Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGHXQE)

Drug Name
AMX-256 Drug Info
Synonyms GLP-2 (XTEN formulation, Crohns disease), Amunix; GLP-2 (XTEN formulation, Crohns disease/short bowel syndrome), Amunix
Indication
Disease Entry ICD 11 Status REF
Short bowel syndrome KB89.1 Investigative [1]
Cross-matching ID
TTD Drug ID
DMGHXQE

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucagon-like peptide 2 receptor (GLP2R) TT1YWO5 GLP2R_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glucagon-like peptide 2 receptor (GLP2R) DTT GLP2R 1.807 2.138 2.202 2.632
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Short bowel syndrome
ICD Disease Classification KB89.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glucagon-like peptide 2 receptor (GLP2R) DTT GLP2R 6.12E-01 0.06 0.3
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 250).