Details of the Drug

General Information of Drug (ID: DMGHXQE)

Drug Name

AMX-256

Synonyms

GLP-2 (XTEN formulation, Crohns disease), Amunix; GLP-2 (XTEN formulation, Crohns disease/short bowel syndrome), Amunix

Indication

Disease Entry	ICD 11	Status	REF
Short bowel syndrome	KB89.1	Investigative	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucagon-like peptide 2 receptor (GLP2R)	TT1YWO5	GLP2R_HUMAN	Modulator	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Short bowel syndrome

ICD Disease Classification

KB89.1

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Glucagon-like peptide 2 receptor (GLP2R)	DTT	GLP2R	6.12E-01	0.06	0.3

Molecular Expression Atlas (MEA)

Jump to Detail Molecular Expression Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 250).