Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBGHPE)

Drug Name
octanol Drug Info
Synonyms
1-octanol; Octan-1-ol; octanol; 111-87-5; N-octanol; Capryl alcohol; Octyl alcohol; caprylic alcohol; n-Octyl alcohol; Heptyl carbinol; 1-Hydroxyoctane; Primary octyl alcohol; Alcohol C-8; n-Octan-1-ol; Octilin; Sipol L8; Alfol 8; Lorol 20; Dytol M-83; n-Caprylic alcohol; 1-Octyl alcohol; n-Heptyl carbinol; EPAL 8; octyl-alcohol; Alcohols, C6-12; N-octyl-alcohol; Octyl alcohol, normal-primary; C8 alcohol; Fatty alcohol(C8); Octyl alcohol, primary; Caswell No. 611A; Octyl alcohol (natural); FEMA Number 2800; Lorol C 8-98; n-Capryl alcohol
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
957
ChEBI ID
CHEMBL16188
CAS Number
CAS 111-87-5
TTD Drug ID
DMBGHPE
INTEDE Drug ID
DR2004

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
Drug Status:
Investigative Drug(s)
Clinical Trial Drug(s)
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Gap junction alpha-8 protein (Cx50)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PQ-1 DMXLPO6 Solid tumour/cancer 2A00-2F9Z Investigative [13]
Drug(s) Targeting Gap junction alpha-1 protein (GJA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Granexin gel DMZS2R7 Diabetic foot ulcer BD54 Phase 3 [24]
Act1 DMXYRPO Wound healing EL8Y Phase 3 [25]
HCB1019 DMX8C6J Diabetic macular edema 9B71.02 Phase 2 [26]
ALMB-0168 DMB0LSF Osteosarcoma 2B51 Phase 1/2 [27]
ALMB-0166 DM3MH2H Spinal cord injury ND51.2 Phase 1 [28]
Drug(s) Metabolized By Alcohol dehydrogenase class-I gamma (ADH1C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [29]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [23]
Pyrene-1-aldehyde DMEF6IP N. A. N. A. Investigative [23]
Hydroxymethylpyrene DMPGAR2 N. A. N. A. Investigative [23]
BRN-2330710 DM87VP6 N. A. N. A. Investigative [23]
Pyrenemethanol DMGJ0RM N. A. N. A. Investigative [23]
Octanal DMTN0OK N. A. N. A. Investigative [23]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Metabolized By Alcohol dehydrogenase class-II (ADH4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [23]
ANDROSTERONE DMITJAK N. A. N. A. Phase 3 [30]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [23]
Pyrene-1-aldehyde DMEF6IP N. A. N. A. Investigative [23]
Hydroxymethylpyrene DMPGAR2 N. A. N. A. Investigative [23]
BRN-2330710 DM87VP6 N. A. N. A. Investigative [23]
Pyrenemethanol DMGJ0RM N. A. N. A. Investigative [23]
Octanal DMTN0OK N. A. N. A. Investigative [23]
⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Connexin-23 (Cx23) TTDQPXA CXE1_HUMAN Inhibitor [2]
Connexin-25 (Cx25) TTZ7POK CXB7_HUMAN Inhibitor [3]
Connexin-30 (Cx30) TTAU8SJ CXB6_HUMAN Inhibitor [4]
Connexin-32 (Cx32) TTHWA40 CXB1_HUMAN Inhibitor [5]
Connexin-45 (Cx45) TTEP7OC CXG1_HUMAN Inhibitor [6]
Connexin-59 (Cx59) TTYP9NL CXA9_HUMAN Inhibitor [7]
Connexin-62 (Cx62) TTQMI2N CXA10_HUMAN Inhibitor [8]
Gap junction alpha-1 protein (GJA1) TT4F7SL CXA1_HUMAN Inhibitor [9]
Gap junction alpha-3 protein (Cx46) TTFZRG0 CXA3_HUMAN Inhibitor [10]
Gap junction alpha-4 protein (Cx37) TTQO1VY CXA4_HUMAN Inhibitor [11]
Gap junction alpha-5 protein (Cx40) TTFQKZ7 CXA5_HUMAN Inhibitor [12]
Gap junction alpha-8 protein (Cx50) TTJ7ATH CXA8_HUMAN Inhibitor [13]
Gap junction beta-2 protein (Cx26) TTRGZX3 CXB2_HUMAN Inhibitor [14]
Gap junction beta-3 protein (Cx31) TTVRQ8L CXB3_HUMAN Inhibitor [15]
Gap junction beta-4 protein (Cx30.3) TTBRDFI CXB4_HUMAN Inhibitor [16]
Gap junction beta-5 protein (Cx31.1) TTL9MHP CXB5_HUMAN Inhibitor [17]
Gap junction delta-2 protein (Cx36) TTOZAFI CXD2_HUMAN Inhibitor [18]
Gap junction delta-3 protein (Cx31.9) TT7C18W CXD3_HUMAN Inhibitor [19]
Gap junction delta-4 protein (Cx40.1) TTL07NQ CXD4_HUMAN Inhibitor [20]
Gap junction gamma-2 protein (Cx47) TTPOCAL CXG2_HUMAN Inhibitor [21]
Gap junction gamma-3 protein (Cx30.2) TTUW608 CXG3_HUMAN Inhibitor [22]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Alcohol dehydrogenase class-II (ADH4) DEOCWU3 ADH4_HUMAN Substrate [23]
Alcohol dehydrogenase class-I gamma (ADH1C) DEM1HNL ADH1G_HUMAN Substrate [23]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4278).
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 714).
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 715).
4 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 717).
5 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 723).
6 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 729).
7 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 733).
8 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 734).
9 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 728).
10 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 730).
11 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 725).
12 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 726).
13 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 732).
14 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 716).
15 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 720).
16 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 719).
17 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 721).
18 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 724).
19 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 722).
20 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 727).
21 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 731).
22 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 718).
23 Oxidation of alcohols and reduction of aldehydes derived from methyl- and dimethylpyrenes by cDNA-expressed human alcohol dehydrogenases. Toxicology. 2008 Mar 12;245(1-2):65-75.
24 Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.
25 Company report (FirstString Research)
26 Clinical pipeline report, company report or official report of OcuNexus Therapeutics.
27 Clinical pipeline report, company report or official report of AlaMab Therapeutics
28 Clinical pipeline report, company report or official report of AlaMab Therapeutics
29 Natural alcohol exposure: is ethanol the main substrate for alcohol dehydrogenases in animals? Chem Biol Interact. 2011 May 30;191(1-3):14-25.
30 13-cis-retinoic acid competitively inhibits 3 alpha-hydroxysteroid oxidation by retinol dehydrogenase RoDH-4: a mechanism for its anti-androgenic effects in sebaceous glands? Biochem Biophys Res Commun. 2003 Mar 28;303(1):273-8.