Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0J5KF)

Drug Name

Glycerol-2-Phosphate Drug Info

Synonyms

1,3-dihydroxypropan-2-yl phosphate; Glycerol 2-phosphate; 2-glycerophosphate; NCGC00166037-02; b-glycerol-phosphate; beta-glycerol-phosphate; AC1MU1UF; glycerol 2-phosphate(2-); glycerol 2-phosphate dianion; CHEBI:58083; STL280277; 2-(phosphonatooxy)propane-1,3-diol; AKOS022142160

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2526
ChEBI ID: CHEMBL1232903
CAS Number: CAS 17181-54-3
TTD Drug ID: DM0J5KF

Molecule-Related Drug Atlas

Molecule Type:

DTT

DOT

Drug Status:

Investigative Drug(s)

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Bacterial Triosephosphate isomerase (Bact TPI)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-Phosphoglyceric Acid	DMX6GH5	Discovery agent	N.A.	Investigative	[1]
3-Phosphoglycerol	DM9BDV2	Discovery agent	N.A.	Investigative	[1]
3-Phosphoglyceric Acid	DMIK9VO	Discovery agent	N.A.	Investigative	[1]
2-Phosphoglycolic Acid	DMO14NH	Discovery agent	N.A.	Investigative	[1]
3-Hydroxypyruvic Acid	DM67QDT	Discovery agent	N.A.	Investigative	[1]
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Drug(s) Affected By Phosphate-regulating neutral endopeptidase PHEX (PHEX)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Phosphate	DMUXQG7	Constipation	DD91.1	Approved	[3]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[4]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Triosephosphate isomerase (Bact TPI)	TTNS6X4	TPIS_PLAFA	Inhibitor	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Phosphate-regulating neutral endopeptidase PHEX (PHEX)	OTG7N3J7	PHEX_HUMAN	Gene/Protein Processing	[2]

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References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	The role of tissue-nonspecific alkaline phosphatase in the phosphate-induced activation of alkaline phosphatase and mineralization in SaOS-2 human osteoblast-like cells. Mol Cell Biochem. 2008 Aug;315(1-2):51-60.
3	Bone as a source of FGF23: regulation by phosphate?. Bone. 2004 Nov;35(5):1192-9. doi: 10.1016/j.bone.2004.06.014.
4	BET bromodomain protein inhibition is a therapeutic option for medulloblastoma. Oncotarget. 2013 Nov;4(11):2080-95.
5	Identification of a transcriptomic signature of food-relevant genotoxins in human HepaRG hepatocarcinoma cells. Food Chem Toxicol. 2020 Jun;140:111297. doi: 10.1016/j.fct.2020.111297. Epub 2020 Mar 28.