Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM40SEU)

Drug Name

oxalate Drug Info

Synonyms

oxalate2-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTP

Drug Status:

Investigative Drug(s)

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Drug(s) Transported By Sulfate anion transporter 1 (SLC26A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SULFATE	DMW0ZBF	Discovery agent	N.A.	Investigative	[2]
BICARBONATE	DMT5E36	Discovery agent	N.A.	Investigative	[5]
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Drug(s) Transported By Anion exchange transporter (SLC26A6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SULFATE	DMW0ZBF	Discovery agent	N.A.	Investigative	[6]
BICARBONATE	DMT5E36	Discovery agent	N.A.	Investigative	[7]
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Drug(s) Transported By Anion exchange transporter (SLC26A7)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SULFATE	DMW0ZBF	Discovery agent	N.A.	Investigative	[3]
BICARBONATE	DMT5E36	Discovery agent	N.A.	Investigative	[8]
NITRATE	DMVFB93	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Sulfate anion transporter 1 (SLC26A1)	DTJ785O	S26A1_HUMAN	Substrate	[2]
Anion exchange transporter (SLC26A7)	DTOTME4	S26A7_HUMAN	Substrate	[3]
Anion exchange transporter (SLC26A6)	DTVGOLN	S26A6_HUMAN	Substrate	[4]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4538).
2	Mutations in SLC26A1 Cause Nephrolithiasis. Am J Hum Genet. 2016 Jun 2;98(6):1228-1234.
3	The Transporter Classification Database (TCDB): recent advances. Nucleic Acids Res. 2016 Jan 4;44(D1):D372-9. (ID: 2.A.53.2.6)
4	Oxalate (urine, plasma)
5	SLC26A Gene Family Participate in pH Regulation during Enamel Maturation. PLoS One. 2015 Dec 15;10(12):e0144703.
6	The Transporter Classification Database (TCDB): recent advances. Nucleic Acids Res. 2016 Jan 4;44(D1):D372-9. (ID: 2.A.53.2.7)
7	Metabolon disruption: a mechanism that regulates bicarbonate transport. EMBO J. 2005 Jul 20;24(14):2499-511.
8	Vasopressin induces expression of the Cl-/HCO3- exchanger SLC26A7 in kidney medullary collecting ducts of Brattleboro rats. Am J Physiol Renal Physiol. 2006 May;290(5):F1194-201.