Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9LUTV)

Drug Name

RXC006 Drug Info

Synonyms

AZD5055

Indication

Disease Entry	ICD 11	Status	REF
Idiopathic pulmonary fibrosis	CB03.4	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Protein-serine O-palmitoleoyltransferase porcupine (PORCN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ETC-1922159	DMY0HU6	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
LGK974	DMAG6BV	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein-serine O-palmitoleoyltransferase porcupine (PORCN)	TTNFBTO	PORCN_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT05134727) A Double-blind, Randomized, Placebo-controlled Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of Oral AZD5055 Following Single and Multiple Ascending Doses. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Redx
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)