Details of the Drug

General Information of Drug (ID: DMBJ8KG)

Drug Name

Urtoxazumab

Synonyms

TMA-15; Anti shiga-like toxin 2 humanized MAb, Teijin; HuVTm1.1.1; Anti-SLT-2 humanized MAb (E coli infection), Teijin

Indication

Disease Entry	ICD 11	Status	REF
Escherichia coli infection	1A03	Discontinued in Phase 2	[1]
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Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Enterobacteria Shiga-like toxin 2B (EntBac stxB2)	TTRV7FQ	STXB_BP933	Not Available	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021716)
2	Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli. Antimicrob Agents Chemother. 2010 Jan;54(1):239-43.