Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3NCM1)

Drug Name

Alpha-D-Mannose-6-Phosphate Drug Info

Synonyms

alpha-D-mannose-6-phosphate; 6-H2PO3Manalpha; alpha-D-mannose 6-phosphate; (6P)Manalpha; Man6P; (6P)Mana; 6-O-phosphono-alpha-D-mannopyranose; UNII-C77UQ006XD; C77UQ006XD; CHEBI:43896; Mannose 6-phosphate; M6P; 1syo; 1m6p; 1sz0; AC1L9KGE; SCHEMBL742653; CHEMBL402001; NBSCHQHZLSJFNQ-PQMKYFCFSA-N; ZINC4096188; DB02900; alpha-D-Mannopyranose, 6-(dihydrogen phosphate); WURCS=2.0/1,1,0/[a1122h-1a_1-5_6*OPO/3O/3=O]/1/; [(2R,3S,4S,5S,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 447096
ChEBI ID: CHEBI:43896
CAS Number: CAS 40436-60-0
TTD Drug ID: DM3NCM1

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Approved Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Pseudomonas Phosphomannomutase/phosphoglucomutase (Pseudo algC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-serine-O-phosphate	DMTJ1NH	Discovery agent	N.A.	Investigative	[1]
Alpha-D-Glucose-6-Phosphate	DMR0EVN	Discovery agent	N.A.	Investigative	[1]
D-Mannose 1-Phosphate	DM7O1IW	Discovery agent	N.A.	Investigative	[1]
Alpha-D-Glucose-1-Phosphate	DMU36HT	Discovery agent	N.A.	Investigative	[1]
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Drug(s) Targeting Mannose-6-phosphate receptor (M6PR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alglucosidase alfa	DM4LOD0	Pompe disease	5C51.3	Approved	[2]
1-3 Sugar Ring of Pentamannosyl 6-Phosphate	DMRO1IU	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mannose-6-phosphate receptor (M6PR)	TT95ICL	MPRD_HUMAN	Inhibitor	[1]
Pseudomonas Phosphomannomutase/phosphoglucomutase (Pseudo algC)	TTLP3GX	ALGC_PSEAE	Inhibitor	[1]

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References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	Early treatment with alglucosidase alpha prolongs long-term survival of infants with Pompe disease. Pediatr Res. 2009 Sep;66(3):329-35.