine	DCNBQXV	Ramelteon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Rifampin + Mefloquine	DCZ397W	Rifampin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Ritonavir + Mefloquine	DC9O4OW	Ritonavir	Hepatoblastoma (Cell Line: HB3)	[5]
Sarpogrelate + Mefloquine	DCM3YVP	Sarpogrelate	DD2 (Cell Line: DD2)	[5]
Sitagliptin + Mefloquine	DCONIPB	Sitagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Sitosterol + Mefloquine	DCI36WZ	Sitosterol	Hepatoblastoma (Cell Line: HB3)	[6]
SNDX-275 + Mefloquine	DCPC8F8	SNDX-275	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
SNS-032 + Mefloquine	DC2Q6CM	SNS-032	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
Sorafenib + Mefloquine	DCU9GQS	Sorafenib	DD2 (Cell Line: DD2)	[5]
Sorafenib + Mefloquine	DCXVF3T	Sorafenib	Hepatoblastoma (Cell Line: HB3)	[5]
Spironolactone + Mefloquine	DCCFANV	Spironolactone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Strontium ranelate + Mefloquine	DCLLO1O	Strontium ranelate	DD2 (Cell Line: DD2)	[5]
Sulfinpyrazone + Mefloquine	DCCM02Q	Sulfinpyrazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Sumatriptan + Mefloquine	DCAPLWU	Sumatriptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Tacrine + Mefloquine	DC7CKJI	Tacrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Tamoxifen + Mefloquine	DC3Y12V	Tamoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Testosterone + Mefloquine	DC8VEW6	Testosterone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Tetrandrine + Mefloquine	DCVLSWH	Tetrandrine	Hepatoblastoma (Cell Line: HB3)	[5]
THAPSIGARGIN + Mefloquine	DCMTDJ0	THAPSIGARGIN	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[5]
THAPSIGARGIN + Mefloquine	DCA718A	THAPSIGARGIN	Primitive neuroectodermal tumor (Cell Line: TC-32)	[5]
Theophylline + Mefloquine	DCXI7BY	Theophylline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Thiolactomycin + Mefloquine	DC4AC75	Thiolactomycin	DD2 (Cell Line: DD2)	[5]
Thiolactomycin + Mefloquine	DCKKKQ0	Thiolactomycin	Hepatoblastoma (Cell Line: HB3)	[6]
Tiagabine + Mefloquine	DCUG2ZJ	Tiagabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Tolazoline + Mefloquine	DCIUT34	Tolazoline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Tolvaptan + Mefloquine	DCQBLXF	Tolvaptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Topotecan + Mefloquine	DC2WBD4	Topotecan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[6]
Trametinib + Mefloquine	DC8K9SY	Trametinib	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[6]
Triamterene + Mefloquine	DCYQVY2	Triamterene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Trichostatin A + Mefloquine	DCYUDT5	Trichostatin A	DD2 (Cell Line: DD2)	[5]
Trifluoperazine + Mefloquine	DCBV1HA	Trifluoperazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Triflupromazine + Mefloquine	DC804QN	Triflupromazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Ursodeoxycholic acid + Mefloquine	DCL8YZQ	Ursodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Verapamil + Mefloquine	DCVIJ4O	Verapamil	DD2 (Cell Line: DD2)	[6]
Vorinostat + Mefloquine	DCXRP99	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
Vorinostat + Mefloquine	DCTPO49	Vorinostat	Hepatoblastoma (Cell Line: HB3)	[5]
Zileuton + Mefloquine	DCUN3GM	Zileuton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[5]
ZM-447439 + Mefloquine	DC4R0IA	ZM-447439	DD2 (Cell Line: DD2)	[5]
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⏷ Show the Full List of 285 DrugCom(s)

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Artesunate + Mefloquine	DCPG5FB	Artesunate	Plasmodium Falciparum Malaria	[7]
Azithromycin + Mefloquine	DCMXADR	Azithromycin	Coronavirus Disease 2019 (COVID-19)	[2]
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References

1	FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (NDA) 019578
2	ClinicalTrials.gov (NCT04347031) An Open Randomized Study of the Effectiveness of Mefloquine for the Treatment of Patients With COVID19. U.S. National Institutes of Health.
3	Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrob Agents Chemother. 2014 Aug;58(8):4885-93.
4	Mefloquine FDA Label
5	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
6	Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
7	ClinicalTrials.gov (NCT01659281) Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, Thailand