Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0D7LA)

Drug Name
BROMODEOXYURIDINE Drug Info
Synonyms
5-BROMO-2'-DEOXYURIDINE; 59-14-3; Broxuridine; Bromodeoxyuridine; 5-Bromodeoxyuridine; BRDU; 5-BrdU; BUDR; 5-Bromouracil deoxyriboside; Bromouracil deoxyriboside; 5-Bromodesoxyuridine; 5-Bdu; Broxuridinum; Broxuridina; 5-Bromouracil-2-deoxyriboside; 5-Bromo-2-deoxyuridine; bromodeoxyuridine (brdu); Broxuridinum [INN-Latin]; Uridine, 5-bromo-2'-deoxy-; Broxuridina [INN-Spanish]; C9H11BrN2O5; NSC-38297; Bromoouridine; Radibud; CCRIS 818; Brudr; UNII-G34N38R2N1; HSDB 7477; CHEBI:472552; EINECS 200-415-9; 5-Budr; 5-bromo-2'-deoxy uridine
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
6035
ChEBI ID
CHEMBL222280
CAS Number
CAS 59-14-3
TTD Drug ID
DM0D7LA

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Investigative Drug(s)
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Mycobacterium Thymidine monophosphate kinase (MycB tmk)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetate Ion DMD08RH Discovery agent N.A. Investigative [3]
AMP-PNP DMTOK1D Discovery agent N.A. Investigative [4]
2'-deoxythymidine triphosphate DM9OEJT Discovery agent N.A. Investigative [3]
Deoxythymidine DMR90HY Discovery agent N.A. Investigative [3]
Diphosphate DMHY30B Discovery agent N.A. Investigative [3]
Thymidine-5'-Phosphate DMKM6NQ Discovery agent N.A. Investigative [3]
P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate DMM4VWD Discovery agent N.A. Investigative [5]
3'-Azido-3'-Deoxythymidine-5'-Monophosphate DMU08MN Discovery agent N.A. Investigative [3]
5-Hydroxymethyluridine-2'-Deoxy-5'-Monophosphate DMWVCJ1 Discovery agent N.A. Investigative [3]
CHLORODEOXYURIDINE DMQT3WJ Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor SOX-17 (SOX17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [2]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [2]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [2]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [2]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [7]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [2]
Ziprasidone DMM58JY Bipolar disorder 6A60 Approved [2]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mycobacterium Thymidine monophosphate kinase (MycB tmk) TT5B8AX KTHY_MYCTU Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Transcription factor SOX-17 (SOX17) OT9H4WWE SOX17_HUMAN Protein Interaction/Cellular Processes [2]

References

1 Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial ac... Bioorg Med Chem. 2008 Jun 1;16(11):6075-85.
2 A high-throughput screen for teratogens using human pluripotent stem cells. Toxicol Sci. 2014 Jan;137(1):76-90. doi: 10.1093/toxsci/kft239. Epub 2013 Oct 23.
3 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
5 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
6 Antiepileptic drugs are endocrine disruptors for the human fetal testis ex vivo. Toxicol Sci. 2023 Sep 28;195(2):169-183. doi: 10.1093/toxsci/kfad076.
7 Interleukin-19 as a translational indicator of renal injury. Arch Toxicol. 2015 Jan;89(1):101-6.