Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0CEY3)

• Drug Name: Lefaxin Drug Info
• Synonyms: PYRIDOSTIGMINE BROMIDE; 101-26-8; Mestinon; Kalimin; Regonal; Kalymin; Mestinon bromide; 3-((Dimethylcarbamoyl)oxy)-1-methylpyridin-1-ium bromide; 3-(Dimethylcarbamoyloxy)-1-methylpyridinium Bromide; Pyridostigmine (bromide); UNII-KVI301NA53; Piridostigmina bromuro [DCIT]; CCRIS 6798; HSDB 3924; 3-[(dimethylcarbamoyl)oxy]-1-methylpyridin-1-ium bromide; Pyridostigmini bromidum [INN-Latin]; EINECS 202-929-9; Ro 1-5130; Bromure de pyridostigmine [INN-French]; Pyridostigmini bromidum; Bromuro de piridostigmina [INN-Spanish

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 7550
  ChEBI ID: CHEMBL812
  CAS Number: CAS 101-26-8
  TTD Drug ID: DM0CEY3

Molecule-Related Drug Atlas

Drug(s) Targeting Coagulation factor Xa (F10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Apixaban	DM89JLN	Thrombosis	DB61-GB90	Approved	[4]
Rivaroxaban	DMQMBZ1	Deep vein thrombosis	BD71	Approved	[5]
DU-176b	DMCIJBH	Atrial fibrillation	BC81.3	Approved	[6]
Emicizumab	DM0AQ83	Factor VIII deficiency	3B10	Approved	[7]
BETRIXABAN	DM2C4RF	Venous thromboembolism	BD72	Approved	[8]
Lmw heparin	DMJPD06	Coagulation defect	3B10.0	Approved	[9]
Nadroparin calcium	DMBNKST	Coagulation defect	3B10.0	Approved	[10]
Fondaparinux sodium	DMWS3FH	Deep vein thrombosis	BD71	Approved	[11]
Danaparoid	DM6CLBN	Deep venous clot	BD71	Approved	[12]
Coagulation Factor IX	DM8HBJI	Haemophilia B	3B11.0	Approved	[13]

Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[14]
Selenium	DM25CGV	N. A.	N. A.	Approved	[15]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[16]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[17]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[18]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[19]
Rofecoxib	DM3P5DA	Osteoarthritis	FA00-FA05	Approved	[20]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[21]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[22]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[23]

Drug(s) Affected By Albumin (ALB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[24]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[25]
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[26]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[27]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[28]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[29]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[30]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[31]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[32]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[33]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Coagulation factor Xa (F10)	TTCIHJA	FA10_HUMAN	Inhibitor	[1]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Protein Interaction/Cellular Processes	[2]
Superoxide dismutase , mitochondrial (SOD2)	OTIWXGZ9	SODM_HUMAN	Gene/Protein Processing	[3]

References

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