Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBJ8KG)

Drug Name

Urtoxazumab Drug Info

Synonyms

TMA-15; Anti shiga-like toxin 2 humanized MAb, Teijin; HuVTm1.1.1; Anti-SLT-2 humanized MAb (E coli infection), Teijin

Indication

Disease Entry	ICD 11	Status	REF
Escherichia coli infection	1A03	Discontinued in Phase 2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Enterobacteria Shiga-like toxin 2B (EntBac stxB2)	TTRV7FQ	STXB_BP933	Not Available	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021716)
2	Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli. Antimicrob Agents Chemother. 2010 Jan;54(1):239-43.