Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0J5KF)

• Drug Name: Glycerol-2-Phosphate Drug Info
• Synonyms: 1,3-dihydroxypropan-2-yl phosphate; Glycerol 2-phosphate; 2-glycerophosphate; NCGC00166037-02; b-glycerol-phosphate; beta-glycerol-phosphate; AC1MU1UF; glycerol 2-phosphate(2-); glycerol 2-phosphate dianion; CHEBI:58083; STL280277; 2-(phosphonatooxy)propane-1,3-diol; AKOS022142160

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 2526
  ChEBI ID: CHEBI:17270
  CAS Number: CAS 17181-54-3
  TTD Drug ID: DM0J5KF

Molecule-Related Drug Atlas

Drug(s) Targeting Bacterial Triosephosphate isomerase (Bact TPI)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-Phosphoglyceric Acid	DMX6GH5	Discovery agent	N.A.	Investigative	[1]
3-Phosphoglycerol	DM9BDV2	Discovery agent	N.A.	Investigative	[1]
3-Phosphoglyceric Acid	DMIK9VO	Discovery agent	N.A.	Investigative	[1]
2-Phosphoglycolic Acid	DMO14NH	Discovery agent	N.A.	Investigative	[1]
3-Hydroxypyruvic Acid	DM67QDT	Discovery agent	N.A.	Investigative	[1]

Drug(s) Affected By Alkaline phosphatase, tissue-nonspecific isozyme (ALPL)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[4]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[5]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[6]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[7]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[8]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[9]
Procaine	DM4LSNE	Anaesthesia	9A78.6	Approved	[10]
Glucosamine	DM4ZLFD	Osteoarthritis	FA00-FA05	Approved	[11]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[12]
Aldosterone	DM9S2JW	Hypertension	BA00-BA04	Approved	[13]

Drug(s) Affected By Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[14]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[15]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[16]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[17]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[18]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[19]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[20]
Dasatinib	DMJV2EK	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[21]
Diclofenac	DMPIHLS	Chronic renal failure	GB61.Z	Approved	[22]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[23]

Drug(s) Affected By Phosphate-regulating neutral endopeptidase PHEX (PHEX)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Phosphate	DMUXQG7	Constipation	DD91.1	Approved	[3]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[24]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[25]

Drug(s) Affected By Fibroblast growth factor 23 (FGF23)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[26]
Pamidronate	DMB4AVP	Bone Paget disease		Approved	[27]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[28]
Phosphate	DMUXQG7	Constipation	DD91.1	Approved	[3]
Cholecalciferol	DMGU74E	Adult acute monocytic leukemia		Approved	[26]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[29]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[30]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Triosephosphate isomerase (Bact TPI)	TTNS6X4	TPIS_PLAFA	Inhibitor	[1]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Alkaline phosphatase, tissue-nonspecific isozyme (ALPL)	OTG7J4BP	PPBT_HUMAN	Gene/Protein Processing	[2]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1)	OT3MPPYX	ENPP1_HUMAN	Gene/Protein Processing	[2]
Fibroblast growth factor 23 (FGF23)	OTZT523D	FGF23_HUMAN	Gene/Protein Processing	[3]
Phosphate-regulating neutral endopeptidase PHEX (PHEX)	OTG7N3J7	PHEX_HUMAN	Gene/Protein Processing	[2]

References

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